Compile Data Set for Download or QSAR
maximum 50k data
Found 48 Enz. Inhib. hit(s) with all data for entry = 7388
TargetCannabinoid receptor 1(Homo sapiens (Human))
Research Triangle Institute

US Patent
LigandPNGBDBM192521(US9187480, 4-[8-(2-chlorophenyl)-9-(4-chlorophenyl...)
Affinity DataKi:  0.280nMAssay Description:Further characterization of select compounds was performed using radioligand displacement of [3H]1 and equilibrium dissociation constant (Ki) values ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Research Triangle Institute

US Patent
LigandPNGBDBM192536(US9187480, N-{1-[8-(2-chlorophenyl)-9-(4-chlorophe...)
Affinity DataKi:  1.54nMAssay Description:Further characterization of select compounds was performed using radioligand displacement of [3H]1 and equilibrium dissociation constant (Ki) values ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Research Triangle Institute

US Patent
LigandPNGBDBM192521(US9187480, 4-[8-(2-chlorophenyl)-9-(4-chlorophenyl...)
Affinity DataKi:  1.79nMAssay Description:Further characterization of select compounds was performed using radioligand displacement of [3H]1 and equilibrium dissociation constant (Ki) values ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Research Triangle Institute

US Patent
LigandPNGBDBM192534(US9187480, N-{1-[8-(2-chlorophenyl)-9-(4-chlorophe...)
Affinity DataKi:  1.93nMAssay Description:Further characterization of select compounds was performed using radioligand displacement of [3H]1 and equilibrium dissociation constant (Ki) values ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Research Triangle Institute

US Patent
LigandPNGBDBM192538(US9187480, N-{1-[8-(2-chlorophenyl)-9-(4-chlorophe...)
Affinity DataKi:  2.02nMAssay Description:Further characterization of select compounds was performed using radioligand displacement of [3H]1 and equilibrium dissociation constant (Ki) values ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Research Triangle Institute

US Patent
LigandPNGBDBM192530(US9187480, N-{1-[8-(2-chlorophenyl)-9-(4-chlorophe...)
Affinity DataKi:  2.55nMAssay Description:Further characterization of select compounds was performed using radioligand displacement of [3H]1 and equilibrium dissociation constant (Ki) values ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Research Triangle Institute

US Patent
LigandPNGBDBM192537(US9187480, N-{1-[8-(2-chlorophenyl)-9-(4-chlorophe...)
Affinity DataKi:  2.67nMAssay Description:Further characterization of select compounds was performed using radioligand displacement of [3H]1 and equilibrium dissociation constant (Ki) values ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Research Triangle Institute

US Patent
LigandPNGBDBM192532(US9187480, N-{1-[8-(2-chlorophenyl)-9-(4-chlorophe...)
Affinity DataKi:  3.35nMAssay Description:Further characterization of select compounds was performed using radioligand displacement of [3H]1 and equilibrium dissociation constant (Ki) values ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Research Triangle Institute

US Patent
LigandPNGBDBM192529(US9187480, ethyl N-{1-[8-(2-chlorophenyl)-9-(4-chl...)
Affinity DataKi:  3.57nMAssay Description:Further characterization of select compounds was performed using radioligand displacement of [3H]1 and equilibrium dissociation constant (Ki) values ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Research Triangle Institute

US Patent
LigandPNGBDBM192535(US9187480, N-{1-[8-(2-chlorophenyl)-9-(4-chlorophe...)
Affinity DataKi:  4.01nMAssay Description:Further characterization of select compounds was performed using radioligand displacement of [3H]1 and equilibrium dissociation constant (Ki) values ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Research Triangle Institute

US Patent
LigandPNGBDBM192528(US9187480, N-tert-butyl-1-[8-(2-chlorophenyl)-9-(4...)
Affinity DataKi:  4.08nMAssay Description:Further characterization of select compounds was performed using radioligand displacement of [3H]1 and equilibrium dissociation constant (Ki) values ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Research Triangle Institute

US Patent
LigandPNGBDBM192527(US9187480, N-{1-[8-(2-chlorophenyl)-9-(4-chlorophe...)
Affinity DataKi:  6nMAssay Description:Further characterization of select compounds was performed using radioligand displacement of [3H]1 and equilibrium dissociation constant (Ki) values ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Research Triangle Institute

