Found 60 Enz. Inhib. hit(s) with all data for entry = 50045830 
Affinity DataIC50: 23nMAssay Description:Inhibition human HPGDS expressed in Escherichia coli assessed as reduction in GST enzymatic activity using MCBL and glutathione incubated for 30 mins...More data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataIC50: 26nMAssay Description:Inhibition human HPGDS expressed in Escherichia coli assessed as reduction in GST enzymatic activity using MCBL and glutathione incubated for 30 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Inhibition human HPGDS expressed in Escherichia coli assessed as reduction in GST enzymatic activity using MCBL and glutathione incubated for 30 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition human HPGDS expressed in Escherichia coli assessed as reduction in GST enzymatic activity using MCBL and glutathione incubated for 30 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Inhibition human HPGDS expressed in Escherichia coli assessed as reduction in GST enzymatic activity using MCBL and glutathione incubated for 30 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 43nMAssay Description:Inhibition human HPGDS expressed in Escherichia coli assessed as reduction in GST enzymatic activity using MCBL and glutathione incubated for 30 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 48nMAssay Description:Inhibition human HPGDS expressed in Escherichia coli assessed as reduction in GST enzymatic activity using MCBL and glutathione incubated for 30 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition human HPGDS expressed in Escherichia coli assessed as reduction in GST enzymatic activity using MCBL and glutathione incubated for 30 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition human HPGDS expressed in Escherichia coli assessed as reduction in GST enzymatic activity using MCBL and glutathione incubated for 30 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition human HPGDS expressed in Escherichia coli assessed as reduction in GST enzymatic activity using MCBL and glutathione incubated for 30 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 71nMAssay Description:Inhibition human HPGDS expressed in Escherichia coli assessed as reduction in GST enzymatic activity using MCBL and glutathione incubated for 30 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Inhibition human HPGDS expressed in Escherichia coli assessed as reduction in GST enzymatic activity using MCBL and glutathione incubated for 30 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Inhibition human HPGDS expressed in Escherichia coli assessed as reduction in GST enzymatic activity using MCBL and glutathione incubated for 30 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:Inhibition human HPGDS expressed in Escherichia coli assessed as reduction in GST enzymatic activity using MCBL and glutathione incubated for 30 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition human HPGDS expressed in Escherichia coli assessed as reduction in GST enzymatic activity using MCBL and glutathione incubated for 30 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 210nMAssay Description:Inhibition fluorescein-conjugated ligand binding to human HPGDS expressed in Escherichia coli by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 230nMAssay Description:Inhibition human HPGDS expressed in Escherichia coli assessed as reduction in GST enzymatic activity using MCBL and glutathione incubated for 30 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition human HPGDS expressed in Escherichia coli assessed as reduction in GST enzymatic activity using MCBL and glutathione incubated for 30 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 320nMAssay Description:Inhibition human HPGDS expressed in Escherichia coli assessed as reduction in GST enzymatic activity using MCBL and glutathione incubated for 30 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 460nMAssay Description:Inhibition fluorescein-conjugated ligand binding to human HPGDS expressed in Escherichia coli by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 590nMAssay Description:Inhibition human HPGDS expressed in Escherichia coli assessed as reduction in GST enzymatic activity using MCBL and glutathione incubated for 30 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 820nMAssay Description:Inhibition fluorescein-conjugated ligand binding to human HPGDS expressed in Escherichia coli by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition human HPGDS expressed in Escherichia coli assessed as reduction in GST enzymatic activity using MCBL and glutathione incubated for 30 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition fluorescein-conjugated ligand binding to human HPGDS expressed in Escherichia coli by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKd: 20nMAssay Description:Binding affinity to human HPGDS expressed in Escherichia coli by isothermal titration calorimetryMore data for this Ligand-Target Pair
Affinity DataKd: 50nMAssay Description:Binding affinity to human HPGDS expressed in Escherichia coli using 1-phenylpyrazole-4-carboxylic acid/6-(3-fluorophenyl)pyridine-3-carboxamide as re...More data for this Ligand-Target Pair
