Compile Data Set for Download or QSAR
maximum 50k data
Found 40 Enz. Inhib. hit(s) with all data for entry = 50031014
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Sumitomo Chemical

Curated by ChEMBL
LigandPNGBDBM50305335(7-hydroxy-4-((6-methylpyridin-2-ylthio)methyl)-2H-...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of human 17beta-HSD3 expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Sumitomo Chemical

Curated by ChEMBL
LigandPNGBDBM50305325(7-hydroxy-4-((pyridin-2-ylthio)methyl)-2H-chromen-...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human 17beta-HSD3 expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Sumitomo Chemical

Curated by ChEMBL
LigandPNGBDBM50305336(7-hydroxy-4-(2-(6-methylpyridin-2-yl)ethyl)-2H-chr...)
Affinity DataIC50:  8nMAssay Description:Inhibition of human 17beta-HSD3 expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Sumitomo Chemical

Curated by ChEMBL
LigandPNGBDBM50305330(7-hydroxy-4-((thiazol-2-ylthio)methyl)-2H-chromen-...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human 17beta-HSD3 expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Sumitomo Chemical

Curated by ChEMBL
LigandPNGBDBM50305320(7-hydroxy-4-phenethyl-2H-chromen-2-one | CHEMBL592...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human 17beta-HSD3 expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Sumitomo Chemical

Curated by ChEMBL
LigandPNGBDBM50305338(3-fluoro-7-hydroxy-4-((6-methylpyridin-2-ylthio)me...)
Affinity DataIC50:  27nMAssay Description:Inhibition of human 17beta-HSD3 expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Sumitomo Chemical

Curated by ChEMBL
LigandPNGBDBM50305316(3-benzyl-7-hydroxy-4-(trifluoromethyl)-2H-chromen-...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human 17beta-HSD3 expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Sumitomo Chemical

Curated by ChEMBL
LigandPNGBDBM50305339(3-chloro-7-hydroxy-4-((6-methylpyridin-2-ylthio)me...)
Affinity DataIC50:  47nMAssay Description:Inhibition of human 17beta-HSD3 expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Sumitomo Chemical

Curated by ChEMBL
LigandPNGBDBM50305309(7-hydroxy-4-propyl-2H-chromen-2-one | CHEMBL605407)
Affinity DataIC50:  59nMAssay Description:Inhibition of human 17beta-HSD3 expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Sumitomo Chemical

Curated by ChEMBL
LigandPNGBDBM50305333(7-hydroxy-4-((4-nitropyridin-2-ylthio)methyl)-2H-c...)
Affinity DataIC50:  88nMAssay Description:Inhibition of human 17beta-HSD3 expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Sumitomo Chemical

Curated by ChEMBL
LigandPNGBDBM50305332(7-hydroxy-4-((1-methyl-1H-imidazol-2-ylthio)methyl...)
Affinity DataIC50:  91nMAssay Description:Inhibition of human 17beta-HSD3 expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Sumitomo Chemical

Curated by ChEMBL
LigandPNGBDBM50305322(7-hydroxy-4-(phenylthiomethyl)-2H-chromen-2-one | ...)
Affinity DataIC50:  93nMAssay Description:Inhibition of human 17beta-HSD3 expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Sumitomo Chemical

Curated by ChEMBL
LigandPNGBDBM50305331(7-hydroxy-4-((thiazolidin-2-ylthio)methyl)-2H-chro...)
Affinity DataIC50:  96nMAssay Description:Inhibition of human 17beta-HSD3 expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Sumitomo Chemical

Curated by ChEMBL
LigandPNGBDBM50305318(3-Chloro-4-methyl-7-hydroxy-2H-2-chromenone | 3-ch...)
Affinity DataIC50:  100nMAssay Description:Inhibition of human 17beta-HSD3 expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Sumitomo Chemical

Curated by ChEMBL
LigandPNGBDBM50305308(4-ethyl-7-hydroxy-2H-chromen-2-one | CHEMBL600114)
Affinity DataIC50:  100nMAssay Description:Inhibition of human 17beta-HSD3 expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Sumitomo Chemical

Curated by ChEMBL
LigandPNGBDBM50305310(7-Hydroxy-4-trifluoromethyl-chromen-2-one | 7-hydr...)
Affinity DataIC50:  190nMAssay Description:Inhibition of human 17beta-HSD3 expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Sumitomo Chemical

Curated by ChEMBL
LigandPNGBDBM50305315(3-benzyl-7-hydroxy-4-methyl-2H-chromen-2-one | CHE...)
Affinity DataIC50:  200nMAssay Description:Inhibition of human 17beta-HSD3 expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Sumitomo Chemical

Curated by ChEMBL
LigandPNGBDBM50305329(4-((1,3,4-thiadiazol-2-ylthio)methyl)-7-hydroxy-2H...)
Affinity DataIC50:  200nMAssay Description:Inhibition of human 17beta-HSD3 expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Sumitomo Chemical

Curated by ChEMBL
LigandPNGBDBM50282524(7-Hydroxy-3,4-dimethyl-chromen-2-one | 7-hydroxy-3...)
Affinity DataIC50:  210nMAssay Description:Inhibition of human 17beta-HSD3 expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Sumitomo Chemical