US Patent
LigandPNGBDBM192531(US9187480, 8-(2-chlorophenyl)-9-(4-chlorophenyl)-6...)
Affinity DataKi:  6.10nMAssay Description:Further characterization of select compounds was performed using radioligand displacement of [3H]1 and equilibrium dissociation constant (Ki) values ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Research Triangle Institute

US Patent
LigandPNGBDBM192526(US9187480, N-{4-[8-(2-chlorophenyl)-9-(4-chlorophe...)
Affinity DataKi:  6.21nMAssay Description:Further characterization of select compounds was performed using radioligand displacement of [3H]1 and equilibrium dissociation constant (Ki) values ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Research Triangle Institute

US Patent
LigandPNGBDBM50399533(CHEMBL2180216 | US9187480, tert-butyl N-{1-[8-(2-c...)
Affinity DataKi:  7.12nMAssay Description:Further characterization of select compounds was performed using radioligand displacement of [3H]1 and equilibrium dissociation constant (Ki) values ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Research Triangle Institute

US Patent
LigandPNGBDBM192525(US9187480, 4-[8-(2-chlorophenyl)-9-(4-chlorophenyl...)
Affinity DataKi:  11nMAssay Description:Further characterization of select compounds was performed using radioligand displacement of [3H]1 and equilibrium dissociation constant (Ki) values ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Research Triangle Institute

US Patent
LigandPNGBDBM192524(US9187480, 4-[8-(2-chlorophenyl)-9-(4-chlorophenyl...)
Affinity DataKi:  16.8nMAssay Description:Further characterization of select compounds was performed using radioligand displacement of [3H]1 and equilibrium dissociation constant (Ki) values ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Research Triangle Institute

US Patent
LigandPNGBDBM192533(US9187480, N-{1-[8-(2-chlorophenyl)-9-(4-chlorophe...)
Affinity DataKi:  19.5nMAssay Description:Further characterization of select compounds was performed using radioligand displacement of [3H]1 and equilibrium dissociation constant (Ki) values ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Research Triangle Institute

US Patent
LigandPNGBDBM50399525(CHEMBL2180226 | US9187480, tert-butyl 4-{[8-(2-chl...)
Affinity DataKi:  23.9nMAssay Description:Further characterization of select compounds was performed using radioligand displacement of [3H]1 and equilibrium dissociation constant (Ki) values ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Research Triangle Institute

US Patent
LigandPNGBDBM50399530(CHEMBL2180219 | US9187480, 3-tert-butyl-1-{1-[8-(2...)
Affinity DataKi:  25.5nMAssay Description:Further characterization of select compounds was performed using radioligand displacement of [3H]1 and equilibrium dissociation constant (Ki) values ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Research Triangle Institute

US Patent
LigandPNGBDBM192524(US9187480, 4-[8-(2-chlorophenyl)-9-(4-chlorophenyl...)
Affinity DataKi:  32.1nMAssay Description:Further characterization of select compounds was performed using radioligand displacement of [3H]1 and equilibrium dissociation constant (Ki) values ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Research Triangle Institute

US Patent
LigandPNGBDBM192522(US9187480, N-{[4-({[8-(2-chlorophenyl)-9-(4-chloro...)
Affinity DataKi:  44.5nMAssay Description:Further characterization of select compounds was performed using radioligand displacement of [3H]1 and equilibrium dissociation constant (Ki) values ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Research Triangle Institute

US Patent
LigandPNGBDBM192536(US9187480, N-{1-[8-(2-chlorophenyl)-9-(4-chlorophe...)
Affinity DataKi:  60.2nMAssay Description:Further characterization of select compounds was performed using radioligand displacement of [3H]1 and equilibrium dissociation constant (Ki) values ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Research Triangle Institute

US Patent
LigandPNGBDBM192535(US9187480, N-{1-[8-(2-chlorophenyl)-9-(4-chlorophe...)
Affinity DataKi:  89.5nMAssay Description:Further characterization of select compounds was performed using radioligand displacement of [3H]1 and equilibrium dissociation constant (Ki) values ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Research Triangle Institute

US Patent
LigandPNGBDBM192523(US9187480, N-{[4-({[8-(2-chlorophenyl)-9-(4-chloro...)
Affinity DataKi:  94.5nMAssay Description:Further characterization of select compounds was performed using radioligand displacement of [3H]1 and equilibrium dissociation constant (Ki) values ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Research Triangle Institute

US Patent
LigandPNGBDBM50399529(CHEMBL2180220 | US9187480, 1-{1-[8-(2-chlorophenyl...)
Affinity DataKi:  195nMAssay Description:Further characterization of select compounds was performed using radioligand displacement of [3H]1 and equilibrium dissociation constant (Ki) values ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Research Triangle Institute

US Patent
LigandPNGBDBM192537(US9187480, N-{1-[8-(2-chlorophenyl)-9-(4-chlorophe...)
Affinity DataKi:  215nMAssay Description:Further characterization of select compounds was performed using radioligand displacement of [3H]1 and equilibrium dissociation constant (Ki) values ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Research Triangle Institute

US Patent
LigandPNGBDBM192522(US9187480, N-{[4-({[8-(2-chlorophenyl)-9-(4-chloro...)
Affinity DataKi:  258nMAssay Description:Further characterization of select compounds was performed using radioligand displacement of [3H]1 and equilibrium dissociation constant (Ki) values ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Research Triangle Institute

US Patent
LigandPNGBDBM192523(US9187480, N-{[4-({[8-(2-chlorophenyl)-9-(4-chloro...)
Affinity DataKi:  355nMAssay Description:Further characterization of select compounds was performed using radioligand displacement of [3H]1 and equilibrium dissociation constant (Ki) values ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Research Triangle Institute

US Patent
LigandPNGBDBM192529(US9187480, ethyl N-{1-[8-(2-chlorophenyl)-9-(4-chl...)
Affinity DataKi:  426nMAssay Description:Further characterization of select compounds was performed using radioligand displacement of [3H]1 and equilibrium dissociation constant (Ki) values ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Research Triangle Institute

US Patent
LigandPNGBDBM192538(US9187480, N-{1-[8-(2-chlorophenyl)-9-(4-chlorophe...)
Affinity DataKi:  569nMAssay Description:Further characterization of select compounds was performed using radioligand displacement of [3H]1 and equilibrium dissociation constant (Ki) values ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Research Triangle Institute

US Patent
LigandPNGBDBM192527(US9187480, N-{1-[8-(2-chlorophenyl)-9-(4-chlorophe...)
Affinity DataKi:  726nMAssay Description:Further characterization of select compounds was performed using radioligand displacement of [3H]1 and equilibrium dissociation constant (Ki) values ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Research Triangle Institute

US Patent
LigandPNGBDBM192524(US9187480, 4-[8-(2-chlorophenyl)-9-(4-chlorophenyl...)
Affinity DataKi:  834nMAssay Description:Further characterization of select compounds was performed using radioligand displacement of [3H]1 and equilibrium dissociation constant (Ki) values ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Research Triangle Institute

US Patent
LigandPNGBDBM192532(US9187480, N-{1-[8-(2-chlorophenyl)-9-(4-chlorophe...)
Affinity DataKi:  835nMAssay Description:Further characterization of select compounds was performed using radioligand displacement of [3H]1 and equilibrium dissociation constant (Ki) values ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Research Triangle Institute

US Patent
LigandPNGBDBM192526(US9187480, N-{4-[8-(2-chlorophenyl)-9-(4-chlorophe...)
Affinity DataKi:  948nMAssay Description:Further characterization of select compounds was performed using radioligand displacement of [3H]1 and equilibrium dissociation constant (Ki) values ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Research Triangle Institute

US Patent
LigandPNGBDBM192533(US9187480, N-{1-[8-(2-chlorophenyl)-9-(4-chlorophe...)
Affinity DataKi:  1.05E+3nMAssay Description:Further characterization of select compounds was performed using radioligand displacement of [3H]1 and equilibrium dissociation constant (Ki) values ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Research Triangle Institute

