BDBM50399525 CHEMBL2180226::US9187480, tert-butyl 4-{[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]amino}piperidine-1-carboxylate

SMILES CC(C)(C)OC(=O)N1CCC(CC1)Nc1ncnc2n(c(nc12)-c1ccccc1Cl)-c1ccc(Cl)cc1

InChI Key InChIKey=NSNQHMACSLZVFE-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50399525   

TargetCannabinoid receptor 1(Homo sapiens (Human))
Research Triangle Institute

US Patent
LigandPNGBDBM50399525(CHEMBL2180226 | US9187480, tert-butyl 4-{[8-(2-chl...)
Affinity DataKi:  23.9nMAssay Description:Further characterization of select compounds was performed using radioligand displacement of [3H]1 and equilibrium dissociation constant (Ki) values ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Research Triangle Institute

US Patent
LigandPNGBDBM50399525(CHEMBL2180226 | US9187480, tert-butyl 4-{[8-(2-chl...)
Affinity DataKi:  24nMAssay Description:Displacement of [3H]CP55940 from human CB1 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Research Triangle Institute

US Patent
LigandPNGBDBM50399525(CHEMBL2180226 | US9187480, tert-butyl 4-{[8-(2-chl...)
Affinity DataKi:  1.36E+4nMAssay Description:Further characterization of select compounds was performed using radioligand displacement of [3H]1 and equilibrium dissociation constant (Ki) values ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
Research Triangle Institute

US Patent
LigandPNGBDBM50399525(CHEMBL2180226 | US9187480, tert-butyl 4-{[8-(2-chl...)
Affinity DataKi:  1.40E+4nMAssay Description:Displacement of [3H]CP55940 from human CB2 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed