Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant full-length human aPKCzeta expressed in Sf21 insect cells using 5FAM-ERMRPRKRQGSVRRRV-NH2 as substrate in presence of ATP a...More data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of recombinant full-length human aPKCiota using CREBtide as substrate incubated for 3 hrs in presence of ATP by kinase Glo luminescent ass...More data for this Ligand-Target Pair
Affinity DataIC50: 270nMAssay Description:Inhibition of recombinant full-length human aPKCzeta using ERMRPRKRQGSVRRRV as substrate in presence of ATP by ADP Quest kit assayMore data for this Ligand-Target Pair
Affinity DataIC50: 360nMAssay Description:Inhibition of recombinant full-length human aPKCzeta using CREBtide as substrate incubated for 3 hrs in presence of ATP by Kinase Glo luminescent ass...More data for this Ligand-Target Pair
Affinity DataIC50: 380nMAssay Description:Inhibition of recombinant full-length human aPKCzeta using CREBtide as substrate incubated for 3 hrs in presence of ATP by Kinase Glo luminescent ass...More data for this Ligand-Target Pair
Affinity DataIC50: 420nMAssay Description:Inhibition of recombinant full-length human aPKCzeta using CREBtide as substrate incubated for 3 hrs in presence of ATP by Kinase Glo luminescent ass...More data for this Ligand-Target Pair
Affinity DataIC50: 520nMAssay Description:Inhibition of recombinant full-length human aPKCzeta using CREBtide as substrate incubated for 3 hrs in presence of ATP by Kinase Glo luminescent ass...More data for this Ligand-Target Pair
Affinity DataIC50: 560nMAssay Description:Inhibition of recombinant full-length human aPKCzeta using CREBtide as substrate incubated for 3 hrs in presence of ATP by Kinase Glo luminescent ass...More data for this Ligand-Target Pair
Affinity DataIC50: 700nMAssay Description:Inhibition of recombinant full-length human aPKCzeta using CREBtide as substrate incubated for 3 hrs in presence of ATP by Kinase Glo luminescent ass...More data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Inhibition of atypical PKCzeta (unknown origin) using CREBtide as substrate incubated for 1 hr measured every 2.5 mins by ADP Quest assayMore data for this Ligand-Target Pair
Affinity DataIC50: 900nMAssay Description:Inhibition of atypical PKCiota (unknown origin) using CREBtide as substrate incubated for 1 hr measured every 2.5 mins by ADP Quest assayMore data for this Ligand-Target Pair
Affinity DataIC50: 900nMAssay Description:Inhibition of atypical PKCiota (unknown origin) using CREBtide as substrate incubated for 1 hr measured every 2.5 mins by ADP Quest assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:IC50 values were determined using an in vitro luminescence-based kinase assay against aPKCζ to elucidate a pharmacophore. The IC50 values determ...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Penn State University College Of Medicine
Curated by ChEMBL
Penn State University College Of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
Affinity DataIC50: 1.15E+3nMAssay Description:Inhibition of recombinant full-length human aPKCzeta using CREBtide as substrate incubated for 3 hrs in presence of ATP by Kinase Glo luminescent ass...More data for this Ligand-Target Pair
Affinity DataIC50: 1.64E+3nMAssay Description:Inhibition of recombinant full-length human aPKCzeta in presence of ATP at Km concentration by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:IC50 values were determined using an in vitro luminescence-based kinase assay against aPKCζ to elucidate a pharmacophore. The IC50 values determ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:IC50 values were determined using an in vitro luminescence-based kinase assay against aPKCζ to elucidate a pharmacophore. The IC50 values determ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of atypical PKCzeta (unknown origin) using CREBtide as substrate incubated for 1 hr measured every 2.5 mins by ADP Quest assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of atypical PKCiota (unknown origin) using CREBtide as substrate incubated for 1 hr measured every 2.5 mins by ADP Quest assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of atypical PKCzeta (unknown origin) using CREBtide as substrate incubated for 1 hr measured every 2.5 mins by ADP Quest assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of atypical PKCzeta (unknown origin) using CREBtide as substrate incubated for 1 hr measured every 2.5 mins by ADP Quest assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of recombinant full-length human aPKCzeta using CREBtide as substrate incubated for 3 hrs in presence of ATP by Kinase Glo luminescent ass...More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:IC50 values were determined using an in vitro luminescence-based kinase assay against aPKCζ to elucidate a pharmacophore. The IC50 values determ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of recombinant full-length human aPKCzeta expressed in Sf21 insect cells using 5FAM-ERMRPRKRQGSVRRRV-NH2 as substrate in presence of ATP a...More data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:IC50 