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Found 13 Enz. Inhib. hit(s) with all data for entry = 379
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Bayer Intellectual Property

US Patent
LigandPNGBDBM125050(US8772511, 11 | US9714242, 11)
Affinity DataKi:  0.400nMpH: 7.4Assay Description:The [3H]-methyllycaconitine binding assay is a modification of the method described by Davies et al. in Neuropharmacol, 1999, 38, 679-690.Rat brain t...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Bayer Intellectual Property

US Patent
LigandPNGBDBM125047(US8772511, 4 | US9714242, 22)
Affinity DataKi: <1nMpH: 7.4Assay Description:The [3H]-methyllycaconitine binding assay is a modification of the method described by Davies et al. in Neuropharmacol, 1999, 38, 679-690.Rat brain t...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Bayer Intellectual Property

US Patent
LigandPNGBDBM125047(US8772511, 4 | US9714242, 22)
Affinity DataKi:  2.10nMpH: 7.4Assay Description:The [3H]-methyllycaconitine binding assay is a modification of the method described by Davies et al. in Neuropharmacol, 1999, 38, 679-690.Rat brain t...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Bayer Intellectual Property

US Patent
LigandPNGBDBM125051(US8772511, 16 | US9714242, 16)
Affinity DataKi:  4.30nMpH: 7.4Assay Description:The [3H]-methyllycaconitine binding assay is a modification of the method described by Davies et al. in Neuropharmacol, 1999, 38, 679-690.Rat brain t...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Bayer Intellectual Property

US Patent
LigandPNGBDBM125049(US8772511, 6 | US9714242, 6)
Affinity DataKi:  7.90nMpH: 7.4Assay Description:The [3H]-methyllycaconitine binding assay is a modification of the method described by Davies et al. in Neuropharmacol, 1999, 38, 679-690.Rat brain t...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Bayer Intellectual Property

US Patent
LigandPNGBDBM125052(US8772511, 21 | US9714242, 21)
Affinity DataKi:  15nMpH: 7.4Assay Description:The [3H]-methyllycaconitine binding assay is a modification of the method described by Davies et al. in Neuropharmacol, 1999, 38, 679-690.Rat brain t...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Bayer Intellectual Property

US Patent
LigandPNGBDBM125048(US8772511, 5 | US9714242, 5)
Affinity DataKi:  22nMpH: 7.4Assay Description:The [3H]-methyllycaconitine binding assay is a modification of the method described by Davies et al. in Neuropharmacol, 1999, 38, 679-690.Rat brain t...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM125052(US8772511, 21 | US9714242, 21)
Affinity DataKi:  1.60E+3nMpH: 7.4Assay Description:Membranes from HEK293 cells which express recombinant human 5-HT3 receptor (RB-HS3, Receptor Biology, Inc., MD, USA) are diluted in accordance with t...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM125049(US8772511, 6 | US9714242, 6)
Affinity DataKi:  1.70E+3nMpH: 7.4Assay Description:Membranes from HEK293 cells which express recombinant human 5-HT3 receptor (RB-HS3, Receptor Biology, Inc., MD, USA) are diluted in accordance with t...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM125051(US8772511, 16 | US9714242, 16)
Affinity DataKi:  2.10E+3nMpH: 7.4Assay Description:Membranes from HEK293 cells which express recombinant human 5-HT3 receptor (RB-HS3, Receptor Biology, Inc., MD, USA) are diluted in accordance with t...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM125050(US8772511, 11 | US9714242, 11)
Affinity DataKi:  5.50E+3nMpH: 7.4Assay Description:Membranes from HEK293 cells which express recombinant human 5-HT3 receptor (RB-HS3, Receptor Biology, Inc., MD, USA) are diluted in accordance with t...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM264253(N-[(3R)-1-Azabicyclo[2.2.2]oct-3-yl]-6-({[(3,4,5-t...)
Affinity DataKi:  6.90E+3nMpH: 7.4Assay Description:Membranes from HEK293 cells which express recombinant human 5-HT3 receptor (RB-HS3, Receptor Biology, Inc., MD, USA) are diluted in accordance with t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM125048(US8772511, 5 | US9714242, 5)
Affinity DataKi:  1.20E+4nMpH: 7.4Assay Description:Membranes from HEK293 cells which express recombinant human 5-HT3 receptor (RB-HS3, Receptor Biology, Inc., MD, USA) are diluted in accordance with t...More data for this Ligand-Target Pair
In DepthDetails US Patent