Compile Data Set for Download or QSAR
maximum 50k data
Found 16 Enz. Inhib. hit(s) with all data for entry = 50046012
TargetMacrophage-stimulating protein receptor(Homo sapiens (Human))
Chemrf Laboratories

Curated by ChEMBL
LigandPNGBDBM50091030(CHEMBL3582033)
Affinity DataIC50:  10nMAssay Description:Inhibition of RON (unknown origin) transfected in 293T cells assessed as autophosporylated level by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage-stimulating protein receptor(Homo sapiens (Human))
Chemrf Laboratories

Curated by ChEMBL
LigandPNGBDBM50317323(CHEMBL1094718 | N-(3-fluoro-4-(2-(1-methyl-1H-imid...)
Affinity DataIC50:  12nMAssay Description:Inhibition of RON (unknown origin) transfected in 293T cells assessed as autophosporylated level by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage-stimulating protein receptor(Homo sapiens (Human))
Chemrf Laboratories

Curated by ChEMBL
LigandPNGBDBM50090969(CHEMBL3582034)
Affinity DataIC50:  13nMAssay Description:Inhibition of RON (unknown origin) transfected in 293T cells assessed as autophosporylated level by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage-stimulating protein receptor(Homo sapiens (Human))
Chemrf Laboratories

Curated by ChEMBL
LigandPNGBDBM50317324(CHEMBL1087984 | N-(4-(6,7-dimethoxyquinolin-4-ylox...)
Affinity DataIC50:  16nMAssay Description:Inhibition of RON (unknown origin) transfected in 293T cells assessed as autophosporylated level by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage-stimulating protein receptor(Homo sapiens (Human))
Chemrf Laboratories

Curated by ChEMBL
LigandPNGBDBM50090968(CHEMBL3582035)
Affinity DataIC50:  17nMAssay Description:Inhibition of RON (unknown origin) transfected in 293T cells assessed as autophosporylated level by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage-stimulating protein receptor(Homo sapiens (Human))
Chemrf Laboratories

Curated by ChEMBL
LigandPNGBDBM50317323(CHEMBL1094718 | N-(3-fluoro-4-(2-(1-methyl-1H-imid...)
Affinity DataIC50:  30nMAssay Description:Inhibition of RON phosphorylation in human PC3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage-stimulating protein receptor(Homo sapiens (Human))
Chemrf Laboratories

Curated by ChEMBL
LigandPNGBDBM50317323(CHEMBL1094718 | N-(3-fluoro-4-(2-(1-methyl-1H-imid...)
Affinity DataIC50:  30nMAssay Description:Inhibition of RON phosphorylation in human HT29 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage-stimulating protein receptor(Homo sapiens (Human))
Chemrf Laboratories

Curated by ChEMBL
LigandPNGBDBM50090966(CHEMBL3582037)
Affinity DataIC50:  44nMAssay Description:Inhibition of RON (unknown origin) transfected in 293T cells assessed as autophosporylated level by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage-stimulating protein receptor(Homo sapiens (Human))
Chemrf Laboratories

Curated by ChEMBL
LigandPNGBDBM50090967(CHEMBL3582036)
Affinity DataIC50:  95nMAssay Description:Inhibition of RON (unknown origin) transfected in 293T cells assessed as autophosporylated level by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage-stimulating protein receptor(Homo sapiens (Human))
Chemrf Laboratories

Curated by ChEMBL
LigandPNGBDBM50091026(CHEMBL3580678)
Affinity DataIC50:  580nMAssay Description:Inhibition of RON (unknown origin) transfected in 293T cells assessed as autophosporylated level by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Chemrf Laboratories

Curated by ChEMBL
LigandPNGBDBM50090968(CHEMBL3582035)
Affinity DataIC50:  670nMAssay Description:Inhibition of phosphorylation of c-Met in human MKN45 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Chemrf Laboratories

Curated by ChEMBL
LigandPNGBDBM50317324(CHEMBL1087984 | N-(4-(6,7-dimethoxyquinolin-4-ylox...)
Affinity DataIC50:  1.06E+3nMAssay Description:Inhibition of phosphorylation of c-Met in human MKN45 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Chemrf Laboratories

Curated by ChEMBL
LigandPNGBDBM50090969(CHEMBL3582034)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of phosphorylation of c-Met in human MKN45 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Chemrf Laboratories

Curated by ChEMBL
LigandPNGBDBM50090967(CHEMBL3582036)
Affinity DataIC50:  3.77E+3nMAssay Description:Inhibition of phosphorylation of c-Met in human MKN45 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Chemrf Laboratories

Curated by ChEMBL
LigandPNGBDBM50090966(CHEMBL3582037)
Affinity DataIC50:  4.37E+3nMAssay Description:Inhibition of phosphorylation of c-Met in human MKN45 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Chemrf Laboratories

Curated by ChEMBL
LigandPNGBDBM50317323(CHEMBL1094718 | N-(3-fluoro-4-(2-(1-methyl-1H-imid...)
Affinity DataIC50:  6.87E+3nMAssay Description:Inhibition of phosphorylation of c-Met in human MKN45 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed