BDBM85330 CAS_68647::NSC_68647::ONDANSETRON::Ondansetron hydrochloride
SMILES Cc1nccn1CC1CCc2c(C1=O)c1ccccc1n2C
InChI Key InChIKey=FELGMEQIXOGIFQ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 116 hits for monomerid = 85330
Affinity DataKi: 0.770nMAssay Description:Compound was evalated for its in vitro affinity at serotonergic 5-hydroxytryptamine 3 receptor by radioligand binding assay , using [3H]-LY 278584 in...More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:In vitro affinity for 5-hydroxytryptamine 3 (5-HT3) receptor by displacement of [3H]BRL-43694 from rat entorhinal cortexMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Binding affinity for 5-hydroxytryptamine 3 receptor from rat cortex using [3H]BRL-43694 as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:The binding affinity was measured on muscarine M2 receptor using [3H]- N-Me-SCOPOL as radioligand.More data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Displacement of [3H]- GR-65,630 binding to 5-hydroxytryptamine 3 receptor in rat brain cortical membranesMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:The binding affinity of the compound was measured on imidazoline I2 receptor using [3H]- indazoxan as radioligand.More data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 1D receptor in rat cortical membranes using [3H]5-HT as a radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:pKi value for inhibition of [3H]LY-278584 binding to 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.80nMAssay Description:Displacement of [3H]granisetron from human 5HT3A receptor expressed in HEK293 cells by filter binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.20nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 (5-HT3) receptor in rat brain cortical membranes using radioligand [3H]quipazineChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 3.20nMAssay Description:Binding affinity to 5-hydroxytryptamine 3 receptor was determined in rat cerebro cortical membranes using [3H]quipazine.More data for this Ligand-Target Pair
Affinity DataKi: 3.30nMAssay Description:Compound was evaluated for its binding affinity for 5-hydroxytryptamine 3 receptor by measuring displacement [3H]GR-65630 in rat cerebral cortexMore data for this Ligand-Target Pair
Affinity DataKi: 3.30nMAssay Description:Binding affinity to 5-hydroxytryptamine 3 receptor of neuronal in the afferent rabbit vagusMore data for this Ligand-Target Pair
Affinity DataKi: 3.31nMAssay Description:Potency at neuronal 5-hydroxytryptamine 3 receptors in the rabbit heartMore data for this Ligand-Target Pair
Affinity DataKi: 3.40nMAssay Description:Binding affinity to human HT3A receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A(Mouse)
Institut De Recherches Servier
Curated by PDSP Ki Database
Institut De Recherches Servier
Curated by PDSP Ki Database
Affinity DataKi: 6.20nMAssay Description:Displacement of the 5-hydroxytryptamine 3 receptor ligand [3H]GR-65630 from rat brain cortical membranes.More data for this Ligand-Target Pair
Affinity DataKi: 6.5nMAssay Description:Displacement of binding of [3H]-BRL 43694 to 5-hydroxytryptamine 3 receptor in rat cerebral cortexMore data for this Ligand-Target Pair
Affinity DataKi: 7.60nMAssay Description:Compound was evaluated for its ability to displace [3H]quipazine binding to 5-hydroxytryptamine 3 receptor sites in NG 108-15. More data for this Ligand-Target Pair
Affinity DataKi: 7.60nMAssay Description:Binding affinity against radioligand [3H]quipazine labeled 5-hydroxytryptamine 3 receptor sites in neuroblastoma-glioma (NG108-15) cells.More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A(Guinea pig)
Syntex Discovery Research
Curated by PDSP Ki Database
Syntex Discovery Research
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 3A(Mouse)
Institut De Recherches Servier
Curated by PDSP Ki Database
Institut De Recherches Servier
Curated by PDSP Ki Database
Affinity DataKi: 12nMAssay Description:The binding affinity was measured for 5-hydroxytryptamine 3 receptor on NG 108-15 cell line of mouse neuroblastoma-glioma cells in presence of [3H]5 ...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A(Mouse)
Institut De Recherches Servier
Curated by PDSP Ki Database
Institut De Recherches Servier
Curated by PDSP Ki Database
Affinity DataKi: 16nMAssay Description:In vitro inhibition of rat liver dihydrofolate reductase.More data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Binding affinity towards 5-hydroxytryptamine 3 receptor by displacement of [3H]2 in Neuroblastoma-Glioma NG-108-15 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:In vitro binding affinity for the 5-hydroxytryptamine 3 receptor was determined with NG-108-15 mouse neuroblastoma-glioma cellsMore data for this Ligand-Target Pair
Affinity DataKi: 680nMAssay Description:The binding affinity of the compound was measured on cholecystokinin type B receptor using [3H]- CCK-8 as radioligand.More data for this Ligand-Target Pair
Affinity DataKi: 680nMAssay Description:The binding affinity of the compound was measured on sigma receptor using [3H]- (+)-3-PPP as radioligand.More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]-5-CT from human 5-HT7b receptor expressed in HEK293 cells measured after 1 hr by Microbeta plate reader methodMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:In vitro affinity at serotonergic 5-hydroxytryptamine 4 receptor by radioligand binding assay using [3H]GR-113808 in rat striatum membranes.More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Rat)
National Institute of Neurological Disorders and Stroke
Curated by PDSP Ki Database
National Institute of Neurological Disorders and Stroke
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 7(Rat)
National Institute of Neurological Disorders and Stroke
Curated by PDSP Ki Database
National Institute of Neurological Disorders and Stroke
Curated by PDSP Ki Database
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of binding of [3H]5-HT to 5-hydroxytryptamine 1 receptor in rat cerebral cortexMore data for this Ligand-Target Pair
Affinity DataKi: 1.20E+3nMAssay Description:The binding affinity of the compound was measured on 5-hydroxytryptamine 4 receptor using [3H]- GR-113,808 as radioligand.More data for this Ligand-Target Pair
Affinity DataKi: 2.90E+3nMAssay Description:The binding affinity of the compound was measured on mu-opiate receptor using [3H]- naloxone as radioligand.More data for this Ligand-Target Pair
Affinity DataKi: >3.00E+3nMAssay Description:In vitro Binding affinity towards alpha-7 nAChR was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 3.70E+3nMAssay Description:The binding affinity of the compound was measured on 5-hydroxytryptamine 1B receptor using [3H]- serotonin as radioligand.More data for this Ligand-Target Pair
Affinity DataKi: 5.00E+3nMAssay Description:The binding affinity of the compound was measured on 5-hydroxytryptamine 1C receptor using [3H]- serotonin as radioligand.More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A(Guinea pig)
Syntex Discovery Research
Curated by PDSP Ki Database
Syntex Discovery Research
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 1A/1B/1D/1F/2A/2B/2C/3A/3B/4/5A/5B/6/7(Rat)
Solvay Duphar
Curated by ChEMBL
Solvay Duphar
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]- GR-65,630 binding to 5-hydroxytryptamine 3 receptor in rat brain cortical membranesMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]- GR-65,630 binding to 5-hydroxytryptamine 3 receptor in rat brain cortical membranesMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:The binding affinity of the compound was measured on muscarine M2 receptor using [3H]- N-Me-SCOPOL as radioligand.More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1S(Rat)
Solvay Duphar
Curated by ChEMBL
Solvay Duphar
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:The binding affinity of the compound was measured on cholecystokinin type A receptor using [3H]- CCK-8 as radioligand.More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1S(Rat)
Solvay Duphar
Curated by ChEMBL
Solvay Duphar
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type calcium channel dihydropyridine site of rat brainMore data for this Ligand-Target Pair
Affinity DataKi: 1.00E+4nMAssay Description:The binding affinity was measured on 5-hydroxytryptamine 2 receptor using [3H]- spiperone as radioligand.More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-raclopride from human D2L receptor expressed in HEK293 cells measured after 1 hr by Microbeta plate reader methodMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-ketanserin from human 5-HT2A receptor expressed in CHO-K1 cells measured after 1.5 hrs by Microbeta plate reader methodMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in HEK293 cells measured after 1 hr by Microbeta plate reader methodMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A(Guinea pig)
Syntex Discovery Research
Curated by PDSP Ki Database
Syntex Discovery Research
Curated by PDSP Ki Database