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Target
Sigma non-opioid intracellular receptor 1
Ligand
BDBM50109390
Substrate
n/a
Meas. Tech.
ChEBML_201564
Ki
14±n/a nM
Citation
 Maeda, DY; Williams, W; Kim, WE; Thatcher, LN; Bowen, WD; Coop, A N-arylalkylpiperidines as high-affinity sigma-1 and sigma-2 receptor ligands: phenylpropylamines as potential leads for selective sigma-2 agents. Bioorg Med Chem Lett 12:497-500 (2002) [PubMed]  Article 
Target
Name:
Sigma non-opioid intracellular receptor 1
Synonyms:
Opioid receptor | Oprs1 | SGMR1_RAT | Sigma | Sigma non-opioid intracellular receptor 1 | Sigma opioid receptor | Sigma-1 | Sigmar1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
25266.54
Organism:
RAT
Description:
Q9R0C9
Residue:
223
Sequence:
MPWAVGRRWAWITLFLTIVAVLIQAVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSRLIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSHGHSGRYWAEISDTIISGTFHQWREGTTKSEVYYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPSTLAFALSDTIFSTQDFLTLFYTLRAYARGLRLELTTYLFGQDP
  
Inhibitor
Name:
BDBM50109390
Synonyms:
2-(3-Phenyl-propyl)-1,2,3,4-tetrahydro-isoquinoline | CHEMBL145921
Type:
Small organic molecule
Emp. Form.:
C18H21N
Mol. Mass.:
251.366
SMILES:
C(CN1CCc2ccccc2C1)Cc1ccccc1
Structure:
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