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Found 170 Enz. Inhib. hit(s) with all data for entry = 50040833
TargetNeutrophil elastase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50095523(CHEMBL285231 | [(S)-2-methyl-1-((S)-2-{(S)-2-methy...)
Affinity DataKi:  0.0250nMAssay Description:Inhibition of human neutrophil elastaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50204512(2-(7-phenylheptanoyl)oxazole-5-carbonitrile | CHEM...)
Affinity DataKi:  0.400nMAssay Description:Inhibition of FAAHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50095526(CHEMBL24058 | [(S)-2-methyl-1-((S)-2-{(S)-2-methyl...)
Affinity DataKi:  0.490nMAssay Description:Inhibition of human neutrophil elastaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50400823(CHEMBL2204343)
Affinity DataKi:  0.550nMAssay Description:Inhibition of human dopamine D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50400837(CHEMBL2205678)
Affinity DataKi:  0.600nMAssay Description:Inhibition of human neutrophil elastaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50204483(7-phenyl-1-(5-(trifluoromethyl)oxazol-2-yl)heptan-...)
Affinity DataKi:  0.800nMAssay Description:Inhibition of FAAHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50204490(CHEMBL220784 | methyl 2-(7-phenylheptanoyl)oxazole...)
Affinity DataKi:  0.900nMAssay Description:Inhibition of FAAHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50193921(3-(2-(naphthalen-2-ylmethyl)phenyl)-N-(thiophen-2-...)
Affinity DataKi:  1.10nMAssay Description:Inhibition of EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50036058(CHEMBL354883 | benzyl (S)-1-((S)-2-(((S)-1,1,1-tri...)
Affinity DataKi:  1.60nMAssay Description:Inhibition of human neutrophil elastaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  1.90nMAssay Description:Inhibition of sigma 1 receptorMore data for this Ligand-Target Pair
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50400835(CHEMBL219660)
Affinity DataKi:  2nMAssay Description:Inhibition of FAAHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50400836(CHEMBL219659)
Affinity DataKi:  2nMAssay Description:Inhibition of FAAHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50400818(CHEMBL2204339)
Affinity DataKi:  2.10nMAssay Description:Inhibition of EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  2.84nMAssay Description:Inhibition of human dopamine D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50204475(1-(5-bromooxazol-2-yl)-7-phenylheptan-1-one | CHEM...)
Affinity DataKi:  3nMAssay Description:Inhibition of FAAHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50400832(CHEMBL220555)
Affinity DataKi:  3nMAssay Description:Inhibition of FAAHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50031199(((S)-1-{(S)-2-[(S)-1-(Benzooxazole-2-carbonyl)-2-m...)
Affinity DataKi:  3nMAssay Description:Inhibition of human neutrophil elastaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50400823(CHEMBL2204343)
Affinity DataKi:  3.40nMAssay Description:Inhibition of sigma 1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50400833(CHEMBL220378)
Affinity DataKi:  3.5nMAssay Description:Inhibition of FAAHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50400823(CHEMBL2204343)
Affinity DataKi:  4.73nMAssay Description:Inhibition of human dopamine D3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50204525(2-(7-phenylheptanoyl)oxazole-5-carboxamide | CHEMB...)
Affinity DataKi:  5nMAssay Description:Inhibition of FAAHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50400831(CHEMBL220613)
Affinity DataKi:  5nMAssay Description:Inhibition of FAAHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50400834(CHEMBL220727)
Affinity DataKi:  6nMAssay Description:Inhibition of FAAHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50154726(6-(4-Fluoro-phenyl)-1-oxo-1,2,3,4-tetrahydro-[1,4]...)
Affinity DataKi:  6nMAssay Description:Inhibition of human PARP-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50120724(2-Phenyl-1,3,4,5-tetrahydro-azepino[5,4,3-cd]indol...)
Affinity DataKi:  6nMAssay Description:Inhibition of human PARP-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50400820(CHEMBL2204337)
Affinity DataKi:  6.70nMAssay Description:Inhibition of EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50154739(6-(4-Chloro-phenyl)-1-oxo-1,2,3,4-tetrahydro-[1,4]...)
Affinity DataKi:  7.5nMAssay Description:Inhibition of human PARP-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  7.94nMAssay Description:Inhibition of human dopamine D4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50154759(6-(4-Fluoro-phenyl)-7-(1-hydroxyimino-ethyl)-3,4-d...)
Affinity DataKi:  9.10nMAssay Description:Inhibition of human PARP-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50154735(1-Oxo-1,2,3,4-tetrahydro-[1,4]diazepino[6,7,1-hi]i...)
Affinity DataKi:  9.40nMAssay Description:Inhibition of human PARP-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50400817(CHEMBL2204340)
Affinity DataKi:  9.90nMAssay Description:Inhibition of EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  10.4nMAssay Description:Inhibition of human dopamine D3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50154723(6-(4-Fluoro-phenyl)-3,4-dihydro-2H-[1,4]diazepino[...)
Affinity DataKi:  11nMAssay Description:Inhibition of human PARP-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50165843(4'-{[3-(3,3,3-Trifluoro-propionylamino)-pyridin-2-...)
Affinity DataKi:  11.8nMAssay Description:Antagonist activity at Bradykinin B1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50400823(CHEMBL2204343)
Affinity DataKi:  14.1nMAssay Description:Inhibition of human dopamine D4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1B) dopamine receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50400823(CHEMBL2204343)
Affinity DataKi:  16.6nMAssay Description:Inhibition of human dopamine D5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50400819(CHEMBL2204338)
Affinity DataKi:  17nMAssay Description:Inhibition of EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50400862(CHEMBL2205015)
Affinity DataKi:  19nMAssay Description:Inhibition of FKBP12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50036051(((S)-1-{(S)-2-[(S)-1-(Benzothiazole-2-carbonyl)-2-...)
Affinity DataKi:  25nMAssay Description:Inhibition of human neutrophil elastaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50400830(CHEMBL219954)
Affinity DataKi:  25nMAssay Description:Inhibition of FAAHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50036040(((S)-2-Methyl-1-{(S)-2-[(S)-2-methyl-1-(oxazole-2-...)
Affinity DataKi:  28nMAssay Description:Inhibition of human neutrophil elastaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50204506(2-(7-phenylheptanoyl)oxazole-5-carboxylic acid | C...)
Affinity DataKi:  30nMAssay Description:Inhibition of FAAHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50374375(CHEMBL373906)
Affinity DataKi:  30nMAssay Description:Inhibition of FAAHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1B) dopamine receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  38nMAssay Description:Inhibition of human dopamine D5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50154755(7-{1-[(E)-Hydroxyimino]-ethyl}-3,4-dihydro-2H-[1,4...)
Affinity DataKi:  39nMAssay Description:Inhibition of human PARP-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50400843(CHEMBL2205679)
Affinity DataKi:  39nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50400818(CHEMBL2204339)
Affinity DataKi:  41nMAssay Description:Inhibition of EP3 receptor in presence of 0.005 % HASMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50036057(CHEMBL165525 | benzyl (S)-1-((S)-2-(((S)-3-methyl-...)
Affinity DataKi:  41nMAssay Description:Inhibition of human neutrophil elastaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50204493(1-(oxazol-2-yl)-7-phenylheptan-1-one | CHEMBL22012...)
Affinity DataKi:  48nMAssay Description:Inhibition of FAAHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50182456(CHEMBL202089 | methyl 4'-{[({1-[(3,3,3-trifluoropr...)
Affinity DataKi:  63nMAssay Description:Antagonist activity at Bradykinin B1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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