Curated by ChEMBL
LigandPNGBDBM50305334(7-hydroxy-4-((5-(trifluoromethyl)pyridin-2-ylthio)...)
Affinity DataIC50:  230nMAssay Description:Inhibition of human 17beta-HSD3 expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Sumitomo Chemical

Curated by ChEMBL
LigandPNGBDBM50305314(7-hydroxy-4-methyl-3-propyl-2H-chromen-2-one | CHE...)
Affinity DataIC50:  240nMAssay Description:Inhibition of human 17beta-HSD3 expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Sumitomo Chemical

Curated by ChEMBL
LigandPNGBDBM50305340(7-hydroxy-3-((pyridin-2-ylthio)methyl)-4-(trifluor...)
Affinity DataIC50:  320nMAssay Description:Inhibition of human 17beta-HSD3 expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Sumitomo Chemical

Curated by ChEMBL
LigandPNGBDBM50305328(7-hydroxy-4-((thiophen-2-ylthio)methyl)-2H-chromen...)
Affinity DataIC50:  420nMAssay Description:Inhibition of human 17beta-HSD3 expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Sumitomo Chemical

Curated by ChEMBL
LigandPNGBDBM50104891(7-Hydroxy-4-phenyl-chromen-2-one | 7-hydroxy-4-phe...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human 17beta-HSD3 expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Sumitomo Chemical

Curated by ChEMBL
LigandPNGBDBM50305319(7-hydroxy-4-methyl-2-oxo-2H-chromene-3-carbonitril...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human 17beta-HSD3 expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Sumitomo Chemical

Curated by ChEMBL
LigandPNGBDBM50305317(3-fluoro-7-hydroxy-4-methyl-2H-chromen-2-one | CHE...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human 17beta-HSD3 expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Sumitomo Chemical

Curated by ChEMBL
LigandPNGBDBM50305313(7-hydroxy-3-methyl-2H-chromen-2-one | CHEMBL593424)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human 17beta-HSD3 expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Sumitomo Chemical

Curated by ChEMBL
LigandPNGBDBM50022178(4-Methyl-7-hydroxycoumarin | 4-methylumbelliferone...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human 17beta-HSD3 expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Sumitomo Chemical

Curated by ChEMBL
LigandPNGBDBM50305327(7-hydroxy-4-((pyrimidin-2-ylthio)methyl)-2H-chrome...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human 17beta-HSD3 expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Sumitomo Chemical

Curated by ChEMBL
LigandPNGBDBM50305316(3-benzyl-7-hydroxy-4-(trifluoromethyl)-2H-chromen-...)
Affinity DataIC50:  1.00E+3nMAssay Description:Agonist activity at ER by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Sumitomo Chemical

Curated by ChEMBL
LigandPNGBDBM50305337(7-hydroxy-4-(2-(6-methylpyridin-2-yloxy)ethyl)-2H-...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human 17beta-HSD3 expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Sumitomo Chemical

Curated by ChEMBL
LigandPNGBDBM50305323(7-hydroxy-4-((phenylamino)methyl)-2H-chromen-2-one...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of human 17beta-HSD3 expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Sumitomo Chemical

Curated by ChEMBL
LigandPNGBDBM50305311(7-hydroxy-4-(methoxymethyl)-2H-chromen-2-one | CHE...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of human 17beta-HSD3 expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Sumitomo Chemical

Curated by ChEMBL
LigandPNGBDBM50305326(7-hydroxy-4-((pyridin-4-ylthio)methyl)-2H-chromen-...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of human 17beta-HSD3 expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Sumitomo Chemical

Curated by ChEMBL
LigandPNGBDBM50305316(3-benzyl-7-hydroxy-4-(trifluoromethyl)-2H-chromen-...)
Affinity DataIC50:  6.00E+3nMAssay Description:Antagonist activity at AR by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Sumitomo Chemical

Curated by ChEMBL
LigandPNGBDBM50305324(7-hydroxy-4-((methyl(phenyl)amino)methyl)-2H-chrom...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of human 17beta-HSD3 expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Sumitomo Chemical

Curated by ChEMBL
LigandPNGBDBM50305312(4-benzyl-7-hydroxy-2H-chromen-2-one | CHEMBL592757)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human 17beta-HSD3 expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Sumitomo Chemical

Curated by ChEMBL
LigandPNGBDBM50305321(7-hydroxy-4-(phenoxymethyl)-2H-chromen-2-one | CHE...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human 17beta-HSD3 expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Sumitomo Chemical

Curated by ChEMBL
LigandPNGBDBM50305335(7-hydroxy-4-((6-methylpyridin-2-ylthio)methyl)-2H-...)
Affinity DataIC50:  5.00E+4nMAssay Description:Agonist activity at ER by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Sumitomo Chemical

Curated by ChEMBL
LigandPNGBDBM50305335(7-hydroxy-4-((6-methylpyridin-2-ylthio)methyl)-2H-...)
Affinity DataIC50:  5.00E+4nMAssay Description:Antagonist activity at AR by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed