Compile Data Set for Download or QSAR
maximum 50k data
Found 32 Enz. Inhib. hit(s) with all data for entry = 50033771
TargetAcetylcholinesterase(Homo sapiens (Human))
Institut F£R Molekulare Physiologie

Curated by ChEMBL
LigandPNGBDBM50351015(CHEMBL1819176)
Affinity DataKi:  1nMAssay Description:Mixed-type inhibition of human AChE assessed as hydrolysis of acetylthiocholine by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Institut F£R Molekulare Physiologie

Curated by ChEMBL
LigandPNGBDBM8963(CHEMBL32823 | Homodimeric Tacrine Analog 3b | N-[7...)
Affinity DataIC50:  0.810nMAssay Description:Mixed-type inhibition of human AChE assessed as hydrolysis of acetylthiocholine by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Institut F£R Molekulare Physiologie

Curated by ChEMBL
LigandPNGBDBM50351015(CHEMBL1819176)
Affinity DataIC50:  1.10nMAssay Description:Mixed-type inhibition of human AChE assessed as hydrolysis of acetylthiocholine by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Institut F£R Molekulare Physiologie

Curated by ChEMBL
LigandPNGBDBM8963(CHEMBL32823 | Homodimeric Tacrine Analog 3b | N-[7...)
Affinity DataIC50:  5.70nMAssay Description:Inhibition of human serum recombinant BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Institut F£R Molekulare Physiologie

Curated by ChEMBL
LigandPNGBDBM50351016(CHEMBL1819177)
Affinity DataIC50:  12nMAssay Description:Mixed-type inhibition of human AChE assessed as hydrolysis of acetylthiocholine by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Institut F£R Molekulare Physiologie

Curated by ChEMBL
LigandPNGBDBM50351020(CHEMBL1819175)
Affinity DataIC50:  14nMAssay Description:Mixed-type inhibition of human AChE assessed as hydrolysis of acetylthiocholine by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Institut F£R Molekulare Physiologie

Curated by ChEMBL
LigandPNGBDBM50351013(CHEMBL1819173)
Affinity DataIC50:  15nMAssay Description:Inhibition of human serum recombinant BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Institut F£R Molekulare Physiologie

Curated by ChEMBL
LigandPNGBDBM50351011(CHEMBL1819171)
Affinity DataIC50:  17nMAssay Description:Mixed-type inhibition of human AChE assessed as hydrolysis of acetylthiocholine by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Institut F£R Molekulare Physiologie

Curated by ChEMBL
LigandPNGBDBM50351020(CHEMBL1819175)
Affinity DataIC50:  25nMAssay Description:Inhibition of human serum recombinant BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Institut F£R Molekulare Physiologie

Curated by ChEMBL
LigandPNGBDBM50351013(CHEMBL1819173)
Affinity DataIC50:  28nMAssay Description:Mixed-type inhibition of human AChE assessed as hydrolysis of acetylthiocholine by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Institut F£R Molekulare Physiologie

Curated by ChEMBL
LigandPNGBDBM50351019(CHEMBL1819180)
Affinity DataIC50:  29nMAssay Description:Inhibition of human serum recombinant BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Institut F£R Molekulare Physiologie

Curated by ChEMBL
LigandPNGBDBM50351012(CHEMBL1819172)
Affinity DataIC50:  34nMAssay Description:Mixed-type inhibition of human AChE assessed as hydrolysis of acetylthiocholine by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Institut F£R Molekulare Physiologie

Curated by ChEMBL
LigandPNGBDBM50351012(CHEMBL1819172)
Affinity DataIC50:  38nMAssay Description:Inhibition of human serum recombinant BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Institut F£R Molekulare Physiologie

Curated by ChEMBL
LigandPNGBDBM50351018(CHEMBL1819179)
Affinity DataIC50:  41nMAssay Description:Inhibition of human serum recombinant BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Institut F£R Molekulare Physiologie

Curated by ChEMBL
LigandPNGBDBM50351011(CHEMBL1819171)
Affinity DataIC50:  43nMAssay Description:Inhibition of human serum recombinant BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Institut F£R Molekulare Physiologie

