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TargetHypoxanthine phosphoribosyltransferase(Plasmodium vivax)
The University of Queensland

US Patent
LigandChemical structure of BindingDB Monomer ID 194499BDBM194499(BDBM50392265 | US9200020, Table 3 compound 8)
Affinity DataKi:  50nMpH: 7.4Assay Description:The Ki values were determined using a spectrophotometric assay at 25° C., 0.1 M Tris-HCl, 10 mM MgCl2, pH 7.4 (Keough, D. T.; Ng, A. L.; Winzor, D. J...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2016
Entry Details
US Patent

TargetHypoxanthine phosphoribosyltransferase(Plasmodium vivax)
The University of Queensland

US Patent
LigandChemical structure of BindingDB Monomer ID 194496BDBM194496(BDBM50392261 | US9200020, Table 3 compound 5)
Affinity DataKi:  300nMpH: 7.4Assay Description:The Ki values were determined using a spectrophotometric assay at 25° C., 0.1 M Tris-HCl, 10 mM MgCl2, pH 7.4 (Keough, D. T.; Ng, A. L.; Winzor, D. J...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2016
Entry Details
US Patent

TargetHypoxanthine phosphoribosyltransferase(Plasmodium vivax)
The University of Queensland

US Patent
LigandChemical structure of BindingDB Monomer ID 60890BDBM60890(BDBM50392251 | US9200020, Table 3 compound 5B)
Affinity DataKi:  700nM ΔG°:  -36.5kJ/moleT: 2°CAssay Description:The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitro ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2016
Entry Details
US Patent

TargetHypoxanthine phosphoribosyltransferase(Plasmodium vivax)
The University of Queensland

US Patent
LigandChemical structure of BindingDB Monomer ID 194502BDBM194502(US9200020, Table 3 compound 11 | BDBM50392267)
Affinity DataKi:  900nMpH: 7.4Assay Description:The Ki values were determined using a spectrophotometric assay at 25° C., 0.1 M Tris-HCl, 10 mM MgCl2, pH 7.4 (Keough, D. T.; Ng, A. L.; Winzor, D. J...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2016
Entry Details
US Patent

TargetHypoxanthine phosphoribosyltransferase(Plasmodium vivax)
The University of Queensland

US Patent
LigandChemical structure of BindingDB Monomer ID 194501BDBM194501(BDBM50392263 | US9200020, Table 3 compound 10)
Affinity DataKi:  1.40E+3nMpH: 7.4Assay Description:The Ki values were determined using a spectrophotometric assay at 25° C., 0.1 M Tris-HCl, 10 mM MgCl2, pH 7.4 (Keough, D. T.; Ng, A. L.; Winzor, D. J...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2016
Entry Details
US Patent

TargetHypoxanthine phosphoribosyltransferase(Plasmodium vivax)
The University of Queensland

US Patent
LigandChemical structure of BindingDB Monomer ID 194492BDBM194492(US9200020, Table 3 compound 1 | BDBM50392258)
Affinity DataKi:  1.50E+3nMpH: 7.4Assay Description:The Ki values were determined using a spectrophotometric assay at 25° C., 0.1 M Tris-HCl, 10 mM MgCl2, pH 7.4 (Keough, D. T.; Ng, A. L.; Winzor, D. J...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2016
Entry Details
US Patent

TargetHypoxanthine phosphoribosyltransferase(Plasmodium vivax)
The University of Queensland

US Patent
LigandChemical structure of BindingDB Monomer ID 60894BDBM60894(BDBM50392256 | US9200020, Table 3 compound 9B)
Affinity DataKi:  1.60E+3nM ΔG°:  -34.4kJ/moleT: 2°CAssay Description:The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitro ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2016
Entry Details
US Patent

TargetHypoxanthine phosphoribosyltransferase(Plasmodium vivax)
The University of Queensland

US Patent
LigandChemical structure of BindingDB Monomer ID 194493BDBM194493(US9200020, Table 3 compound 2 | BDBM50392259)
Affinity DataKi:  4.00E+3nMpH: 7.4Assay Description:The Ki values were determined using a spectrophotometric assay at 25° C., 0.1 M Tris-HCl, 10 mM MgCl2, pH 7.4 (Keough, D. T.; Ng, A. L.; Winzor, D. J...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2016
Entry Details
US Patent

TargetHypoxanthine phosphoribosyltransferase(Plasmodium vivax)
The University of Queensland

US Patent
LigandChemical structure of BindingDB Monomer ID 194497BDBM194497(BDBM50392262 | US9200020, Table 3 compound 6)
Affinity DataKi:  8.00E+3nMpH: 7.4Assay Description:The Ki values were determined using a spectrophotometric assay at 25° C., 0.1 M Tris-HCl, 10 mM MgCl2, pH 7.4 (Keough, D. T.; Ng, A. L.; Winzor, D. J...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2016
Entry Details
US Patent

TargetHypoxanthine phosphoribosyltransferase(Plasmodium vivax)
The University of Queensland

US Patent
LigandChemical structure of BindingDB Monomer ID 194491BDBM194491(US9200020, Table 1, Compound 2 | BDBM50392245)
Affinity DataKi:  1.10E+4nMpH: 7.4Assay Description:The Ki values were determined using a spectrophotometric assay at 25° C., 0.1 M Tris-HCl, 10 mM MgCl2, pH 7.4 (Keough, D. T.; Ng, A. L.; Winzor, D. J...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2016
Entry Details
US Patent

TargetHypoxanthine phosphoribosyltransferase(Plasmodium vivax)
The University of Queensland

