Compile Data Set for Download or QSAR
maximum 50k data
Found 67 Enz. Inhib. hit(s) with all data for entry = 50016917
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50175210(CHEMBL199438 | N-(4-(4-amino-1-(1-(tetrahydro-2H-p...)
Affinity DataIC50:  13nMAssay Description:Inhibitory activity against anti-CD3 mAb-induced IL2 production in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50175200(CHEMBL371295 | N-(4-(4-amino-1-(1-(1-methylpiperid...)
Affinity DataIC50:  20nMAssay Description:Inhibitory activity against anti-CD3 mAb-induced IL2 production in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50175200(CHEMBL371295 | N-(4-(4-amino-1-(1-(1-methylpiperid...)
Affinity DataIC50:  23nMAssay Description:Inhibitory activity against lckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50175209(CHEMBL198136 | N-(4-(4-amino-1-(1-methylpiperidin-...)
Affinity DataIC50:  30nMAssay Description:Inhibitory activity against anti-CD3 mAb-induced IL2 production in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50175199(CHEMBL371459 | N-(4-(1-(1-(1-acetylpiperidin-4-yl)...)
Affinity DataIC50:  30nMAssay Description:Inhibitory activity against anti-CD3 mAb-induced IL2 production in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50175197(CHEMBL199369 | N-(4-(4-amino-1-(1-(tetrahydro-2H-p...)
Affinity DataIC50:  35nMAssay Description:Inhibitory activity against anti-CD3 mAb-induced IL2 production in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50175198(CHEMBL198239 | N-(4-(4-amino-1-(1-(tetrahydro-2H-p...)
Affinity DataIC50:  40nMAssay Description:Inhibitory activity against anti-CD3 mAb-induced IL2 production in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50175205(CHEMBL200587 | N-(4-(4-amino-1-(piperidin-4-yl)-1H...)
Affinity DataIC50:  50nMAssay Description:Inhibitory activity against anti-CD3 mAb-induced IL2 production in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50175201(CHEMBL382939 | N-(4-(4-amino-1-(1-(tetrahydro-2H-p...)
Affinity DataIC50:  54nMAssay Description:Inhibitory activity against anti-CD3 mAb-induced IL2 production in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50175210(CHEMBL199438 | N-(4-(4-amino-1-(1-(tetrahydro-2H-p...)
Affinity DataIC50:  54nMAssay Description:Inhibitory activity against lckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50175195(CHEMBL370773 | N-(4-(1-(1-(1-acetylpiperidin-4-yl)...)
Affinity DataIC50:  74nMAssay Description:Inhibitory activity against lckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50175205(CHEMBL200587 | N-(4-(4-amino-1-(piperidin-4-yl)-1H...)
Affinity DataIC50:  80nMAssay Description:Inhibitory activity against lckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50175196(A-770041 | CHEMBL197603 | N-(4-(1-(4-(4-acetylpipe...)
Affinity DataIC50:  80nMAssay Description:Inhibitory activity against anti-CD3 mAb-induced IL2 production in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50175199(CHEMBL371459 | N-(4-(1-(1-(1-acetylpiperidin-4-yl)...)
Affinity DataIC50:  93nMAssay Description:Inhibitory activity against lckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50175198(CHEMBL198239 | N-(4-(4-amino-1-(1-(tetrahydro-2H-p...)
Affinity DataIC50:  102nMAssay Description:Inhibitory activity against lckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50175209(CHEMBL198136 | N-(4-(4-amino-1-(1-methylpiperidin-...)
Affinity DataIC50:  106nMAssay Description:Inhibitory activity against lckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50175197(CHEMBL199369 | N-(4-(4-amino-1-(1-(tetrahydro-2H-p...)
Affinity DataIC50:  106nMAssay Description:Inhibitory activity against lckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50175207(A-641359 | CHEMBL381203 | N-(4-(4-amino-1-(1-(tetr...)
Affinity DataIC50:  107nMAssay Description:Inhibitory activity against lckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50175207(A-641359 | CHEMBL381203 | N-(4-(4-amino-1-(1-(tetr...)
Affinity DataIC50:  107nMAssay Description:Inhibitory activity against lckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50175196(A-770041 | CHEMBL197603 | N-(4-(1-(4-(4-acetylpipe...)
Affinity DataIC50:  147nMAssay Description:Inhibitory activity against lckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50175201(CHEMBL382939 | N-(4-(4-amino-1-(1-(tetrahydro-2H-p...)
Affinity DataIC50:  318nMAssay Description:Inhibitory activity against lckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50175211(CHEMBL373054 | N-(4-(4-amino-1-(1-benzylpiperidin-...)
Affinity DataIC50:  341nMAssay Description:Inhibitory activity against lckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50175211(CHEMBL373054 | N-(4-(4-amino-1-(1-benzylpiperidin-...)