Curated by ChEMBL
LigandPNGBDBM50351010(CHEMBL1819170)
Affinity DataIC50:  45nMAssay Description:Mixed-type inhibition of human AChE assessed as hydrolysis of acetylthiocholine by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Institut F£R Molekulare Physiologie

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  50nMAssay Description:Inhibition of human serum recombinant BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
TargetCholinesterase(Homo sapiens (Human))
Institut F£R Molekulare Physiologie

Curated by ChEMBL
LigandPNGBDBM50351015(CHEMBL1819176)
Affinity DataIC50:  64nMAssay Description:Inhibition of human serum recombinant BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Institut F£R Molekulare Physiologie

Curated by ChEMBL
LigandPNGBDBM50351009(CHEMBL1819169)
Affinity DataIC50:  69nMAssay Description:Mixed-type inhibition of human AChE assessed as hydrolysis of acetylthiocholine by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Institut F£R Molekulare Physiologie

Curated by ChEMBL
LigandPNGBDBM50351010(CHEMBL1819170)
Affinity DataIC50:  91nMAssay Description:Inhibition of human serum recombinant BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Institut F£R Molekulare Physiologie

Curated by ChEMBL
LigandPNGBDBM50351014(CHEMBL1819174)
Affinity DataIC50:  101nMAssay Description:Inhibition of human serum recombinant BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Institut F£R Molekulare Physiologie

Curated by ChEMBL
LigandPNGBDBM50351009(CHEMBL1819169)
Affinity DataIC50:  101nMAssay Description:Inhibition of human serum recombinant BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Institut F£R Molekulare Physiologie

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  250nMAssay Description:Mixed-type inhibition of human AChE assessed as hydrolysis of acetylthiocholine by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Institut F£R Molekulare Physiologie

Curated by ChEMBL
LigandPNGBDBM50351018(CHEMBL1819179)
Affinity DataIC50:  258nMAssay Description:Mixed-type inhibition of human AChE assessed as hydrolysis of acetylthiocholine by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Institut F£R Molekulare Physiologie

Curated by ChEMBL
LigandPNGBDBM50351014(CHEMBL1819174)
Affinity DataIC50:  283nMAssay Description:Mixed-type inhibition of human AChE assessed as hydrolysis of acetylthiocholine by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Institut F£R Molekulare Physiologie

Curated by ChEMBL
LigandPNGBDBM50351017(CHEMBL1819178)
Affinity DataIC50:  310nMAssay Description:Mixed-type inhibition of human AChE assessed as hydrolysis of acetylthiocholine by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Institut F£R Molekulare Physiologie

Curated by ChEMBL
LigandPNGBDBM50351019(CHEMBL1819180)
Affinity DataIC50:  400nMAssay Description:Inhibition of BACE1 expressed in baculovirus assessed as inhibition of amyloid beta-42 production after 60 mins by spectrofluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Institut F£R Molekulare Physiologie

Curated by ChEMBL
LigandPNGBDBM50351019(CHEMBL1819180)
Affinity DataIC50:  455nMAssay Description:Mixed-type inhibition of human AChE assessed as hydrolysis of acetylthiocholine by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Institut F£R Molekulare Physiologie

Curated by ChEMBL
LigandPNGBDBM50351015(CHEMBL1819176)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of BACE1 expressed in baculovirus assessed as inhibition of amyloid beta-42 production after 60 mins by spectrofluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Institut F£R Molekulare Physiologie

Curated by ChEMBL
LigandPNGBDBM50351016(CHEMBL1819177)
Affinity DataIC50:  1.66E+3nMAssay Description:Inhibition of human serum recombinant BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Institut F£R Molekulare Physiologie

Curated by ChEMBL
LigandPNGBDBM50351017(CHEMBL1819178)
Affinity DataIC50:  7.28E+3nMAssay Description:Inhibition of human serum recombinant BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Institut F£R Molekulare Physiologie

Curated by ChEMBL
LigandPNGBDBM8963(CHEMBL32823 | Homodimeric Tacrine Analog 3b | N-[7...)
Affinity DataIC50:  7.50E+3nMAssay Description:Inhibition of BACE1 expressed in baculovirus assessed as inhibition of amyloid beta-42 production after 60 mins by spectrofluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed