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Found 69 Enz. Inhib. hit(s) with all data for entry = 50012856
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123431(7-{7-[1-(1-Imino-ethyl)-piperidin-4-yloxy]-3-oxo-2...)
Affinity DataKi:  0.780nMAssay Description:Binding affinity of the compound towards factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123417(2-[({4-[1-(1-Imino-ethyl)-piperidin-4-yloxy]-pheny...)
Affinity DataIC50:  0.800nMAssay Description:Inhibitory concentration of the compound to factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123412(1-Ethyl-2-{7-[1-(1-imino-ethyl)-piperidin-4-yloxy]...)
Affinity DataIC50:  2nMAssay Description:Inhibitory concentration of the compound to factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123426(2-{7-[1-(1-Imino-ethyl)-piperidin-4-yloxy]-3-oxo-2...)
Affinity DataIC50:  2nMAssay Description:Inhibitory concentration of the compound to factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50084617(((7-carbamimidoyl-naphthalen-2-ylmethyl)-{4-[1-(1-...)
Affinity DataIC50:  2nMAssay Description:Inhibitory concentration of the compound to factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123414(((5-Carbamimidoyl-benzo[b]thiophen-2-ylmethyl)-{4-...)
Affinity DataIC50:  3nMAssay Description:Inhibitory concentration of the compound to factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123429(((3'-Carbamimidoyl-biphenyl-3-ylmethyl)-{4-[1-(1-i...)
Affinity DataIC50:  3nMAssay Description:Inhibitory concentration of the compound to factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123427(3'-{7-[1-(1-Imino-ethyl)-piperidin-4-yloxy]-3-oxo-...)
Affinity DataIC50:  4nMAssay Description:Inhibitory concentration of the compound to factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123422(((7-Carbamimidoyl-naphthalen-2-ylmethyl)-{4-[1-(1-...)
Affinity DataIC50:  6nMAssay Description:Inhibitory concentration of the compound to factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123420(7-[({4-[1-(1-Imino-ethyl)-piperidin-4-yloxy]-pheny...)
Affinity DataIC50:  6nMAssay Description:Inhibitory concentration of the compound to factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123407(2-[({4-[1-(1-Imino-ethyl)-piperidin-4-yloxy]-pheny...)
Affinity DataIC50:  6nMAssay Description:Inhibitory concentration of the compound to factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123431(7-{7-[1-(1-Imino-ethyl)-piperidin-4-yloxy]-3-oxo-2...)
Affinity DataIC50:  6nMAssay Description:Inhibitory concentration of the compound to factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123425(((3'-Carbamimidoyl-biphenyl-3-ylmethyl)-{4-[1-(1-i...)
Affinity DataIC50:  7nMAssay Description:Inhibitory concentration of the compound to factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123415(3'-[({4-[1-(1-Imino-ethyl)-piperidin-4-yloxy]-phen...)
Affinity DataIC50:  7nMAssay Description:Inhibitory concentration of the compound to factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123416(((5-Carbamimidoyl-benzo[b]thiophen-2-ylmethyl)-{4-...)
Affinity DataIC50:  9nMAssay Description:Inhibitory concentration of the compound to factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123421(3-{5-[({4-[1-(1-Imino-ethyl)-piperidin-4-yloxy]-ph...)
Affinity DataIC50:  14nMAssay Description:Inhibitory concentration of the compound to factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAnionic trypsin-2(Rattus norvegicus)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123407(2-[({4-[1-(1-Imino-ethyl)-piperidin-4-yloxy]-pheny...)
Affinity DataIC50:  21nMAssay Description:Inhibitory concentration of the compound against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123408(4'-[({4-[1-(1-Imino-ethyl)-piperidin-4-yloxy]-phen...)
Affinity DataIC50:  25nMAssay Description:Inhibitory concentration of the compound to factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAnionic trypsin-2(Rattus norvegicus)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123417(2-[({4-[1-(1-Imino-ethyl)-piperidin-4-yloxy]-pheny...)
Affinity DataIC50:  25nMAssay Description:Inhibitory concentration of the compound against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAnionic trypsin-2(Rattus norvegicus)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123431(7-{7-[1-(1-Imino-ethyl)-piperidin-4-yloxy]-3-oxo-2...)
Affinity DataIC50:  28nMAssay Description:Inhibitory concentration of the compound against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123413(2-[({4-[1-(1-Imino-ethyl)-piperidin-4-yloxy]-pheny...)
Affinity DataIC50:  31nMAssay Description:Inhibitory concentration of the compound to factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123419(3-(5-{7-[1-(1-Imino-ethyl)-piperidin-4-yloxy]-3-ox...)
Affinity DataIC50:  52nMAssay Description:Inhibitory concentration of the compound to factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAnionic trypsin-2(Rattus norvegicus)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123412(1-Ethyl-2-{7-[1-(1-imino-ethyl)-piperidin-4-yloxy]...)
Affinity DataIC50:  58nMAssay Description:Inhibitory concentration of the compound against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAnionic trypsin-2(Rattus norvegicus)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123414(((5-Carbamimidoyl-benzo[b]thiophen-2-ylmethyl)-{4-...)
Affinity DataIC50:  63nMAssay Description:Inhibitory concentration of the compound against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAnionic trypsin-2(Rattus norvegicus)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50084617(((7-carbamimidoyl-naphthalen-2-ylmethyl)-{4-[1-(1-...)
