Compile Data Set for Download or QSAR
Found 48 Enz. Inhib. hit(s) with all data for entry = 50012314
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Utrecht University

Curated by ChEMBL
LigandPNGBDBM22988((5Z,8Z,11Z,14Z)-N-(2-hydroxyethyl)icosa-5,8,11,14-...)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)NCCO
Show InChI InChI=1S/C22H37NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-22(25)23-20-21-24/h6-7,9-10,12-13,15-16,24H,2-5,8,11,14,17-21H2,1H3,(H,23,25)/b7-6-,10-9-,13-12-,16-15-
Affinity DataKi:  90nMAssay Description:Displacement of [3H]-CP-55,940 from rat forebrain membrane which expresses Cannabinoid receptor 1 in the presence of PMSFMore data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Utrecht University

Curated by ChEMBL
LigandPNGBDBM26144(1,3-dihydroxypropan-2-yl (5Z,8Z,11Z,14Z)-icosa-5,8...)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)OC(CO)CO
Show InChI InChI=1S/C23H38O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-23(26)27-22(20-24)21-25/h6-7,9-10,12-13,15-16,22,24-25H,2-5,8,11,14,17-21H2,1H3/b7-6-,10-9-,13-12-,16-15-
Affinity DataKi:  100nMAssay Description:Displacement of [3H]-CP-55,940 from rat forebrain membrane which expresses Cannabinoid receptor 2 in the presence of PMSFMore data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Utrecht University

Curated by ChEMBL
LigandPNGBDBM26144(1,3-dihydroxypropan-2-yl (5Z,8Z,11Z,14Z)-icosa-5,8...)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)OC(CO)CO
Show InChI InChI=1S/C23H38O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-23(26)27-22(20-24)21-25/h6-7,9-10,12-13,15-16,22,24-25H,2-5,8,11,14,17-21H2,1H3/b7-6-,10-9-,13-12-,16-15-
Affinity DataKi:  100nMAssay Description:Displacement of [3H]-CP-55,940 from rat forebrain membrane which expresses Cannabinoid receptor 1 in the presence of PMSFMore data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Utrecht University

Curated by ChEMBL
LigandPNGBDBM50117245(12-Hydroxy-icosa-5,8,10,14-tetraenoic acid (2-hydr...)
Show SMILES CCCCC\C=C/C[C@@H](O)\C=C\C=C/C\C=C/CCCC(=O)NCCO
Show InChI InChI=1S/C22H37NO3/c1-2-3-4-5-10-13-16-21(25)17-14-11-8-6-7-9-12-15-18-22(26)23-19-20-24/h7-11,13-14,17,21,24-25H,2-6,12,15-16,18-20H2,1H3,(H,23,26)/b9-7-,11-8-,13-10-,17-14+/t21-/m1/s1
Affinity DataKi:  150nMAssay Description:Displacement of [3H]-CP-55,940 from rat forebrain membrane which expresses Cannabinoid receptor 1 in the presence of PMSFMore data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Utrecht University

Curated by ChEMBL
LigandPNGBDBM22988((5Z,8Z,11Z,14Z)-N-(2-hydroxyethyl)icosa-5,8,11,14-...)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)NCCO
Show InChI InChI=1S/C22H37NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-22(25)23-20-21-24/h6-7,9-10,12-13,15-16,24H,2-5,8,11,14,17-21H2,1H3,(H,23,25)/b7-6-,10-9-,13-12-,16-15-
Affinity DataKi:  360nMAssay Description:Displacement of [3H]-CP-55,940 from rat forebrain membrane which expresses Cannabinoid receptor 2 in the presence of PMSFMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Utrecht University

Curated by ChEMBL
LigandPNGBDBM50117251(13-Hydroxy-octadeca-9,11-dienoic acid (2-hydroxy-e...)
Show SMILES CCCCC[C@H](O)\C=C\C=C/CCCCCCCC(=O)NCCO
Show InChI InChI=1S/C20H37NO3/c1-2-3-11-14-19(23)15-12-9-7-5-4-6-8-10-13-16-20(24)21-17-18-22/h7,9,12,15,19,22-23H,2-6,8,10-11,13-14,16-18H2,1H3,(H,21,24)/b9-7-,15-12+/t19-/m0/s1
Affinity DataKi:  430nMAssay Description:Inhibition of Fatty-acid amide hydrolase (FAAH) activity in human lymphoma U937 cell using [3H]-AEA as substrate in the 0-25 uM concMore data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Utrecht University

