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Found 38 Enz. Inhib. hit(s) with all data for entry = 6703
TargetMu-type opioid receptor(Homo sapiens (Human))
Alkermes

US Patent
LigandPNGBDBM148986(US8962646, 8)
Affinity DataKi:  0.150nM ΔG°:  -56.1kJ/molepH: 7.5 T: 2°CAssay Description:Receptor Binding (in vitro Assay) The Ki (binding affinity) for mu-, delta-, and kippa-receptors was determined with a previously described method us...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Alkermes

US Patent
LigandPNGBDBM148977(US10512644, Compound Morphine | US8962646, A)
Affinity DataKi:  0.320nM ΔG°:  -54.2kJ/molepH: 7.5 T: 2°CAssay Description:Receptor Binding (in vitro Assay) The Ki (binding affinity) for mu-, delta-, and kippa-receptors was determined with a previously described method us...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Alkermes

US Patent
LigandPNGBDBM148978(US8962646, B)
Affinity DataKi:  0.390nM ΔG°:  -53.7kJ/molepH: 7.5 T: 2°CAssay Description:Receptor Binding (in vitro Assay) The Ki (binding affinity) for mu-, delta-, and kippa-receptors was determined with a previously described method us...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Alkermes

US Patent
LigandPNGBDBM148988(US8962646, 10)
Affinity DataKi:  0.430nM ΔG°:  -53.5kJ/molepH: 7.5 T: 2°CAssay Description:Receptor Binding (in vitro Assay) The Ki (binding affinity) for mu-, delta-, and kippa-receptors was determined with a previously described method us...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Alkermes

US Patent
LigandPNGBDBM148985(US8962646, 7)
Affinity DataKi:  0.520nM ΔG°:  -53.0kJ/molepH: 7.5 T: 2°CAssay Description:Receptor Binding (in vitro Assay) The Ki (binding affinity) for mu-, delta-, and kippa-receptors was determined with a previously described method us...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Alkermes

US Patent
LigandPNGBDBM148981(US8962646, 3)
Affinity DataKi:  0.630nM ΔG°:  -52.5kJ/molepH: 7.5 T: 2°CAssay Description:Receptor Binding (in vitro Assay) The Ki (binding affinity) for mu-, delta-, and kippa-receptors was determined with a previously described method us...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Alkermes

US Patent
LigandPNGBDBM148980(US8962646, 2)
Affinity DataKi:  0.660nM ΔG°:  -52.4kJ/molepH: 7.5 T: 2°CAssay Description:Receptor Binding (in vitro Assay) The Ki (binding affinity) for mu-, delta-, and kippa-receptors was determined with a previously described method us...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
Alkermes

US Patent
LigandPNGBDBM148978(US8962646, B)
Affinity DataKi:  0.710nM ΔG°:  -52.2kJ/molepH: 7.5 T: 2°CAssay Description:Receptor Binding (in vitro Assay) The Ki (binding affinity) for mu-, delta-, and kippa-receptors was determined with a previously described method us...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Alkermes

US Patent
LigandPNGBDBM148982(US8962646, 4)
Affinity DataKi:  1.30nM ΔG°:  -50.7kJ/molepH: 7.5 T: 2°CAssay Description:Receptor Binding (in vitro Assay) The Ki (binding affinity) for mu-, delta-, and kippa-receptors was determined with a previously described method us...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Alkermes

US Patent
LigandPNGBDBM148989(US8962646, 11)
Affinity DataKi:  1.60nM ΔG°:  -50.2kJ/molepH: 7.5 T: 2°CAssay Description:Receptor Binding (in vitro Assay) The Ki (binding affinity) for mu-, delta-, and kippa-receptors was determined with a previously described method us...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Alkermes

US Patent
LigandPNGBDBM148987(US8962646, 9)
Affinity DataKi:  1.70nM ΔG°:  -50.1kJ/molepH: 7.5 T: 2°CAssay Description:Receptor Binding (in vitro Assay) The Ki (binding affinity) for mu-, delta-, and kippa-receptors was determined with a previously described method us...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Alkermes

US Patent
LigandPNGBDBM148983(US8962646, 5)
Affinity DataKi:  1.70nM ΔG°:  -50.1kJ/molepH: 7.5 T: 2°CAssay Description:Receptor Binding (in vitro Assay) The Ki (binding affinity) for mu-, delta-, and kippa-receptors was determined with a previously described method us...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDelta-type opioid receptor(Homo sapiens (Human))
Alkermes

US Patent
LigandPNGBDBM148986(US8962646, 8)
Affinity DataKi:  2.10nM ΔG°:  -49.5kJ/molepH: 7.5 T: 2°CAssay Description:Receptor Binding (in vitro Assay) The Ki (binding affinity) for mu-, delta-, and kippa-receptors was determined with a previously described method us...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Alkermes

US Patent
LigandPNGBDBM148984(US8962646, 6)
Affinity DataKi:  3.5nM ΔG°:  -48.3kJ/molepH: 7.5 T: 2°CAssay Description:Receptor Binding (in vitro Assay) The Ki (binding affinity) for mu-, delta-, and kippa-receptors was determined with a previously described method us...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDelta-type opioid receptor(Homo sapiens (Human))
Alkermes

US Patent
LigandPNGBDBM148978(US8962646, B)
Affinity DataKi:  5.40nM ΔG°:  -47.2kJ/molepH: 7.5 T: 2°CAssay Description:Receptor Binding (in vitro Assay) The Ki (binding affinity) for mu-, delta-, and kippa-receptors was determined with a previously described method us...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDelta-type opioid receptor(Homo sapiens (Human))
Alkermes

US Patent
LigandPNGBDBM148988(US8962646, 10)
Affinity DataKi:  10nM ΔG°:  -45.7kJ/molepH: 7.5 T: 2°CAssay Description:Receptor Binding (in vitro Assay) The Ki (binding affinity) for mu-, delta-, and kippa-receptors was determined with a previously described method us...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDelta-type opioid receptor(Homo sapiens (Human))
Alkermes

US Patent
LigandPNGBDBM148977(US10512644, Compound Morphine | US8962646, A)
Affinity DataKi:  11nM ΔG°:  -45.4kJ/molepH: 7.5 T: 2°CAssay Description:Receptor Binding (in vitro Assay) The Ki (binding affinity) for mu-, delta-, and kippa-receptors was determined with a previously described method us...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDelta-type opioid receptor(Homo sapiens (Human))
Alkermes

US Patent
LigandPNGBDBM148981(US8962646, 3)
Affinity DataKi:  17nM ΔG°:  -44.3kJ/molepH: 7.5 T: 2°CAssay Description:Receptor Binding (in vitro Assay) The Ki (binding affinity) for mu-, delta-, and kippa-receptors was determined with a previously described method us...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
Alkermes

US Patent
LigandPNGBDBM148986(US8962646, 8)
Affinity DataKi:  19nM ΔG°:  -44.1kJ/molepH: 7.5 T: 2°CAssay Description:Receptor Binding (in vitro Assay) The Ki (binding affinity) for mu-, delta-, and kippa-receptors was determined with a previously described method us...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDelta-type opioid receptor(Homo sapiens (Human))
Alkermes

US Patent
LigandPNGBDBM148980(US8962646, 2)
Affinity DataKi:  24nM ΔG°:  -43.5kJ/molepH: 7.5 T: 2°CAssay Description:Receptor Binding (in vitro Assay) The Ki (binding affinity) for mu-, delta-, and kippa-receptors was determined with a previously described method us...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Alkermes

US Patent
LigandPNGBDBM148979(US8962646, 1)
Affinity DataKi:  27nM ΔG°:  -43.2kJ/molepH: 7.5 T: 2°CAssay Description:Receptor Binding (in vitro Assay) The Ki (binding affinity) for mu-, delta-, and kippa-receptors was determined with a previously described method us...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDelta-type opioid receptor(Homo sapiens (Human))
Alkermes

US Patent
LigandPNGBDBM148985(US8962646, 7)
Affinity DataKi:  42nM ΔG°:  -42.1kJ/molepH: 7.5 T: 2°CAssay Description:Receptor Binding (in vitro Assay) The Ki (binding affinity) for mu-, delta-, and kippa-receptors was determined with a previously described method us...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDelta-type opioid receptor(Homo sapiens (Human))
Alkermes

US Patent
LigandPNGBDBM148983(US8962646, 5)
Affinity DataKi:  51nM ΔG°:  -41.6kJ/molepH: 7.5 T: 2°CAssay Description:Receptor Binding (in vitro Assay) The Ki (binding affinity) for mu-, delta-, and kippa-receptors was determined with a previously described method us...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDelta-type opioid receptor(Homo sapiens (Human))
Alkermes

US Patent
LigandPNGBDBM148984(US8962646, 6)
Affinity DataKi:  97nM ΔG°:  -40.0kJ/molepH: 7.5 T: 2°CAssay Description:Receptor Binding (in vitro Assay) The Ki (binding affinity) for mu-, delta-, and kippa-receptors was determined with a previously described method us...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
Alkermes

US Patent
LigandPNGBDBM148988(US8962646, 10)
Affinity DataKi:  140nM ΔG°:  -39.1kJ/molepH: 7.5 T: 2°CAssay Description:Receptor Binding (in vitro Assay) The Ki (binding affinity) for mu-, delta-, and kippa-receptors was determined with a previously described method us...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
Alkermes

US Patent
LigandPNGBDBM148981(US8962646, 3)
Affinity DataKi:  180nM ΔG°:  -38.5kJ/molepH: 7.5 T: 2°CAssay Description:Receptor Binding (in vitro Assay) The Ki (binding affinity) for mu-, delta-, and kippa-receptors was determined with a previously described method us...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
Alkermes

US Patent
LigandPNGBDBM148982(US8962646, 4)
Affinity DataKi:  190nM ΔG°:  -38.4kJ/molepH: 7.5 T: 2°CAssay Description:Receptor Binding (in vitro Assay) The Ki (binding affinity) for mu-, delta-, and kippa-receptors was determined with a previously described method us...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
Alkermes

US Patent
LigandPNGBDBM148977(US10512644, Compound Morphine | US8962646, A)
Affinity DataKi:  230nM ΔG°:  -37.9kJ/molepH: 7.5 T: 2°CAssay Description:Receptor Binding (in vitro Assay) The Ki (binding affinity) for mu-, delta-, and kippa-receptors was determined with a previously described method us...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDelta-type opioid receptor(Homo sapiens (Human))
Alkermes

US Patent
LigandPNGBDBM148987(US8962646, 9)
Affinity DataKi:  280nM ΔG°:  -37.4kJ/molepH: 7.5 T: 2°CAssay Description:Receptor Binding (in vitro Assay) The Ki (binding affinity) for mu-, delta-, and kippa-receptors was determined with a previously described method us...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
Alkermes

US Patent
LigandPNGBDBM148987(US8962646, 9)
Affinity DataKi:  400nM ΔG°:  -36.5kJ/molepH: 7.5 T: 2°CAssay Description:Receptor Binding (in vitro Assay) The Ki (binding affinity) for mu-, delta-, and kippa-receptors was determined with a previously described method us...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDelta-type opioid receptor(Homo sapiens (Human))
Alkermes

US Patent
LigandPNGBDBM148979(US8962646, 1)
Affinity DataKi:  490nM ΔG°:  -36.0kJ/molepH: 7.5 T: 2°CAssay Description:Receptor Binding (in vitro Assay) The Ki (binding affinity) for mu-, delta-, and kippa-receptors was determined with a previously described method us...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
Alkermes

US Patent
LigandPNGBDBM148983(US8962646, 5)
Affinity DataKi:  680nM ΔG°:  -35.2kJ/molepH: 7.5 T: 2°CAssay Description:Receptor Binding (in vitro Assay) The Ki (binding affinity) for mu-, delta-, and kippa-receptors was determined with a previously described method us...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
Alkermes

US Patent
LigandPNGBDBM148979(US8962646, 1)
Affinity DataKi:  850nM ΔG°:  -34.6kJ/molepH: 7.5 T: 2°CAssay Description:Receptor Binding (in vitro Assay) The Ki (binding affinity) for mu-, delta-, and kippa-receptors was determined with a previously described method us...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
Alkermes

US Patent
LigandPNGBDBM148985(US8962646, 7)
Affinity DataKi:  860nM ΔG°:  -34.6kJ/molepH: 7.5 T: 2°CAssay Description:Receptor Binding (in vitro Assay) The Ki (binding affinity) for mu-, delta-, and kippa-receptors was determined with a previously described method us...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDelta-type opioid receptor(Homo sapiens (Human))
Alkermes

US Patent
LigandPNGBDBM148989(US8962646, 11)
Affinity DataKi: >1.00E+3nM ΔG°: >-34.2kJ/molepH: 7.5 T: 2°CAssay Description:Receptor Binding (in vitro Assay) The Ki (binding affinity) for mu-, delta-, and kippa-receptors was determined with a previously described method us...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
Alkermes

US Patent
LigandPNGBDBM148980(US8962646, 2)
Affinity DataKi: >1.00E+3nM ΔG°: >-34.2kJ/molepH: 7.5 T: 2°CAssay Description:Receptor Binding (in vitro Assay) The Ki (binding affinity) for mu-, delta-, and kippa-receptors was determined with a previously described method us...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDelta-type opioid receptor(Homo sapiens (Human))
Alkermes

US Patent
LigandPNGBDBM148982(US8962646, 4)
Affinity DataKi: >1.00E+3nM ΔG°: >-34.2kJ/molepH: 7.5 T: 2°CAssay Description:Receptor Binding (in vitro Assay) The Ki (binding affinity) for mu-, delta-, and kippa-receptors was determined with a previously described method us...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
Alkermes

US Patent
LigandPNGBDBM148984(US8962646, 6)
Affinity DataKi:  1.00E+3nM ΔG°:  -34.2kJ/molepH: 7.5 T: 2°CAssay Description:Receptor Binding (in vitro Assay) The Ki (binding affinity) for mu-, delta-, and kippa-receptors was determined with a previously described method us...More data for this Ligand-Target Pair
In DepthDetails US Patent