values were determined using an in vitro luminescence-based kinase assay against aPKCζ to elucidate a pharmacophore. The IC50 values determ...More data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:IC50 values were determined using an in vitro luminescence-based kinase assay against aPKCζ to elucidate a pharmacophore. The IC50 values determ...More data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:IC50 values were determined using an in vitro luminescence-based kinase assay against aPKCζ to elucidate a pharmacophore. The IC50 values determ...More data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of atypical PKCzeta (unknown origin) using CREBtide as substrate incubated for 1 hr measured every 2.5 mins by ADP Quest assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.08E+3nMAssay Description:Inhibition of recombinant full-length human aPKCiota in presence of ATP at Km concentration by radiometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:IC50 values were determined using an in vitro luminescence-based kinase assay against aPKCζ to elucidate a pharmacophore. The IC50 values determ...More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:IC50 values were determined using an in vitro luminescence-based kinase assay against aPKCζ to elucidate a pharmacophore. The IC50 values determ...More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of atypical PKCiota (unknown origin) using CREBtide as substrate incubated for 1 hr measured every 2.5 mins by ADP Quest assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:IC50 values were determined using an in vitro luminescence-based kinase assay against aPKCζ to elucidate a pharmacophore. The IC50 values determ...More data for this Ligand-Target Pair
Affinity DataIC50: 6.00E+3nMAssay Description:IC50 values were determined using an in vitro luminescence-based kinase assay against aPKCζ to elucidate a pharmacophore. The IC50 values determ...More data for this Ligand-Target Pair
Affinity DataIC50: 6.00E+3nMAssay Description:IC50 values were determined using an in vitro luminescence-based kinase assay against aPKCζ to elucidate a pharmacophore. The IC50 values determ...More data for this Ligand-Target Pair
Affinity DataIC50: 6.00E+3nMAssay Description:IC50 values were determined using an in vitro luminescence-based kinase assay against aPKCζ to elucidate a pharmacophore. The IC50 values determ...More data for this Ligand-Target Pair
Affinity DataIC50: 6.00E+3nMAssay Description:IC50 values were determined using an in vitro luminescence-based kinase assay against aPKCζ to elucidate a pharmacophore. The IC50 values determ...More data for this Ligand-Target Pair
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of atypical PKCzeta (unknown origin) using CREBtide as substrate incubated for 1 hr measured every 2.5 mins by ADP Quest assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of atypical PKCzeta (unknown origin) using CREBtide as substrate incubated for 1 hr measured every 2.5 mins by ADP Quest assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.00E+3nMAssay Description:IC50 values were determined using an in vitro luminescence-based kinase assay against aPKCζ to elucidate a pharmacophore. The IC50 values determ...More data for this Ligand-Target Pair
Affinity DataIC50: 7.00E+3nMAssay Description:IC50 values were determined using an in vitro luminescence-based kinase assay against aPKCζ to elucidate a pharmacophore. The IC50 values determ...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Penn State University College Of Medicine
Curated by ChEMBL
Penn State University College Of Medicine
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Penn State University College Of Medicine
Curated by ChEMBL
Penn State University College Of Medicine
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Penn State University College Of Medicine
Curated by ChEMBL
Penn State University College Of Medicine
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+4nMAssay Description:IC50 values were determined using an in vitro luminescence-based kinase assay against aPKCζ to elucidate a pharmacophore. The IC50 values determ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.11E+4nMAssay Description:Inhibition of recombinant full-length human aPKCzeta using CREBtide as substrate incubated for 3 hrs in presence of ATP by Kinase Glo luminescent ass...More data for this Ligand-Target Pair
Affinity DataIC50: 1.62E+4nMAssay Description:Inhibition of recombinant full-length human aPKCzeta using CREBtide as substrate incubated for 3 hrs in presence of ATP by Kinase Glo luminescent ass...More data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+4nMAssay Description:IC50 values were determined using an in vitro luminescence-based kinase assay against aPKCζ to elucidate a pharmacophore. The IC50 values determ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:The IC50 values for PKCl-diMeO and compounds described herein and illustrated in FIG. 6 are described in Table 2. The IC50 values were determined usi...More data for this Ligand-Target Pair