Affinity DataKd: 60nMAssay Description:Binding affinity to human HPGDS expressed in Escherichia coli using 1-phenylpyrazole-4-carboxylic acid/6-(3-fluorophenyl)pyridine-3-carboxamide as re...More data for this Ligand-Target Pair
Affinity DataKd: 300nMAssay Description:Binding affinity to human HPGDS expressed in Escherichia coli using 1-phenylpyrazole-4-carboxylic acid/6-(3-fluorophenyl)pyridine-3-carboxamide as re...More data for this Ligand-Target Pair
Affinity DataKd: 200nMAssay Description:Binding affinity to human HPGDS expressed in Escherichia coli using 1-phenylpyrazole-4-carboxylic acid/6-(3-fluorophenyl)pyridine-3-carboxamide as re...More data for this Ligand-Target Pair
Affinity DataKd: 1.00E+3nMAssay Description:Binding affinity to human HPGDS expressed in Escherichia coli using 1-phenylpyrazole-4-carboxylic acid/6-(3-fluorophenyl)pyridine-3-carboxamide as re...More data for this Ligand-Target Pair
Affinity DataKd: <2.00E+4nMAssay Description:Binding affinity to human HPGDS expressed in Escherichia coli using 1-phenylpyrazole-4-carboxylic acid/6-(3-fluorophenyl)pyridine-3-carboxamide as re...More data for this Ligand-Target Pair
Affinity DataKd: 60nMAssay Description:Binding affinity to human HPGDS expressed in Escherichia coli using 1-phenylpyrazole-4-carboxylic acid/6-(3-fluorophenyl)pyridine-3-carboxamide as re...More data for this Ligand-Target Pair
Affinity DataKd: <100nMAssay Description:Binding affinity to human HPGDS expressed in Escherichia coli using 1-phenylpyrazole-4-carboxylic acid/6-(3-fluorophenyl)pyridine-3-carboxamide as re...More data for this Ligand-Target Pair
Affinity DataKd: 200nMAssay Description:Binding affinity to human HPGDS expressed in Escherichia coli using 1-phenylpyrazole-4-carboxylic acid/6-(3-fluorophenyl)pyridine-3-carboxamide as re...More data for this Ligand-Target Pair
Affinity DataKd: 1.40E+4nMAssay Description:Binding affinity to human HPGDS expressed in Escherichia coli using 1-phenylpyrazole-4-carboxylic acid/6-(3-fluorophenyl)pyridine-3-carboxamide as re...More data for this Ligand-Target Pair
Affinity DataKd: 400nMAssay Description:Binding affinity to human HPGDS expressed in Escherichia coli using 1-phenylpyrazole-4-carboxylic acid/6-(3-fluorophenyl)pyridine-3-carboxamide as re...More data for this Ligand-Target Pair
Affinity DataKd: 1.30E+4nMAssay Description:Binding affinity to human HPGDS expressed in Escherichia coli using 1-phenylpyrazole-4-carboxylic acid/6-(3-fluorophenyl)pyridine-3-carboxamide as re...More data for this Ligand-Target Pair
Affinity DataKd: 1.00E+3nMAssay Description:Binding affinity to human HPGDS expressed in Escherichia coli using 1-phenylpyrazole-4-carboxylic acid/6-(3-fluorophenyl)pyridine-3-carboxamide as re...More data for this Ligand-Target Pair
Affinity DataKd: 200nMAssay Description:Binding affinity to human HPGDS expressed in Escherichia coli using 1-phenylpyrazole-4-carboxylic acid/6-(3-fluorophenyl)pyridine-3-carboxamide as re...More data for this Ligand-Target Pair
Affinity DataKd: 2.00E+3nMAssay Description:Binding affinity to human HPGDS expressed in Escherichia coli using 1-phenylpyrazole-4-carboxylic acid/6-(3-fluorophenyl)pyridine-3-carboxamide as re...More data for this Ligand-Target Pair
Affinity DataKd: 400nMAssay Description:Binding affinity to human HPGDS expressed in Escherichia coli using 1-phenylpyrazole-4-carboxylic acid/6-(3-fluorophenyl)pyridine-3-carboxamide as re...More data for this Ligand-Target Pair
Affinity DataKd: 1.00E+4nMAssay Description:Binding affinity to human HPGDS expressed in Escherichia coli using 1-phenylpyrazole-4-carboxylic acid/6-(3-fluorophenyl)pyridine-3-carboxamide as re...More data for this Ligand-Target Pair
Affinity DataKd: 1.40E+5nMAssay Description:Binding affinity to human HPGDS expressed in Escherichia coli by isothermal titration calorimetryMore data for this Ligand-Target Pair
Affinity DataKd: 800nMAssay Description:Binding affinity to human HPGDS expressed in Escherichia coli by isothermal titration calorimetryMore data for this Ligand-Target Pair
Affinity DataKd: 12nMAssay Description:Binding affinity to human HPGDS expressed in Escherichia coli by isothermal titration calorimetryMore data for this Ligand-Target Pair
Affinity DataKd: 35nMAssay Description:Binding affinity to human HPGDS expressed in Escherichia coli by isothermal titration calorimetryMore data for this Ligand-Target Pair
Affinity DataKd: 300nMAssay Description:Binding affinity to human HPGDS expressed in Escherichia coli by isothermal titration calorimetryMore data for this Ligand-Target Pair
Affinity DataKd: 210nMAssay Description:Binding affinity to human HPGDS expressed in Escherichia coli by isothermal titration calorimetryMore data for this Ligand-Target Pair
Affinity DataEC50: 35nMAssay Description:Inhibition HPGDS in human MEG01 cells assessed as reduction in PGD2 production incubated for 30 mins followed by stimulation with 5 uM ionomycin for ...More data for this Ligand-Target Pair
Affinity DataEC50: 130nMAssay Description:Inhibition HPGDS in human MEG01 cells assessed as reduction in PGD2 production incubated for 30 mins followed by stimulation with 5 uM ionomycin for ...More data for this Ligand-Target Pair