US Patent
LigandChemical structure of BindingDB Monomer ID 60886BDBM60886(US9200020, Table 3, Compound 1B | BDBM50392247)
Affinity DataKi:  1.10E+4nM ΔG°:  -29.4kJ/moleT: 2°CAssay Description:The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitro ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2016
Entry Details
US Patent

TargetHypoxanthine phosphoribosyltransferase(Plasmodium vivax)
The University of Queensland

US Patent
LigandChemical structure of BindingDB Monomer ID 60897BDBM60897(US9200020, Table 3 compound 11B | BDBM50392257)
Affinity DataKi:  1.30E+4nM ΔG°:  -29.0kJ/moleT: 2°CAssay Description:The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitro ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2016
Entry Details
US Patent

TargetHypoxanthine phosphoribosyltransferase(Plasmodium vivax)
The University of Queensland

US Patent
LigandChemical structure of BindingDB Monomer ID 60896BDBM60896(BDBM50392253 | US9200020, Table 3 compound 10B)
Affinity DataKi:  2.10E+4nM ΔG°:  -27.8kJ/moleT: 2°CAssay Description:The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitro ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2016
Entry Details
US Patent

TargetHypoxanthine phosphoribosyltransferase(Plasmodium vivax)
The University of Queensland

US Patent
LigandChemical structure of BindingDB Monomer ID 60887BDBM60887(US9200020, Table 3, Compound 2B | BDBM50392248)
Affinity DataKi:  2.10E+4nM ΔG°:  -27.8kJ/moleT: 2°CAssay Description:The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitro ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2016
Entry Details
US Patent

TargetHypoxanthine phosphoribosyltransferase(Plasmodium vivax)
The University of Queensland

US Patent
LigandChemical structure of BindingDB Monomer ID 194500BDBM194500(BDBM50392266 | US9200020, Table 3 compound 9)
Affinity DataKi:  2.50E+4nMpH: 7.4Assay Description:The Ki values were determined using a spectrophotometric assay at 25° C., 0.1 M Tris-HCl, 10 mM MgCl2, pH 7.4 (Keough, D. T.; Ng, A. L.; Winzor, D. J...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2016
Entry Details
US Patent

TargetHypoxanthine phosphoribosyltransferase(Plasmodium vivax)
The University of Queensland

US Patent
LigandChemical structure of BindingDB Monomer ID 194498BDBM194498(BDBM50392264 | US9200020, Table 3 compound 7)
Affinity DataKi:  2.80E+4nMpH: 7.4Assay Description:The Ki values were determined using a spectrophotometric assay at 25° C., 0.1 M Tris-HCl, 10 mM MgCl2, pH 7.4 (Keough, D. T.; Ng, A. L.; Winzor, D. J...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2016
Entry Details
US Patent

TargetHypoxanthine phosphoribosyltransferase(Plasmodium vivax)
The University of Queensland

US Patent
LigandChemical structure of BindingDB Monomer ID 60893BDBM60893(US9200020, Table 3 compound 8B)
Affinity DataKi:  4.10E+4nM ΔG°:  -26.0kJ/moleT: 2°CAssay Description:The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitro ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2016
Entry Details
US Patent

TargetHypoxanthine phosphoribosyltransferase(Plasmodium vivax)
The University of Queensland

US Patent
LigandChemical structure of BindingDB Monomer ID 194495BDBM194495(BDBM50392250 | US9200020, Table 3 compound 4)
Affinity DataKi:  4.70E+4nM ΔG°:  -25.7kJ/moleT: 2°CAssay Description:The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitro ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2016
Entry Details
US Patent

TargetHypoxanthine phosphoribosyltransferase(Plasmodium vivax)
The University of Queensland

US Patent
LigandChemical structure of BindingDB Monomer ID 60892BDBM60892(BDBM50392254 | US9200020, Table 3 compound 7B)
Affinity DataKi:  1.78E+5nM ΔG°:  -22.3kJ/moleT: 2°CAssay Description:The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitro ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2016
Entry Details
US Patent

TargetHypoxanthine phosphoribosyltransferase(Plasmodium vivax)
The University of Queensland

US Patent
LigandChemical structure of BindingDB Monomer ID 194494BDBM194494(BDBM50392260 | US9200020, Table 3 compound 3)
Affinity DataKi: >2.00E+5nMpH: 7.4Assay Description:The Ki values were determined using a spectrophotometric assay at 25° C., 0.1 M Tris-HCl, 10 mM MgCl2, pH 7.4 (Keough, D. T.; Ng, A. L.; Winzor, D. J...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2016
Entry Details
US Patent

TargetHypoxanthine phosphoribosyltransferase(Plasmodium vivax)
The University of Queensland

US Patent
LigandChemical structure of BindingDB Monomer ID 60891BDBM60891(BDBM50392252 | US9200020, Table 3 compound 6B)
Affinity DataKi: >2.30E+5nM ΔG°: >-21.6kJ/moleT: 2°CAssay Description:The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitro ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2016
Entry Details
US Patent

TargetHypoxanthine phosphoribosyltransferase(Plasmodium vivax)
The University of Queensland

US Patent
LigandChemical structure of BindingDB Monomer ID 60888BDBM60888(US9200020, Table 3, Compound 3B | BDBM50392249)
Affinity DataKi: >2.50E+5nM ΔG°: >-21.4kJ/moleT: 2°CAssay Description:The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitro ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2016
Entry Details
US Patent

TargetHypoxanthine phosphoribosyltransferase(Plasmodium vivax)
The University of Queensland

US Patent
LigandChemical structure of BindingDB Monomer ID 60884BDBM60884(US9200020, Table 1, Compound 2B)
Affinity DataKi: >2.50E+5nM ΔG°: >-21.4kJ/moleT: 2°CAssay Description:The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitro ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/27/2016
Entry Details
US Patent