Compile Data Set for Download or QSAR
maximum 50k data
Found 563 with Last Name = 'rueher' and Initial = 'd'
TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM224627(US9328070, 2)
Affinity DataKi:  15nMpH: 7.4Assay Description:For binding experiments, cDNA encoding human mGlu 5a receptor was transiently transfected into EBNA cells using a procedure described by Schlaeger an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Rattus norvegicus (Rat))
Hoffmann-La Roche

US Patent
LigandPNGBDBM143695(US9682959, 3 | US9751856, 3)
Affinity DataKi:  16nMAssay Description:The pharmacological activity of the compounds was tested using the following method: cDNA encoding rat mGlu 5a receptor was transiently transfected i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM143695(US9682959, 3 | US9751856, 3)
Affinity DataKi:  16nMAssay Description:cDNA encoding rat mGlu 5a receptor was transiently transfected into EBNA cells using a procedure described by E.-J. Schlaeger and K. Christensen (Cyt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM50071369(CHEMBL3410220)
Affinity DataKi:  17nMAssay Description:Displacement of [3H]MPEP from mGlu5 receptor (unknown origin) expressed in HEK293 cells by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Rattus norvegicus (Rat))
Hoffmann-La Roche

US Patent
LigandPNGBDBM143693(US9682959, 1 | US9751856, 1)
Affinity DataKi:  18nMAssay Description:The pharmacological activity of the compounds was tested using the following method: cDNA encoding rat mGlu 5a receptor was transiently transfected i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM50071328(CHEMBL3410213)
Affinity DataKi:  18nMAssay Description:Displacement of [3H]MPEP from mGlu5 receptor (unknown origin) expressed in HEK293 cells by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM143693(US9682959, 1 | US9751856, 1)
Affinity DataKi:  18nMAssay Description:cDNA encoding rat mGlu 5a receptor was transiently transfected into EBNA cells using a procedure described by E.-J. Schlaeger and K. Christensen (Cyt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM199988(US9227959, 2)
Affinity DataKi:  19nMpH: 7.4Assay Description:For binding experiments, cDNA encoding human mGlu 5a receptor was transiently transfected into EBNA cells using a procedure described by Schlaeger ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM50071375(CHEMBL3410223 | US10618900, No. CTEP)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]MPEP from mGlu5 receptor (unknown origin) expressed in HEK293 cells by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM50071372(CHEMBL1946770)
Affinity DataKi:  22nMAssay Description:Displacement of [3H]MPEP from mGlu5 receptor (unknown origin) expressed in HEK293 cells by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM199989(US9227959, 3)
Affinity DataKi:  23nMpH: 7.4Assay Description:For binding experiments, cDNA encoding human mGlu 5a receptor was transiently transfected into EBNA cells using a procedure described by Schlaeger ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM234211(US9359301, 2)
Affinity DataKi:  24nMpH: 7.4Assay Description:For binding experiments, cDNA encoding human mGlu 5a receptor was transiently transfected into EBNA cells using a procedure described by Schlaeger an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM224626(US9328070, 1)
Affinity DataKi:  28nMpH: 7.4Assay Description:For binding experiments, cDNA encoding human mGlu 5a receptor was transiently transfected into EBNA cells using a procedure described by Schlaeger an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM50071333(CHEMBL3410215)
Affinity DataKi:  28nMAssay Description:Displacement of [3H]MPEP from mGlu5 receptor (unknown origin) expressed in HEK293 cells by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM50071332(CHEMBL3410214)
Affinity DataKi:  29nMAssay Description:Displacement of [3H]MPEP from mGlu5 receptor (unknown origin) expressed in HEK293 cells by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM224623(US9328070, Reference compound 1 | US9359301, Refer...)
Affinity DataKi:  29nMpH: 7.4Assay Description:For binding experiments, cDNA encoding human mGlu 5a receptor was transiently transfected into EBNA cells using a procedure described by Schlaeger an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM224623(US9328070, Reference compound 1 | US9359301, Refer...)
Affinity DataKi:  29nMpH: 7.4Assay Description:For binding experiments, cDNA encoding human mGlu 5a receptor was transiently transfected into EBNA cells using a procedure described by Schlaeger an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM50071371(CHEMBL3410221)
Affinity DataKi:  32nMAssay Description:Displacement of [3H]MPEP from mGlu5 receptor (unknown origin) expressed in HEK293 cells by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM50071376(CHEMBL3410224)
Affinity DataKi:  33nMAssay Description:Displacement of [3H]MPEP from mGlu5 receptor (unknown origin) expressed in HEK293 cells by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM50071374(Basimglurant | RG-7090 | RO-4917523)
Affinity DataKi:  36nMAssay Description:Displacement of [3H]MPEP from mGlu5 receptor (unknown origin) expressed in HEK293 cells by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Rattus norvegicus (Rat))
Hoffmann-La Roche