Curated by ChEMBL
LigandPNGBDBM50117245(12-Hydroxy-icosa-5,8,10,14-tetraenoic acid (2-hydr...)
Show SMILES CCCCC\C=C/C[C@@H](O)\C=C\C=C/C\C=C/CCCC(=O)NCCO
Show InChI InChI=1S/C22H37NO3/c1-2-3-4-5-10-13-16-21(25)17-14-11-8-6-7-9-12-15-18-22(26)23-19-20-24/h7-11,13-14,17,21,24-25H,2-6,12,15-16,18-20H2,1H3,(H,23,26)/b9-7-,11-8-,13-10-,17-14+/t21-/m1/s1
Affinity DataKi:  500nMAssay Description:Displacement of [3H]-CP-55,940 from rat forebrain membrane which expresses Cannabinoid receptor 2 in the presence of PMSFMore data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Utrecht University

Curated by ChEMBL
LigandPNGBDBM50117256(15-Hydroxy-icosa-5,8,11,13-tetraenoic acid 2,3-dih...)
Show SMILES CCCCC[C@H](O)\C=C\C=C/C\C=C/C\C=C/CCCC(=O)OC[C@@H](O)CO
Show InChI InChI=1S/C23H38O5/c1-2-3-13-16-21(25)17-14-11-9-7-5-4-6-8-10-12-15-18-23(27)28-20-22(26)19-24/h4-5,8-11,14,17,21-22,24-26H,2-3,6-7,12-13,15-16,18-20H2,1H3/b5-4-,10-8-,11-9-,17-14+/t21-,22-/m0/s1
Affinity DataKi:  550nMAssay Description:Displacement of [3H]-CP-55,940 from rat forebrain membrane which expresses Cannabinoid receptor 2 in the presence of PMSFMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Utrecht University

Curated by ChEMBL
LigandPNGBDBM50117247(11-Hydroxy-icosa-5,8,12,14-tetraenoic acid (2-hydr...)
Show SMILES CCCCC\C=C/C=C/[C@@H](O)C\C=C/C\C=C/CCCC(=O)NCCO
Show InChI InChI=1S/C22H37NO3/c1-2-3-4-5-7-10-13-16-21(25)17-14-11-8-6-9-12-15-18-22(26)23-19-20-24/h6-7,9-11,13-14,16,21,24-25H,2-5,8,12,15,17-20H2,1H3,(H,23,26)/b9-6-,10-7-,14-11-,16-13+/t21-/m1/s1
Affinity DataKi:  570nMAssay Description:Inhibition of Fatty-acid amide hydrolase (FAAH) activity in human lymphoma U937 cell using [3H]-AEA as substrate in the 0-25 uM concMore data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Utrecht University

Curated by ChEMBL
LigandPNGBDBM50117251(13-Hydroxy-octadeca-9,11-dienoic acid (2-hydroxy-e...)
Show SMILES CCCCC[C@H](O)\C=C\C=C/CCCCCCCC(=O)NCCO
Show InChI InChI=1S/C20H37NO3/c1-2-3-11-14-19(23)15-12-9-7-5-4-6-8-10-13-16-20(24)21-17-18-22/h7,9,12,15,19,22-23H,2-6,8,10-11,13-14,16-18H2,1H3,(H,21,24)/b9-7-,15-12+/t19-/m0/s1
Affinity DataKi:  600nMAssay Description:Displacement of [3H]-CP-55,940 from rat forebrain membrane which expresses Cannabinoid receptor 2 in the presence of PMSFMore data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Utrecht University

Curated by ChEMBL
LigandPNGBDBM50117252(15-Hydroxy-icosa-5,8,11,13-tetraenoic acid (2-hydr...)
Show SMILES CCCCC[C@@H](O)\C=C\C=C/C\C=C/C\C=C/CCCC(=O)NCCO
Show InChI InChI=1S/C22H37NO3/c1-2-3-13-16-21(25)17-14-11-9-7-5-4-6-8-10-12-15-18-22(26)23-19-20-24/h4-5,8-11,14,17,21,24-25H,2-3,6-7,12-13,15-16,18-20H2,1H3,(H,23,26)/b5-4-,10-8-,11-9-,17-14+/t21-/m1/s1
Affinity DataKi:  600nMAssay Description:Displacement of [3H]-CP-55,940 from rat forebrain membrane which expresses Cannabinoid receptor 1 in the presence of PMSFMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Utrecht University

Curated by ChEMBL
LigandPNGBDBM50117252(15-Hydroxy-icosa-5,8,11,13-tetraenoic acid (2-hydr...)
Show SMILES CCCCC[C@@H](O)\C=C\C=C/C\C=C/C\C=C/CCCC(=O)NCCO
Show InChI InChI=1S/C22H37NO3/c1-2-3-13-16-21(25)17-14-11-9-7-5-4-6-8-10-12-15-18-22(26)23-19-20-24/h4-5,8-11,14,17,21,24-25H,2-3,6-7,12-13,15-16,18-20H2,1H3,(H,23,26)/b5-4-,10-8-,11-9-,17-14+/t21-/m1/s1
Affinity DataKi:  630nMAssay Description:Inhibition of Fatty-acid amide hydrolase (FAAH) activity in human lymphoma U937 cell using [3H]-AEA as substrate in the 0-25 uM concMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Utrecht University

Curated by ChEMBL
LigandPNGBDBM50117250(15-Hydroxy-icosa-5,8,11,13-tetraenoic acid (2-hydr...)
Show SMILES CCCCCC(O)\C=C\C=C/C\C=C/C\C=C/CCCC(=O)NCCO
Show InChI InChI=1S/C22H37NO3/c1-2-3-13-16-21(25)17-14-11-9-7-5-4-6-8-10-12-15-18-22(26)23-19-20-24/h4-5,8-11,14,17,21,24-25H,2-3,6-7,12-13,15-16,18-20H2,1H3,(H,23,26)/b5-4-,10-8-,11-9-,17-14+
Affinity DataKi:  630nMAssay Description:Inhibition of Fatty-acid amide hydrolase (FAAH) activity in human lymphoma U937 cell using [3H]-AEA as substrate in the 0-25 uM concMore data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Utrecht University

Curated by ChEMBL
LigandPNGBDBM50117255(5-Hydroxy-icosa-6,8,11,14-tetraenoic acid (2-hydro...)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C=C/[C@@H](O)CCCC(=O)NCCO
Show InChI InChI=1S/C22H37NO3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-16-21(25)17-15-18-22(26)23-19-20-24/h6-7,9-10,12-14,16,21,24-25H,2-5,8,11,15,17-20H2,1H3,(H,23,26)/b7-6-,10-9-,13-12-,16-14+/t21-/m1/s1
Affinity DataKi:  680nMAssay Description:Displacement of [3H]-CP-55,940 from rat forebrain membrane which expresses Cannabinoid receptor 1 in the presence of PMSFMore data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Utrecht University

Curated by ChEMBL
LigandPNGBDBM50117250(15-Hydroxy-icosa-5,8,11,13-tetraenoic acid (2-hydr...)
Show SMILES CCCCCC(O)\C=C\C=C/C\C=C/C\C=C/CCCC(=O)NCCO
Show InChI InChI=1S/C22H37NO3/c1-2-3-13-16-21(25)17-14-11-9-7-5-4-6-8-10-12-15-18-22(26)23-19-20-24/h4-5,8-11,14,17,21,24-25H,2-3,6-7,12-13,15-16,18-20H2,1H3,(H,23,26)/b5-4-,10-8-,11-9-,17-14+
Affinity DataKi:  680nMAssay Description:Displacement of [3H]-CP-55,940 from rat forebrain membrane which expresses Cannabinoid receptor 1 in the presence of PMSFMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Utrecht University

Curated by ChEMBL
LigandPNGBDBM50117243(8,15-Dihydroxy-icosa-5,9,11,13-tetraenoic acid (2-...)
Show SMILES CCCCC[C@H](O)\C=C\C=C/C=C/[C@@H](O)C\C=C/CCCC(=O)NCCO
Show InChI InChI=1S/C22H37NO4/c1-2-3-8-13-20(25)14-9-4-5-10-15-21(26)16-11-6-7-12-17-22(27)23-18-19-24/h4-6,9-11,14-15,20-21,24-26H,2-3,7-8,12-13,16-19H2,1H3,(H,23,27)/b5-4-,11-6-,14-9+,15-10+/t20-,21+/m0/s1
Affinity DataKi:  690nMAssay Description:Inhibition of Fatty-acid amide hydrolase (FAAH) activity in human lymphoma U937 cell using [3H]-AEA as substrate in the 0-25 uM concMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Utrecht University

Curated by ChEMBL
LigandPNGBDBM50117254(11-Hydroxy-icosa-5,8,12,14-tetraenoic acid (2-hydr...)
Show SMILES CCCCC\C=C/C=C/C(O)C\C=C/C\C=C/CCCC(=O)NCCO
Show InChI InChI=1S/C22H37NO3/c1-2-3-4-5-7-10-13-16-21(25)17-14-11-8-6-9-12-15-18-22(26)23-19-20-24/h6-7,9-11,13-14,16,21,24-25H,2-5,8,12,15,17-20H2,1H3,(H,23,26)/b9-6-,10-7-,14-11-,16-13+
Affinity DataKi:  690nMAssay Description:Inhibition of Fatty-acid amide hydrolase (FAAH) activity in human lymphoma U937 cell using [3H]-AEA as substrate in the 0-25 uM concMore data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Utrecht University