US Patent
LigandPNGBDBM192525(US9187480, 4-[8-(2-chlorophenyl)-9-(4-chlorophenyl...)
Affinity DataKi:  1.66E+3nMAssay Description:Further characterization of select compounds was performed using radioligand displacement of [3H]1 and equilibrium dissociation constant (Ki) values ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Research Triangle Institute

US Patent
LigandPNGBDBM192522(US9187480, N-{[4-({[8-(2-chlorophenyl)-9-(4-chloro...)
Affinity DataKi:  2.23E+3nMAssay Description:Further characterization of select compounds was performed using radioligand displacement of [3H]1 and equilibrium dissociation constant (Ki) values ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Research Triangle Institute

US Patent
LigandPNGBDBM192534(US9187480, N-{1-[8-(2-chlorophenyl)-9-(4-chlorophe...)
Affinity DataKi:  2.36E+3nMAssay Description:Further characterization of select compounds was performed using radioligand displacement of [3H]1 and equilibrium dissociation constant (Ki) values ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Research Triangle Institute

US Patent
LigandPNGBDBM192531(US9187480, 8-(2-chlorophenyl)-9-(4-chlorophenyl)-6...)
Affinity DataKi:  4.50E+3nMAssay Description:Further characterization of select compounds was performed using radioligand displacement of [3H]1 and equilibrium dissociation constant (Ki) values ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Research Triangle Institute

US Patent
LigandPNGBDBM50399529(CHEMBL2180220 | US9187480, 1-{1-[8-(2-chlorophenyl...)
Affinity DataKi:  4.65E+3nMAssay Description:Further characterization of select compounds was performed using radioligand displacement of [3H]1 and equilibrium dissociation constant (Ki) values ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Research Triangle Institute

US Patent
LigandPNGBDBM192521(US9187480, 4-[8-(2-chlorophenyl)-9-(4-chlorophenyl...)
Affinity DataKi:  5.51E+3nMAssay Description:Further characterization of select compounds was performed using radioligand displacement of [3H]1 and equilibrium dissociation constant (Ki) values ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Research Triangle Institute

US Patent
LigandPNGBDBM192530(US9187480, N-{1-[8-(2-chlorophenyl)-9-(4-chlorophe...)
Affinity DataKi:  1.06E+4nMAssay Description:Further characterization of select compounds was performed using radioligand displacement of [3H]1 and equilibrium dissociation constant (Ki) values ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Research Triangle Institute

US Patent
LigandPNGBDBM192523(US9187480, N-{[4-({[8-(2-chlorophenyl)-9-(4-chloro...)
Affinity DataKi:  1.07E+4nMAssay Description:Further characterization of select compounds was performed using radioligand displacement of [3H]1 and equilibrium dissociation constant (Ki) values ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Research Triangle Institute

US Patent
LigandPNGBDBM50399525(CHEMBL2180226 | US9187480, tert-butyl 4-{[8-(2-chl...)
Affinity DataKi:  1.36E+4nMAssay Description:Further characterization of select compounds was performed using radioligand displacement of [3H]1 and equilibrium dissociation constant (Ki) values ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Research Triangle Institute

US Patent
LigandPNGBDBM50399533(CHEMBL2180216 | US9187480, tert-butyl N-{1-[8-(2-c...)
Affinity DataKi:  1.39E+4nMAssay Description:Further characterization of select compounds was performed using radioligand displacement of [3H]1 and equilibrium dissociation constant (Ki) values ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Research Triangle Institute

US Patent
LigandPNGBDBM192528(US9187480, N-tert-butyl-1-[8-(2-chlorophenyl)-9-(4...)
Affinity DataKi:  2.00E+4nMAssay Description:Further characterization of select compounds was performed using radioligand displacement of [3H]1 and equilibrium dissociation constant (Ki) values ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Research Triangle Institute

US Patent
LigandPNGBDBM50399530(CHEMBL2180219 | US9187480, 3-tert-butyl-1-{1-[8-(2...)
Affinity DataKi:  2.00E+4nMAssay Description:Further characterization of select compounds was performed using radioligand displacement of [3H]1 and equilibrium dissociation constant (Ki) values ...More data for this Ligand-Target Pair
In DepthDetails US Patent