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Target
Glucagon-like peptide 1 receptor
Ligand
BDBM50301949
Substrate
n/a
Meas. Tech.
ChEMBL_598670 (CHEMBL1048996)
EC50
0.034000±n/a nM
Citation
 Mapelli, C; Natarajan, SI; Meyer, JP; Bastos, MM; Bernatowicz, MS; Lee, VG; Pluscec, J; Riexinger, DJ; Sieber-McMaster, ES; Constantine, KL; Smith-Monroy, CA; Golla, R; Ma, Z; Longhi, DA; Shi, D; Xin, L; Taylor, JR; Koplowitz, B; Chi, CL; Khanna, A; Robinson, GW; Seethala, R; Antal-Zimanyi, IA; Stoffel, RH; Han, S; Whaley, JM; Huang, CS; Krupinski, J; Ewing, WR Eleven amino acid glucagon-like peptide-1 receptor agonists with antidiabetic activity. J Med Chem 52:7788-99 (2009) [PubMed]  Article 
Target
Name:
Glucagon-like peptide 1 receptor
Synonyms:
GLP-1 receptor | GLP-1-R | GLP-1R | GLP1R | GLP1R_HUMAN | Glucagon-like peptide 1 receptor | Glucagon-like peptide 1 receptor (GLP-1)
Type:
Enzyme
Mol. Mass.:
53035.78
Organism:
Homo sapiens (Human)
Description:
P43220
Residue:
463
Sequence:
MAGAPGPLRLALLLLGMVGRAGPRPQGATVSLWETVQKWREYRRQCQRSLTEDPPPATDLFCNRTFDEYACWPDGEPGSFVNVSCPWYLPWASSVPQGHVYRFCTAEGLWLQKDNSSLPWRDLSECEESKRGERSSPEEQLLFLYIIYTVGYALSFSALVIASAILLGFRHLHCTRNYIHLNLFASFILRALSVFIKDAALKWMYSTAAQQHQWDGLLSYQDSLSCRLVFLLMQYCVAANYYWLLVEGVYLYTLLAFSVLSEQWIFRLYVSIGWGVPLLFVVPWGIVKYLYEDEGCWTRNSNMNYWLIIRLPILFAIGVNFLIFVRVICIVVSKLKANLMCKTDIKCRLAKSTLTLIPLLGTHEVIFAFVMDEHARGTLRFIKLFTELSFTSFQGLMVAILYCFVNNEVQLEFRKSWERWRLEHLHIQRDSSMKPLKCPTSSLSSGATAGSSMYTATCQASCS
  
Inhibitor
Name:
BDBM50301949
Synonyms:
CHEMBL583264
Type:
Small organic molecule
Emp. Form.:
C144H224N40O45
Mol. Mass.:
3235.5604
SMILES:
n/a
Structure:
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