Affinity DataIC50:  540nMAssay Description:Inhibitory activity against anti-CD3 mAb-induced IL2 production in human whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50175200(CHEMBL371295 | N-(4-(4-amino-1-(1-(1-methylpiperid...)
Affinity DataIC50:  1.07E+3nMAssay Description:Inhibitory activity against fynMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50175196(A-770041 | CHEMBL197603 | N-(4-(1-(4-(4-acetylpipe...)
Affinity DataIC50:  1.18E+3nMAssay Description:Inhibitory activity against lynMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase HCK(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50175196(A-770041 | CHEMBL197603 | N-(4-(1-(4-(4-acetylpipe...)
Affinity DataIC50:  1.22E+3nMAssay Description:Inhibitory activity against hckMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50175212(CHEMBL200424 | N-(4-(4-amino-1-(1-(tetrahydro-2H-p...)
Affinity DataIC50:  2.35E+3nMAssay Description:Inhibitory activity against lckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50175203(CHEMBL440213 | N-(4-(4-amino-1-(1-(tetrahydro-2H-p...)
Affinity DataIC50:  3.48E+3nMAssay Description:Inhibitory activity against lckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50175202(CHEMBL370383 | N-(4-(4-amino-1-(1-(tetrahydro-2H-p...)
Affinity DataIC50:  8.96E+3nMAssay Description:Inhibitory activity against lckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50175196(A-770041 | CHEMBL197603 | N-(4-(1-(4-(4-acetylpipe...)
Affinity DataIC50:  9.05E+3nMAssay Description:Inhibitory activity against srcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50175208(CHEMBL199816 | N-(4-(4-amino-1-(1-(tetrahydro-2H-p...)
Affinity DataIC50:  9.18E+3nMAssay Description:Inhibitory activity against lckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50175210(CHEMBL199438 | N-(4-(4-amino-1-(1-(tetrahydro-2H-p...)
Affinity DataIC50:  1.36E+4nMAssay Description:Inhibitory activity against fynMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fgr(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50175196(A-770041 | CHEMBL197603 | N-(4-(1-(4-(4-acetylpipe...)
Affinity DataIC50:  1.41E+4nMAssay Description:Inhibitory activity against fgrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50175195(CHEMBL370773 | N-(4-(1-(1-(1-acetylpiperidin-4-yl)...)
Affinity DataIC50:  1.72E+4nMAssay Description:Inhibitory activity against srcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50175204(CHEMBL370670 | N-(4-(4-amino-1-(1-(tetrahydro-2H-p...)
Affinity DataIC50:  2.32E+4nMAssay Description:Inhibitory activity against lckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50175196(A-770041 | CHEMBL197603 | N-(4-(1-(4-(4-acetylpipe...)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibitory activity against ITKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50175196(A-770041 | CHEMBL197603 | N-(4-(1-(4-(4-acetylpipe...)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibitory activity against ZAP70More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50175196(A-770041 | CHEMBL197603 | N-(4-(1-(4-(4-acetylpipe...)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibitory activity against JAK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50175196(A-770041 | CHEMBL197603 | N-(4-(1-(4-(4-acetylpipe...)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibitory activity against IKK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50175196(A-770041 | CHEMBL197603 | N-(4-(1-(4-(4-acetylpipe...)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibitory activity against TYK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 8(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50175196(A-770041 | CHEMBL197603 | N-(4-(1-(4-(4-acetylpipe...)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibitory activity against COTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50175196(A-770041 | CHEMBL197603 | N-(4-(1-(4-(4-acetylpipe...)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibitory activity against IRAK4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50175196(A-770041 | CHEMBL197603 | N-(4-(1-(4-(4-acetylpipe...)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibitory activity against SykMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-dependent protein kinase catalytic subunit alpha/beta/gamma(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50175196(A-770041 | CHEMBL197603 | N-(4-(1-(4-(4-acetylpipe...)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibitory activity against PKAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50175196(A-770041 | CHEMBL197603 | N-(4-(1-(4-(4-acetylpipe...)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibitory activity against MK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetO94806/P05129/P05771/P17252/P24723/P41743/Q02156/Q04759/Q05513/Q05655/Q15139(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50175196(A-770041 | CHEMBL197603 | N-(4-(1-(4-(4-acetylpipe...)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibitory activity against PKCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50175196(A-770041 | CHEMBL197603 | N-(4-(1-(4-(4-acetylpipe...)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibitory activity against p38More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50175196(A-770041 | CHEMBL197603 | N-(4-(1-(4-(4-acetylpipe...)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibitory activity against IKK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50175203(CHEMBL440213 | N-(4-(4-amino-1-(1-(tetrahydro-2H-p...)
Affinity DataIC50:  3.25E+4nMAssay Description:Inhibitory activity against fynMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50175196(A-770041 | CHEMBL197603 | N-(4-(1-(4-(4-acetylpipe...)
Affinity DataIC50:  4.41E+4nMAssay Description:Inhibitory activity against fynMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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