US Patent
LigandPNGBDBM143694(US9682959, 2 | US9751856, 2)
Affinity DataKi:  38nMAssay Description:The pharmacological activity of the compounds was tested using the following method: cDNA encoding rat mGlu 5a receptor was transiently transfected i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM143694(US9682959, 2 | US9751856, 2)
Affinity DataKi:  38nMAssay Description:cDNA encoding rat mGlu 5a receptor was transiently transfected into EBNA cells using a procedure described by E.-J. Schlaeger and K. Christensen (Cyt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM234210(US9359301, 1)
Affinity DataKi:  42nMpH: 7.4Assay Description:For binding experiments, cDNA encoding human mGlu 5a receptor was transiently transfected into EBNA cells using a procedure described by Schlaeger an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM224624(US9328070, Reference compound 2)
Affinity DataKi:  42nMpH: 7.4Assay Description:For binding experiments, cDNA encoding human mGlu 5a receptor was transiently transfected into EBNA cells using a procedure described by Schlaeger an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM234213(US9359301, 4)
Affinity DataKi:  46nMpH: 7.4Assay Description:For binding experiments, cDNA encoding human mGlu 5a receptor was transiently transfected into EBNA cells using a procedure described by Schlaeger an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM234209(US9359301, Reference compound 2)
Affinity DataKi:  51nMpH: 7.4Assay Description:For binding experiments, cDNA encoding human mGlu 5a receptor was transiently transfected into EBNA cells using a procedure described by Schlaeger an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM224625(US9328070, Reference compound 3)
Affinity DataKi:  58nMpH: 7.4Assay Description:For binding experiments, cDNA encoding human mGlu 5a receptor was transiently transfected into EBNA cells using a procedure described by Schlaeger an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM199990(US9227959, 4)
Affinity DataKi:  67nMpH: 7.4Assay Description:For binding experiments, cDNA encoding human mGlu 5a receptor was transiently transfected into EBNA cells using a procedure described by Schlaeger ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM50071324(CHEMBL3410207)
Affinity DataKi:  69nMAssay Description:Displacement of [3H]MPEP from mGlu5 receptor (unknown origin) expressed in HEK293 cells by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM50071322(CHEMBL3410209)
Affinity DataKi:  72nMAssay Description:Displacement of [3H]MPEP from mGlu5 receptor (unknown origin) expressed in HEK293 cells by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM199987(US9227959, 1)
Affinity DataKi:  72nMpH: 7.4Assay Description:For binding experiments, cDNA encoding human mGlu 5a receptor was transiently transfected into EBNA cells using a procedure described by Schlaeger ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Rattus norvegicus (Rat))
Hoffmann-La Roche

