Affinity DataKi: <0.100nMAssay Description:Binding affinity against human leukocyte ElastaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Binding affinity of the compound for purified Human neutrophil elastase was determined in vitro.More data for this Ligand-Target Pair
TargetChymotrypsin-like elastase family member 1(Homo sapiens (Human))
Merrell Dow Research Institute
Curated by ChEMBL
Merrell Dow Research Institute
Curated by ChEMBL
Affinity DataKi: 0.580nMAssay Description:Binding affinity against human ElastaseMore data for this Ligand-Target Pair
TargetChymotrypsin-like elastase family member 1(Homo sapiens (Human))
Merrell Dow Research Institute
Curated by ChEMBL
Merrell Dow Research Institute
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Binding affinity against human ElastaseMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Compound was evaluated In vitro for inhibition of human neutrophil elastaseMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Tested for rate of substrate hydrolysis in the presence of human neutrophil elastaseMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:In vitro inhibition of human neutrophil elastaseMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:In vitro inhibition of human neutrophil elastaseMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Binding affinity of the compound for purified Human neutrophil elastase was determined in the presence of pig liver esterase, in vitro.More data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:The compound was tested for its potency to inhibit human neutrophil elastase activityMore data for this Ligand-Target Pair
Affinity DataKi: 6.30nMAssay Description:Binding affinity against human Elastase for more active diasteriomerMore data for this Ligand-Target Pair
Affinity DataKi: 7nMAssay Description:In vitro inhibitory activity against human neutrophil elastase was determined at a dose of 100 mg/kgMore data for this Ligand-Target Pair
Affinity DataKi: 7nMAssay Description:Binding affinity against human Elastase for more active diasteriomerMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Compound was evaluated In vitro for inhibition of human neutrophil elastaseMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Tested for inhibitory activity against calpain.More data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Inhibitory activity against chicken gizzard smooth muscle calpainMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:In vitro inhibition of human neutrophil elastaseMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Binding affinity of the compound for purified Human neutrophil elastase was determined in vitro.More data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:pA2 value towards endothelin receptor A was determined as functional ETA antagonismMore data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Tested for inhibition of substrate hydrolysis in the presence of porcine kidney esterase at a concentration of 10 nMMore data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Compound was evaluated In vitro for inhibition of human neutrophil elastaseMore data for this Ligand-Target Pair
TargetChymotrypsin-like elastase family member 1/2A(Sus scrofa (Pig))
Merrell Dow Research Institute
Curated by ChEMBL
Merrell Dow Research Institute
Curated by ChEMBL
Affinity DataKi: 15nMAssay Description:Binding affinity for porcine ElastaseMore data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:The compound was tested for its potency to inhibit human neutrophil elastase activityMore data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Binding affinity of the compound for purified Human neutrophil elastase was determined in the presence of pig liver esterase, in vitro.More data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Binding affinity against alpha-chymotrypsinMore data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:In vitro inhibition of human neutrophil elastaseMore data for this Ligand-Target Pair
Affinity DataKi: 21nMAssay Description:In vitro inhibition of human neutrophil elastaseMore data for this Ligand-Target Pair
Affinity DataKi: 24nMAssay Description:In vitro inhibition of human neutrophil elastaseMore data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:In vitro inhibitory activity against human neutrophil elastase was determined at a dose of 50 mg/kgMore data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Binding affinity of the compound for purified Human neutrophil elastase was determined in the presence of pig liver esterase, in vitro.More data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Binding affinity of the compound for purified Human neutrophil elastase was determined in vitro.More data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Binding affinity of the compound for purified Human neutrophil elastase was determined in the presence of pig liver esterase, in vitro.More data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Binding affinity of the compound for purified Human neutrophil elastase was determined in the presence of pig liver esterase, in vitro.More data for this Ligand-Target Pair
Affinity DataKi: 28nMAssay Description:In vitro inhibition of human neutrophil elastaseMore data for this Ligand-Target Pair
TargetChymotrypsin-like elastase family member 1/2A(Sus scrofa (Pig))
Merrell Dow Research Institute
Curated by ChEMBL
Merrell Dow Research Institute
Curated by ChEMBL
Affinity DataKi: 29nMAssay Description:Binding affinity against rat Cathepsin GMore data for this Ligand-Target Pair
Affinity DataKi: 29nMAssay Description:In vitro inhibition of human neutrophil elastaseMore data for this Ligand-Target Pair
TargetChymotrypsin-like elastase family member 1/2A(Sus scrofa (Pig))
Merrell Dow Research Institute
Curated by ChEMBL
Merrell Dow Research Institute
Curated by ChEMBL
Affinity DataKi: 32nMAssay Description:Binding affinity for porcine ElastaseMore data for this Ligand-Target Pair
Affinity DataKi: 33nMAssay Description:Tested for inhibitory activity against calpain.More data for this Ligand-Target Pair
TargetChymotrypsin-like elastase family member 1/2A(Sus scrofa (Pig))
Merrell Dow Research Institute
Curated by ChEMBL
Merrell Dow Research Institute
Curated by ChEMBL
Affinity DataKi: 33nMAssay Description:Binding affinity for porcine ElastaseMore data for this Ligand-Target Pair
Affinity DataKi: 39nMAssay Description:In vitro inhibition of human neutrophil elastaseMore data for this Ligand-Target Pair
Affinity DataKi: 43nMAssay Description:In vitro inhibitory activity against human neutrophil elastase was determined at a dose of 50 mg/kgMore data for this Ligand-Target Pair
Affinity DataKi: 44nMAssay Description:Compound was evaluated In vitro for inhibition of human neutrophil elastaseMore data for this Ligand-Target Pair
Affinity DataKi: 44nMAssay Description:In vitro inhibition of human neutrophil elastaseMore data for this Ligand-Target Pair
TargetChymotrypsin-like elastase family member 1(Homo sapiens (Human))
Merrell Dow Research Institute
Curated by ChEMBL
Merrell Dow Research Institute
Curated by ChEMBL
Affinity DataKi: 44nMAssay Description:Binding affinity against human ElastaseMore data for this Ligand-Target Pair
Affinity DataKi: 55nMAssay Description:The compound was tested for its potency to inhibit human neutrophil elastase activityMore data for this Ligand-Target Pair
Affinity DataKi: 59nMAssay Description:In vitro inhibitory activity against human neutrophil elastase was determined at a dose of 50 mg/kgMore data for this Ligand-Target Pair
Affinity DataKi: 60nMAssay Description:Inhibition of alpha-chymotrypsinMore data for this Ligand-Target Pair
Affinity DataKi: 60nMAssay Description:Inhibition of alpha-chymotrypsinMore data for this Ligand-Target Pair
Affinity DataKi: 60nMAssay Description:In vitro inhibitory activity against human neutrophil elastase was determined at a dose of 50 mg/kgMore data for this Ligand-Target Pair
Affinity DataKi: 70nMAssay Description:In vitro inhibition of human neutrophil elastaseMore data for this Ligand-Target Pair