Curated by ChEMBL
LigandPNGBDBM50117255(5-Hydroxy-icosa-6,8,11,14-tetraenoic acid (2-hydro...)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C=C/[C@@H](O)CCCC(=O)NCCO
Show InChI InChI=1S/C22H37NO3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-16-21(25)17-15-18-22(26)23-19-20-24/h6-7,9-10,12-14,16,21,24-25H,2-5,8,11,15,17-20H2,1H3,(H,23,26)/b7-6-,10-9-,13-12-,16-14+/t21-/m1/s1
Affinity DataKi:  710nMAssay Description:Displacement of [3H]-CP-55,940 from rat forebrain membrane which expresses Cannabinoid receptor 2 in the presence of PMSFMore data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Utrecht University

Curated by ChEMBL
LigandPNGBDBM50117254(11-Hydroxy-icosa-5,8,12,14-tetraenoic acid (2-hydr...)
Show SMILES CCCCC\C=C/C=C/C(O)C\C=C/C\C=C/CCCC(=O)NCCO
Show InChI InChI=1S/C22H37NO3/c1-2-3-4-5-7-10-13-16-21(25)17-14-11-8-6-9-12-15-18-22(26)23-19-20-24/h6-7,9-11,13-14,16,21,24-25H,2-5,8,12,15,17-20H2,1H3,(H,23,26)/b9-6-,10-7-,14-11-,16-13+
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]-CP-55,940 from rat forebrain membrane which expresses Cannabinoid receptor 1 in the presence of PMSFMore data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Utrecht University

Curated by ChEMBL
LigandPNGBDBM50117253(15-Hydroxy-icosa-5,8,11,13-tetraenoic acid 2,3-dih...)
Show SMILES CCCCC[C@H](O)\C=C\C=C/C\C=C/C\C=C/CCCC(=O)OC[C@H](O)CO
Show InChI InChI=1S/C23H38O5/c1-2-3-13-16-21(25)17-14-11-9-7-5-4-6-8-10-12-15-18-23(27)28-20-22(26)19-24/h4-5,8-11,14,17,21-22,24-26H,2-3,6-7,12-13,15-16,18-20H2,1H3/b5-4-,10-8-,11-9-,17-14+/t21-,22+/m0/s1
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]-CP-55,940 from rat forebrain membrane which expresses Cannabinoid receptor 2 in the presence of PMSFMore data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Utrecht University

Curated by ChEMBL
LigandPNGBDBM50117244(CHEMBL262560 | Icosa-5,8,11,14-tetraenoic acid 2,3...)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)OC[C@H](O)CO
Show InChI InChI=1S/C23H38O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-23(26)27-21-22(25)20-24/h6-7,9-10,12-13,15-16,22,24-25H,2-5,8,11,14,17-21H2,1H3/b7-6-,10-9-,13-12-,16-15-/t22-/m1/s1
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]-CP-55,940 from rat forebrain membrane which expresses Cannabinoid receptor 1 in the presence of PMSFMore data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Utrecht University

Curated by ChEMBL
LigandPNGBDBM50117243(8,15-Dihydroxy-icosa-5,9,11,13-tetraenoic acid (2-...)
Show SMILES CCCCC[C@H](O)\C=C\C=C/C=C/[C@@H](O)C\C=C/CCCC(=O)NCCO
Show InChI InChI=1S/C22H37NO4/c1-2-3-8-13-20(25)14-9-4-5-10-15-21(26)16-11-6-7-12-17-22(27)23-18-19-24/h4-6,9-11,14-15,20-21,24-26H,2-3,7-8,12-13,16-19H2,1H3,(H,23,27)/b5-4-,11-6-,14-9+,15-10+/t20-,21+/m0/s1
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]-CP-55,940 from rat forebrain membrane which expresses Cannabinoid receptor 2 in the presence of PMSFMore data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Utrecht University

Curated by ChEMBL
LigandPNGBDBM50117252(15-Hydroxy-icosa-5,8,11,13-tetraenoic acid (2-hydr...)
Show SMILES CCCCC[C@@H](O)\C=C\C=C/C\C=C/C\C=C/CCCC(=O)NCCO
Show InChI InChI=1S/C22H37NO3/c1-2-3-13-16-21(25)17-14-11-9-7-5-4-6-8-10-12-15-18-22(26)23-19-20-24/h4-5,8-11,14,17,21,24-25H,2-3,6-7,12-13,15-16,18-20H2,1H3,(H,23,26)/b5-4-,10-8-,11-9-,17-14+/t21-/m1/s1
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]-CP-55,940 from rat forebrain membrane which expresses Cannabinoid receptor 2 in the presence of PMSFMore data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Utrecht University

Curated by ChEMBL
LigandPNGBDBM50117249((2S)-2,3-dihydroxypropyl (5Z,8Z,11Z,14Z)-icosa-5,8...)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)OC[C@@H](O)CO
Show InChI InChI=1S/C23H38O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-23(26)27-21-22(25)20-24/h6-7,9-10,12-13,15-16,22,24-25H,2-5,8,11,14,17-21H2,1H3/b7-6-,10-9-,13-12-,16-15-/t22-/m0/s1
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]-CP-55,940 from rat forebrain membrane which expresses Cannabinoid receptor 1 in the presence of PMSFMore data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Utrecht University

Curated by ChEMBL
LigandPNGBDBM50117248(5-Hydroxy-icosa-6,8,11,14-tetraenoic acid (2-hydro...)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C=C/[C@H](O)CCCC(=O)NCCO
Show InChI InChI=1S/C22H37NO3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-16-21(25)17-15-18-22(26)23-19-20-24/h6-7,9-10,12-14,16,21,24-25H,2-5,8,11,15,17-20H2,1H3,(H,23,26)/b7-6-,10-9-,13-12-,16-14+/t21-/m0/s1
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]-CP-55,940 from rat forebrain membrane which expresses Cannabinoid receptor 1 in the presence of PMSFMore data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Utrecht University

Curated by ChEMBL
LigandPNGBDBM50117253(15-Hydroxy-icosa-5,8,11,13-tetraenoic acid 2,3-dih...)
Show SMILES CCCCC[C@H](O)\C=C\C=C/C\C=C/C\C=C/CCCC(=O)OC[C@H](O)CO
Show InChI InChI=1S/C23H38O5/c1-2-3-13-16-21(25)17-14-11-9-7-5-4-6-8-10-12-15-18-23(27)28-20-22(26)19-24/h4-5,8-11,14,17,21-22,24-26H,2-3,6-7,12-13,15-16,18-20H2,1H3/b5-4-,10-8-,11-9-,17-14+/t21-,22+/m0/s1
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]-CP-55,940 from rat forebrain membrane which expresses Cannabinoid receptor 1 in the presence of PMSFMore data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Utrecht University

Curated by ChEMBL
LigandPNGBDBM50117246(5,15-Dihydroxy-icosa-6,8,11,13-tetraenoic acid (2-...)
Show SMILES CCCCC[C@@H](O)\C=C\C=C/C\C=C/C=C/[C@H](O)CCCC(=O)NCCO
Show InChI InChI=1S/C22H37NO4/c1-2-3-9-13-20(25)14-10-7-5-4-6-8-11-15-21(26)16-12-17-22(27)23-18-19-24/h5-8,10-11,14-15,20-21,24-26H,2-4,9,12-13,16-19H2,1H3,(H,23,27)/b7-5-,8-6-,14-10+,15-11+/t20-,21+/m1/s1
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]-CP-55,940 from rat forebrain membrane which expresses Cannabinoid receptor 1 in the presence of PMSFMore data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Utrecht University

Curated by ChEMBL
LigandPNGBDBM50117254(11-Hydroxy-icosa-5,8,12,14-tetraenoic acid (2-hydr...)
Show SMILES CCCCC\C=C/C=C/C(O)C\C=C/C\C=C/CCCC(=O)NCCO
Show InChI InChI=1S/C22H37NO3/c1-2-3-4-5-7-10-13-16-21(25)17-14-11-8-6-9-12-15-18-22(26)23-19-20-24/h6-7,9-11,13-14,16,21,24-25H,2-5,8,12,15,17-20H2,1H3,(H,23,26)/b9-6-,10-7-,14-11-,16-13+
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]-CP-55,940 from rat forebrain membrane which expresses Cannabinoid receptor 2 in the presence of PMSFMore data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Utrecht University

Curated by ChEMBL
LigandPNGBDBM50117250(15-Hydroxy-icosa-5,8,11,13-tetraenoic acid (2-hydr...)
Show SMILES CCCCCC(O)\C=C\C=C/C\C=C/C\C=C/CCCC(=O)NCCO
Show InChI InChI=1S/C22H37NO3/c1-2-3-13-16-21(25)17-14-11-9-7-5-4-6-8-10-12-15-18-22(26)23-19-20-24/h4-5,8-11,14,17,21,24-25H,2-3,6-7,12-13,15-16,18-20H2,1H3,(H,23,26)/b5-4-,10-8-,11-9-,17-14+
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]-CP-55,940 from rat forebrain membrane which expresses Cannabinoid receptor 2 in the presence of PMSFMore data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Utrecht University

Curated by ChEMBL
LigandPNGBDBM50117256(15-Hydroxy-icosa-5,8,11,13-tetraenoic acid 2,3-dih...)
Show SMILES CCCCC[C@H](O)\C=C\C=C/C\C=C/C\C=C/CCCC(=O)OC[C@@H](O)CO
Show InChI InChI=1S/C23H38O5/c1-2-3-13-16-21(25)17-14-11-9-7-5-4-6-8-10-12-15-18-23(27)28-20-22(26)19-24/h4-5,8-11,14,17,21-22,24-26H,2-3,6-7,12-13,15-16,18-20H2,1H3/b5-4-,10-8-,11-9-,17-14+/t21-,22-/m0/s1
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]-CP-55,940 from rat forebrain membrane which expresses Cannabinoid receptor 1 in the presence of PMSFMore data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Utrecht University

Curated by ChEMBL
LigandPNGBDBM50117247(11-Hydroxy-icosa-5,8,12,14-tetraenoic acid (2-hydr...)
Show SMILES CCCCC\C=C/C=C/[C@@H](O)C\C=C/C\C=C/CCCC(=O)NCCO
Show InChI InChI=1S/C22H37NO3/c1-2-3-4-5-7-10-13-16-21(25)17-14-11-8-6-9-12-15-18-22(26)23-19-20-24/h6-7,9-11,13-14,16,21,24-25H,2-5,8,12,15,17-20H2,1H3,(H,23,26)/b9-6-,10-7-,14-11-,16-13+/t21-/m1/s1
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]-CP-55,940 from rat forebrain membrane which expresses Cannabinoid receptor 2 in the presence of PMSFMore data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Utrecht University

Curated by ChEMBL
LigandPNGBDBM50117244(CHEMBL262560 | Icosa-5,8,11,14-tetraenoic acid 2,3...)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)OC[C@H](O)CO
Show InChI InChI=1S/C23H38O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-23(26)27-21-22(25)20-24/h6-7,9-10,12-13,15-16,22,24-25H,2-5,8,11,14,17-21H2,1H3/b7-6-,10-9-,13-12-,16-15-/t22-/m1/s1
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]-CP-55,940 from rat forebrain membrane which expresses Cannabinoid receptor 2 in the presence of PMSFMore data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Utrecht University

Curated by ChEMBL
LigandPNGBDBM50117249((2S)-2,3-dihydroxypropyl (5Z,8Z,11Z,14Z)-icosa-5,8...)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)OC[C@@H](O)CO
Show InChI InChI=1S/C23H38O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-23(26)27-21-22(25)20-24/h6-7,9-10,12-13,15-16,22,24-25H,2-5,8,11,14,17-21H2,1H3/b7-6-,10-9-,13-12-,16-15-/t22-/m0/s1
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]-CP-55,940 from rat forebrain membrane which expresses Cannabinoid receptor 2 in the presence of PMSFMore data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Utrecht University

Curated by ChEMBL
LigandPNGBDBM50117246(5,15-Dihydroxy-icosa-6,8,11,13-tetraenoic acid (2-...)
Show SMILES CCCCC[C@@H](O)\C=C\C=C/C\C=C/C=C/[C@H](O)CCCC(=O)NCCO
Show InChI InChI=1S/C22H37NO4/c1-2-3-9-13-20(25)14-10-7-5-4-6-8-11-15-21(26)16-12-17-22(27)23-18-19-24/h5-8,10-11,14-15,20-21,24-26H,2-4,9,12-13,16-19H2,1H3,(H,23,27)/b7-5-,8-6-,14-10+,15-11+/t20-,21+/m1/s1
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]-CP-55,940 from rat forebrain membrane which expresses Cannabinoid receptor 2 in the presence of PMSFMore data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Utrecht University

Curated by ChEMBL
LigandPNGBDBM50117243(8,15-Dihydroxy-icosa-5,9,11,13-tetraenoic acid (2-...)
Show SMILES CCCCC[C@H](O)\C=C\C=C/C=C/[C@@H](O)C\C=C/CCCC(=O)NCCO
Show InChI InChI=1S/C22H37NO4/c1-2-3-8-13-20(25)14-9-4-5-10-15-21(26)16-11-6-7-12-17-22(27)23-18-19-24/h4-6,9-11,14-15,20-21,24-26H,2-3,7-8,12-13,16-19H2,1H3,(H,23,27)/b5-4-,11-6-,14-9+,15-10+/t20-,21+/m0/s1
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]-CP-55,940 from rat forebrain membrane which expresses Cannabinoid receptor 1 in the presence of PMSFMore data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Utrecht University

Curated by ChEMBL
LigandPNGBDBM50117251(13-Hydroxy-octadeca-9,11-dienoic acid (2-hydroxy-e...)
Show SMILES CCCCC[C@H](O)\C=C\C=C/CCCCCCCC(=O)NCCO
Show InChI InChI=1S/C20H37NO3/c1-2-3-11-14-19(23)15-12-9-7-5-4-6-8-10-13-16-20(24)21-17-18-22/h7,9,12,15,19,22-23H,2-6,8,10-11,13-14,16-18H2,1H3,(H,21,24)/b9-7-,15-12+/t19-/m0/s1
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]-CP-55,940 from rat forebrain membrane which expresses Cannabinoid receptor 1 in the presence of PMSFMore data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Rattus norvegicus (rat))
Utrecht University

Curated by ChEMBL
LigandPNGBDBM50117247(11-Hydroxy-icosa-5,8,12,14-tetraenoic acid (2-hydr...)
Show SMILES CCCCC\C=C/C=C/[C@@H](O)C\C=C/C\C=C/CCCC(=O)NCCO
Show InChI InChI=1S/C22H37NO3/c1-2-3-4-5-7-10-13-16-21(25)17-14-11-8-6-9-12-15-18-22(26)23-19-20-24/h6-7,9-11,13-14,16,21,24-25H,2-5,8,12,15,17-20H2,1H3,(H,23,26)/b9-6-,10-7-,14-11-,16-13+/t21-/m1/s1
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]-CP-55,940 from rat forebrain membrane which expresses Cannabinoid receptor 1 in the presence of PMSFMore data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Rattus norvegicus (Rat))
Utrecht University

Curated by ChEMBL
LigandPNGBDBM50117248(5-Hydroxy-icosa-6,8,11,14-tetraenoic acid (2-hydro...)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C=C/[C@H](O)CCCC(=O)NCCO
Show InChI InChI=1S/C22H37NO3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-16-21(25)17-15-18-22(26)23-19-20-24/h6-7,9-10,12-14,16,21,24-25H,2-5,8,11,15,17-20H2,1H3,(H,23,26)/b7-6-,10-9-,13-12-,16-14+/t21-/m0/s1
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]-CP-55,940 from rat forebrain membrane which expresses Cannabinoid receptor 2 in the presence of PMSFMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Utrecht University

Curated by ChEMBL
LigandPNGBDBM50117246(5,15-Dihydroxy-icosa-6,8,11,13-tetraenoic acid (2-...)
Show SMILES CCCCC[C@@H](O)\C=C\C=C/C\C=C/C=C/[C@H](O)CCCC(=O)NCCO
Show InChI InChI=1S/C22H37NO4/c1-2-3-9-13-20(25)14-10-7-5-4-6-8-11-15-21(26)16-12-17-22(27)23-18-19-24/h5-8,10-11,14-15,20-21,24-26H,2-4,9,12-13,16-19H2,1H3,(H,23,27)/b7-5-,8-6-,14-10+,15-11+/t20-,21+/m1/s1
Affinity DataKi:  1.26E+3nMAssay Description:Inhibition of Fatty-acid amide hydrolase (FAAH) activity in human lymphoma U937 cell using [3H]-AEA as substrate in the 0-25 uM concMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Utrecht University

Curated by ChEMBL
LigandPNGBDBM50117255(5-Hydroxy-icosa-6,8,11,14-tetraenoic acid (2-hydro...)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C=C/[C@@H](O)CCCC(=O)NCCO
Show InChI InChI=1S/C22H37NO3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-16-21(25)17-15-18-22(26)23-19-20-24/h6-7,9-10,12-14,16,21,24-25H,2-5,8,11,15,17-20H2,1H3,(H,23,26)/b7-6-,10-9-,13-12-,16-14+/t21-/m1/s1
Affinity DataKi:  1.89E+3nMAssay Description:Inhibition of Fatty-acid amide hydrolase (FAAH) activity in human lymphoma U937 cell using [3H]-AEA as substrate in the 0-25 uM concMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Utrecht University

Curated by ChEMBL
LigandPNGBDBM50117244(CHEMBL262560 | Icosa-5,8,11,14-tetraenoic acid 2,3...)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)OC[C@H](O)CO
Show InChI InChI=1S/C23H38O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-23(26)27-21-22(25)20-24/h6-7,9-10,12-13,15-16,22,24-25H,2-5,8,11,14,17-21H2,1H3/b7-6-,10-9-,13-12-,16-15-/t22-/m1/s1
Affinity DataKi:  2.50E+3nMAssay Description:Inhibition of Fatty-acid amide hydrolase (FAAH) activity in human lymphoma U937 cell using [3H]-AEA as substrate in the 0-25 uM concMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Utrecht University

Curated by ChEMBL
LigandPNGBDBM50117248(5-Hydroxy-icosa-6,8,11,14-tetraenoic acid (2-hydro...)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C=C/[C@H](O)CCCC(=O)NCCO
Show InChI InChI=1S/C22H37NO3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-16-21(25)17-15-18-22(26)23-19-20-24/h6-7,9-10,12-14,16,21,24-25H,2-5,8,11,15,17-20H2,1H3,(H,23,26)/b7-6-,10-9-,13-12-,16-14+/t21-/m0/s1
Affinity DataKi:  2.52E+3nMAssay Description:Inhibition of Fatty-acid amide hydrolase (FAAH) activity in human lymphoma U937 cell using [3H]-AEA as substrate in the 0-25 uM concMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Utrecht University

Curated by ChEMBL
LigandPNGBDBM50117245(12-Hydroxy-icosa-5,8,10,14-tetraenoic acid (2-hydr...)
Show SMILES CCCCC\C=C/C[C@@H](O)\C=C\C=C/C\C=C/CCCC(=O)NCCO
Show InChI InChI=1S/C22H37NO3/c1-2-3-4-5-10-13-16-21(25)17-14-11-8-6-7-9-12-15-18-22(26)23-19-20-24/h7-11,13-14,17,21,24-25H,2-6,12,15-16,18-20H2,1H3,(H,23,26)/b9-7-,11-8-,13-10-,17-14+/t21-/m1/s1
Affinity DataKi:  2.90E+3nMAssay Description:Inhibition of Fatty-acid amide hydrolase (FAAH) activity in human lymphoma U937 cell using [3H]-AEA as substrate in the 0-25 uM concMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Utrecht University

Curated by ChEMBL
LigandPNGBDBM50117249((2S)-2,3-dihydroxypropyl (5Z,8Z,11Z,14Z)-icosa-5,8...)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)OC[C@@H](O)CO
Show InChI InChI=1S/C23H38O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-23(26)27-21-22(25)20-24/h6-7,9-10,12-13,15-16,22,24-25H,2-5,8,11,14,17-21H2,1H3/b7-6-,10-9-,13-12-,16-15-/t22-/m0/s1
Affinity DataKi:  3.00E+3nMAssay Description:Inhibition of Fatty-acid amide hydrolase (FAAH) activity in human lymphoma U937 cell using [3H]-AEA as substrate in the 0-25 uM concMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Utrecht University

Curated by ChEMBL
LigandPNGBDBM50117253(15-Hydroxy-icosa-5,8,11,13-tetraenoic acid 2,3-dih...)
Show SMILES CCCCC[C@H](O)\C=C\C=C/C\C=C/C\C=C/CCCC(=O)OC[C@H](O)CO
Show InChI InChI=1S/C23H38O5/c1-2-3-13-16-21(25)17-14-11-9-7-5-4-6-8-10-12-15-18-23(27)28-20-22(26)19-24/h4-5,8-11,14,17,21-22,24-26H,2-3,6-7,12-13,15-16,18-20H2,1H3/b5-4-,10-8-,11-9-,17-14+/t21-,22+/m0/s1
Affinity DataKi:  5.00E+3nMAssay Description:Inhibition of Fatty-acid amide hydrolase (FAAH) activity in human lymphoma U937 cell using [3H]-AEA as substrate in the 0-25 uM concMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Utrecht University

Curated by ChEMBL
LigandPNGBDBM26144(1,3-dihydroxypropan-2-yl (5Z,8Z,11Z,14Z)-icosa-5,8...)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)OC(CO)CO
Show InChI InChI=1S/C23H38O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-23(26)27-22(20-24)21-25/h6-7,9-10,12-13,15-16,22,24-25H,2-5,8,11,14,17-21H2,1H3/b7-6-,10-9-,13-12-,16-15-
Affinity DataKi:  5.00E+3nMAssay Description:Inhibition of Fatty-acid amide hydrolase (FAAH) activity in human lymphoma U937 cell using [3H]-AEA as substrate in the 0-25 uM concMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Utrecht University

Curated by ChEMBL
LigandPNGBDBM50117256(15-Hydroxy-icosa-5,8,11,13-tetraenoic acid 2,3-dih...)
Show SMILES CCCCC[C@H](O)\C=C\C=C/C\C=C/C\C=C/CCCC(=O)OC[C@@H](O)CO
Show InChI InChI=1S/C23H38O5/c1-2-3-13-16-21(25)17-14-11-9-7-5-4-6-8-10-12-15-18-23(27)28-20-22(26)19-24/h4-5,8-11,14,17,21-22,24-26H,2-3,6-7,12-13,15-16,18-20H2,1H3/b5-4-,10-8-,11-9-,17-14+/t21-,22-/m0/s1
Affinity DataKi:  6.00E+3nMAssay Description:Inhibition of Fatty-acid amide hydrolase (FAAH) activity in human lymphoma U937 cell using [3H]-AEA as substrate in the 0-25 uM concMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Utrecht University

Curated by ChEMBL
LigandPNGBDBM22988((5Z,8Z,11Z,14Z)-N-(2-hydroxyethyl)icosa-5,8,11,14-...)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)NCCO
Show InChI InChI=1S/C22H37NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-22(25)23-20-21-24/h6-7,9-10,12-13,15-16,24H,2-5,8,11,14,17-21H2,1H3,(H,23,25)/b7-6-,10-9-,13-12-,16-15-
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of Fatty-acid amide hydrolase (FAAH) activity in human lymphoma U937 cell using [3H]-AEA as substrate in the 0-25 uM concMore data for this Ligand-Target Pair