US Patent
LigandPNGBDBM143697(US9682959, 4 | US9751856, 4)
Affinity DataKi:  80nMAssay Description:The pharmacological activity of the compounds was tested using the following method: cDNA encoding rat mGlu 5a receptor was transiently transfected i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM143697(US9682959, 4 | US9751856, 4)
Affinity DataKi:  80nMAssay Description:cDNA encoding rat mGlu 5a receptor was transiently transfected into EBNA cells using a procedure described by E.-J. Schlaeger and K. Christensen (Cyt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM50071335(CHEMBL3410217)
Affinity DataKi:  83nMAssay Description:Displacement of [3H]MPEP from mGlu5 receptor (unknown origin) expressed in HEK293 cells by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM50071334(CHEMBL3410216)
Affinity DataKi:  90nMAssay Description:Displacement of [3H]MPEP from mGlu5 receptor (unknown origin) expressed in HEK293 cells by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM234212(US9359301, 3)
Affinity DataKi:  94nMpH: 7.4Assay Description:For binding experiments, cDNA encoding human mGlu 5a receptor was transiently transfected into EBNA cells using a procedure described by Schlaeger an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM199985(US9227959, Reference Compound 1, Ex. 35)
Affinity DataKi:  201nMpH: 7.4Assay Description:For binding experiments, cDNA encoding human mGlu 5a receptor was transiently transfected into EBNA cells using a procedure described by Schlaeger ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM50071326(CHEMBL3410211)
Affinity DataKi:  213nMAssay Description:Displacement of [3H]MPEP from mGlu5 receptor (unknown origin) expressed in HEK293 cells by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM50071367(CHEMBL3410218)
Affinity DataKi:  252nMAssay Description:Displacement of [3H]MPEP from mGlu5 receptor (unknown origin) expressed in HEK293 cells by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM50071327(CHEMBL3410212)
Affinity DataKi:  255nMAssay Description:Displacement of [3H]MPEP from mGlu5 receptor (unknown origin) expressed in HEK293 cells by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Rattus norvegicus (Rat))
Hoffmann-La Roche

US Patent
LigandPNGBDBM143699(US9682959, 6 | US9751856, 6)
Affinity DataKi:  280nMAssay Description:The pharmacological activity of the compounds was tested using the following method: cDNA encoding rat mGlu 5a receptor was transiently transfected i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM143699(US9682959, 6 | US9751856, 6)
Affinity DataKi:  280nMAssay Description:cDNA encoding rat mGlu 5a receptor was transiently transfected into EBNA cells using a procedure described by E.-J. Schlaeger and K. Christensen (Cyt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM143698(US9682959, 5 | US9751856, 5)
Affinity DataKi:  281nMAssay Description:cDNA encoding rat mGlu 5a receptor was transiently transfected into EBNA cells using a procedure described by E.-J. Schlaeger and K. Christensen (Cyt...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Rattus norvegicus (Rat))
Hoffmann-La Roche

US Patent
LigandPNGBDBM143698(US9682959, 5 | US9751856, 5)
Affinity DataKi:  281nMAssay Description:The pharmacological activity of the compounds was tested using the following method: cDNA encoding rat mGlu 5a receptor was transiently transfected i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform 1 of Metabotropic glutamate receptor 5 (5a)(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM199986(US9227959, Reference Compound 2, Ex. 46)
Affinity DataKi:  315nMpH: 7.4Assay Description:For binding experiments, cDNA encoding human mGlu 5a receptor was transiently transfected into EBNA cells using a procedure described by Schlaeger ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM50071377(CHEMBL3407528)
Affinity DataKi:  368nMAssay Description:Displacement of [3H]MPEP from mGlu5 receptor (unknown origin) expressed in HEK293 cells by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM50071378(CHEMBL3410225)
Affinity DataKi:  559nMAssay Description:Displacement of [3H]MPEP from mGlu5 receptor (unknown origin) expressed in HEK293 cells by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM50071368(CHEMBL3410219)
Affinity DataKi:  567nMAssay Description:Displacement of [3H]MPEP from mGlu5 receptor (unknown origin) expressed in HEK293 cells by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM50071373(CHEMBL3410222)
Affinity DataKi:  1.44E+3nMAssay Description:Displacement of [3H]MPEP from mGlu5 receptor (unknown origin) expressed in HEK293 cells by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM50071323(CHEMBL3410208)
Affinity DataKi:  1.77E+3nMAssay Description:Displacement of [3H]MPEP from mGlu5 receptor (unknown origin) expressed in HEK293 cells by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 563 total ) | Next | Last >>
Jump to: