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Target
Cholecystokinin receptor type A
Ligand
BDBM50041650
Substrate
n/a
Meas. Tech.
ChEMBL_49582 (CHEMBL661235)
IC50
16±n/a nM
Citation
 Elliott, RL; Kopecka, H; Tufano, MD; Shue, YK; Gauri, AJ; Lin, CW; Bianchi, BR; Miller, TR; Witte, DG; Stashko, MA Novel Asp32-replacement tetrapeptide analogues as potent and selective CCK-A agonists. J Med Chem 37:1562-8 (1994) [PubMed]  Article 
Target
Name:
Cholecystokinin receptor type A
Synonyms:
CCK-A receptor | CCK-AR | CCK1-R | CCKAR | CCKAR_CAVPO | Cholecystokinin A receptor | Cholecystokinin receptor type A | Cholecystokinin-1 receptor
Type:
n/a
Mol. Mass.:
48229.77
Organism:
Cavia porcellus
Description:
n/a
Residue:
430
Sequence:
MDVVDSLFVNGSNITSACELGFENETLFCLDRPRPSKEWQPAVQILLYSLIFLLSVLGNTLVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPSLLKDFIFGSAVCKTTTYFMGTSVSVSTFNLVAISLERYGAICKPLQSRVWQTKSHALKVIAATWCLSFTIMTPYPIYSNLVPFTKNNNQTGNMCRFLLPNDVMQQTWHTFLLLILFLIPGIVMMVAYGLISLELYQGIKFDAIQKKSAKERKTSTGSSGPMEDSDGCYLQKSRHPRKLELRQLSPSSSGSNRINRIRSSSSTANLMAKKRVIRMLIVIVVLFFLCWMPIFSANAWRAYDTVSAERHLSGTPISFILLLSYTSSCVNPIIYCFMNKRFRLGFMATFPCCPNPGTPGVRGEMGEEEEGRTTGASLSRYSYSHMSTSAPPP
  
Inhibitor
Name:
BDBM50041650
Synonyms:
CHEMBL39310 | [1-[(S)-1-[(R)-1-((S)-1-Carbamoyl-2-phenyl-ethyl)-5-oxo-pyrrolidin-3-ylcarbamoyl]-5-(3-o-tolyl-ureido)-pentylcarbamoyl]-2-(1H-indol-3-yl)-ethyl]-carbamic acid tert-butyl ester
Type:
Small organic molecule
Emp. Form.:
C43H54N8O7
Mol. Mass.:
794.9383
SMILES:
Cc1ccccc1NC(=O)NCCCC[C@H](NC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)OC(C)(C)C)C(=O)N[C@H]1CN([C@@H](Cc2ccccc2)C(N)=O)C(=O)C1
Structure:
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