Affinity DataIC50:  63nMAssay Description:Inhibitory concentration of the compound against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAnionic trypsin-2(Rattus norvegicus)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123426(2-{7-[1-(1-Imino-ethyl)-piperidin-4-yloxy]-3-oxo-2...)
Affinity DataIC50:  76nMAssay Description:Inhibitory concentration of the compound against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAnionic trypsin-2(Rattus norvegicus)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123422(((7-Carbamimidoyl-naphthalen-2-ylmethyl)-{4-[1-(1-...)
Affinity DataIC50:  83nMAssay Description:Inhibitory concentration of the compound against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAnionic trypsin-2(Rattus norvegicus)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123416(((5-Carbamimidoyl-benzo[b]thiophen-2-ylmethyl)-{4-...)
Affinity DataIC50:  86nMAssay Description:Inhibitory concentration of the compound against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAnionic trypsin-2(Rattus norvegicus)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123420(7-[({4-[1-(1-Imino-ethyl)-piperidin-4-yloxy]-pheny...)
Affinity DataIC50:  94nMAssay Description:Inhibitory concentration of the compound against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAnionic trypsin-2(Rattus norvegicus)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123427(3'-{7-[1-(1-Imino-ethyl)-piperidin-4-yloxy]-3-oxo-...)
Affinity DataIC50:  143nMAssay Description:Inhibitory concentration of the compound against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123433(7-{[Methanesulfonyl-(2'-sulfamoyl-biphenyl-4-yl)-a...)
Affinity DataIC50:  153nMAssay Description:Inhibitory concentration of the compound to factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAnionic trypsin-2(Rattus norvegicus)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123413(2-[({4-[1-(1-Imino-ethyl)-piperidin-4-yloxy]-pheny...)
Affinity DataIC50:  167nMAssay Description:Inhibitory concentration of the compound against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123430(3'-{[Methanesulfonyl-(2'-sulfamoyl-biphenyl-4-yl)-...)
Affinity DataIC50:  191nMAssay Description:Inhibitory concentration of the compound to factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAnionic trypsin-2(Rattus norvegicus)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123429(((3'-Carbamimidoyl-biphenyl-3-ylmethyl)-{4-[1-(1-i...)
Affinity DataIC50:  269nMAssay Description:Inhibitory concentration of the compound against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAnionic trypsin-2(Rattus norvegicus)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123425(((3'-Carbamimidoyl-biphenyl-3-ylmethyl)-{4-[1-(1-i...)
Affinity DataIC50:  292nMAssay Description:Inhibitory concentration of the compound against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAnionic trypsin-2(Rattus norvegicus)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123415(3'-[({4-[1-(1-Imino-ethyl)-piperidin-4-yloxy]-phen...)
Affinity DataIC50:  360nMAssay Description:Inhibitory concentration of the compound against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123434(3-(5-{[Methanesulfonyl-(2'-sulfamoyl-biphenyl-4-yl...)
Affinity DataIC50:  500nMAssay Description:Inhibitory concentration of the compound to factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAnionic trypsin-2(Rattus norvegicus)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123408(4'-[({4-[1-(1-Imino-ethyl)-piperidin-4-yloxy]-phen...)
Affinity DataIC50:  769nMAssay Description:Inhibitory concentration of the compound against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123412(1-Ethyl-2-{7-[1-(1-imino-ethyl)-piperidin-4-yloxy]...)
Affinity DataIC50:  877nMAssay Description:Inhibition of factor IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123426(2-{7-[1-(1-Imino-ethyl)-piperidin-4-yloxy]-3-oxo-2...)
Affinity DataIC50:  882nMAssay Description:Inhibition of factor IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123423(3-{3-[({4-[1-(1-Imino-ethyl)-piperidin-4-yloxy]-ph...)
Affinity DataIC50:  934nMAssay Description:Inhibitory concentration of the compound to factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123406(7-({Methanesulfonyl-[4-(pyrrolidine-1-carbonyl)-ph...)
Affinity DataIC50:  1.05E+3nMAssay Description:Inhibitory concentration of the compound to factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123418(7-[({4-[4-(1-Imino-ethyl)-piperazine-1-carbonyl]-p...)
Affinity DataIC50:  1.57E+3nMAssay Description:Inhibitory concentration of the compound to factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAnionic trypsin-2(Rattus norvegicus)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123423(3-{3-[({4-[1-(1-Imino-ethyl)-piperidin-4-yloxy]-ph...)
Affinity DataIC50:  2.11E+3nMAssay Description:Inhibitory concentration of the compound against trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123432(3-(3-{[Methanesulfonyl-(2'-sulfamoyl-biphenyl-4-yl...)
Affinity DataIC50:  3.93E+3nMAssay Description:Inhibitory concentration of the compound to factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123424((S)-1-{4-[(7-Carbamimidoyl-naphthalen-2-ylmethyl)-...)
Affinity DataIC50:  4.06E+3nMAssay Description:Inhibitory concentration of the compound to factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123410(3-{5-[({4-[1-(1-Imino-ethyl)-piperidin-4-yloxy]-ph...)
Affinity DataIC50:  6.92E+3nMAssay Description:Inhibitory concentration of the compound to factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123411(2'-[({4-[1-(1-Imino-ethyl)-piperidin-4-yloxy]-phen...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibitory concentration of the compound to factor XaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123427(3'-{7-[1-(1-Imino-ethyl)-piperidin-4-yloxy]-3-oxo-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of factor IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50123421(3-{5-[({4-[1-(1-Imino-ethyl)-piperidin-4-yloxy]-ph...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of factor IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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