Compile Data Set for Download or QSAR
Report error Found 309 of affinity data for UniProtKB/TrEMBL: O95352
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 475984BDBM475984({(2R,3S,4R,5R)-5-[4-amino-3-(methylsulfanyl)-1H-py...)
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 475978BDBM475978({(2R,3S,4R,5R)-5-[4-amino-3-(1H-pyrazol-4-ylsulfan...)
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 476001BDBM476001({(2R,3S,4R,5R)-5-[4-amino-3-(isopropylsulfanyl)-1H...)
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 476012BDBM476012([(2R,3S,4R,5R)-5-{4-amino-3-[(3-methylphenyl)sulfa...)
Affinity DataIC50: 18nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 475984BDBM475984({(2R,3S,4R,5R)-5-[4-amino-3-(methylsulfanyl)-1H-py...)
Affinity DataIC50: 20nMAssay Description:The total volume of the ATG7 enzymatic assay is 50 μL and contains 50 mM HEPES Hemisodium (pH 7.5), 0.05% BSA, 0.01% Tween-20, 25 mM NaCl, 5 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2021
Entry Details
US Patent

TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 475982BDBM475982([(2R,3S,4R,5R)-5-{4-amino-3-[(3-chlorophenyl)sulfa...)
Affinity DataIC50: 20nMAssay Description:The total volume of the ATG7 enzymatic assay is 50 μL and contains 50 mM HEPES Hemisodium (pH 7.5), 0.05% BSA, 0.01% Tween-20, 25 mM NaCl, 5 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2021
Entry Details
US Patent

TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 476046BDBM476046({(2R,3R,4S,5R)-5-[4-amino-3-(cyclopentylsulfanyl)-...)
Affinity DataIC50: 20nMAssay Description:The total volume of the ATG7 enzymatic assay is 50 μL and contains 50 mM HEPES Hemisodium (pH 7.5), 0.05% BSA, 0.01% Tween-20, 25 mM NaCl, 5 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2021
Entry Details
US Patent

TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 476012BDBM476012([(2R,3S,4R,5R)-5-{4-amino-3-[(3-methylphenyl)sulfa...)
Affinity DataIC50: 20nMAssay Description:The total volume of the ATG7 enzymatic assay is 50 μL and contains 50 mM HEPES Hemisodium (pH 7.5), 0.05% BSA, 0.01% Tween-20, 25 mM NaCl, 5 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2021
Entry Details
US Patent

TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 475978BDBM475978({(2R,3S,4R,5R)-5-[4-amino-3-(1H-pyrazol-4-ylsulfan...)
Affinity DataIC50: 20nMAssay Description:The total volume of the ATG7 enzymatic assay is 50 μL and contains 50 mM HEPES Hemisodium (pH 7.5), 0.05% BSA, 0.01% Tween-20, 25 mM NaCl, 5 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2021
Entry Details
US Patent

TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 476008BDBM476008({(2R,3S,4R,5R)-5-[4-amino-3-(cyclopropylsulfanyl)-...)
Affinity DataIC50: 20nMAssay Description:The total volume of the ATG7 enzymatic assay is 50 μL and contains 50 mM HEPES Hemisodium (pH 7.5), 0.05% BSA, 0.01% Tween-20, 25 mM NaCl, 5 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2021
Entry Details
US Patent

TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 476005BDBM476005({(2R,3S,4R,5R)-5-[4-amino-3-(cyclopentylsulfanyl)-...)
Affinity DataIC50: 20nMAssay Description:The total volume of the ATG7 enzymatic assay is 50 μL and contains 50 mM HEPES Hemisodium (pH 7.5), 0.05% BSA, 0.01% Tween-20, 25 mM NaCl, 5 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2021
Entry Details
US Patent

TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 476001BDBM476001({(2R,3S,4R,5R)-5-[4-amino-3-(isopropylsulfanyl)-1H...)
Affinity DataIC50: 20nMAssay Description:The total volume of the ATG7 enzymatic assay is 50 μL and contains 50 mM HEPES Hemisodium (pH 7.5), 0.05% BSA, 0.01% Tween-20, 25 mM NaCl, 5 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2021
Entry Details
US Patent

TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 476084BDBM476084({(2R,3R,4S,5R)-5-[4-amino-3-(isopropylsulfanyl)-1H...)
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 476097BDBM476097([(2R,3R,4S,5R)-5-{4-amino-3-[(5-methylpyridin-2-yl...)
Affinity DataIC50: 20nMAssay Description:The total volume of the ATG7 enzymatic assay is 50 μL and contains 50 mM HEPES Hemisodium (pH 7.5), 0.05% BSA, 0.01% Tween-20, 25 mM NaCl, 5 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2021
Entry Details
US Patent

TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 476032BDBM476032([(2R,3S,4R,5R)-5-{4-amino-3-[(4-methylphenyl)sulfa...)
Affinity DataIC50: 20nMAssay Description:The total volume of the ATG7 enzymatic assay is 50 μL and contains 50 mM HEPES Hemisodium (pH 7.5), 0.05% BSA, 0.01% Tween-20, 25 mM NaCl, 5 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2021
Entry Details
US Patent

TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 475999BDBM475999({(2R,3S,4R,5R)-5-[4-amino-3-(cyclobutylsulfanyl)-1...)
Affinity DataIC50: 20nMAssay Description:The total volume of the ATG7 enzymatic assay is 50 μL and contains 50 mM HEPES Hemisodium (pH 7.5), 0.05% BSA, 0.01% Tween-20, 25 mM NaCl, 5 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2021
Entry Details
US Patent

TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 476061BDBM476061({(2R,3R,4S,5R)-5-[4-amino-3-(tert-butylsulfanyl)-1...)
Affinity DataIC50: 20nMAssay Description:The total volume of the ATG7 enzymatic assay is 50 μL and contains 50 mM HEPES Hemisodium (pH 7.5), 0.05% BSA, 0.01% Tween-20, 25 mM NaCl, 5 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2021
Entry Details
US Patent

TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 476093BDBM476093([(2R,3R,4S,5R)-5-{4-amino-3-[(cyclobutylmethyl)sul...)
Affinity DataIC50: 20nMAssay Description:The total volume of the ATG7 enzymatic assay is 50 μL and contains 50 mM HEPES Hemisodium (pH 7.5), 0.05% BSA, 0.01% Tween-20, 25 mM NaCl, 5 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2021
Entry Details
US Patent

TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 476092BDBM476092({(2R,3R,4S,5R)-5-[4-amino-3-(cyclobutylsulfanyl)-1...)
Affinity DataIC50: 20nMAssay Description:The total volume of the ATG7 enzymatic assay is 50 μL and contains 50 mM HEPES Hemisodium (pH 7.5), 0.05% BSA, 0.01% Tween-20, 25 mM NaCl, 5 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2021
Entry Details
US Patent

TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 476057BDBM476057([(2R,3R,4S,5R)-5-{4-amino-3-[(4-methylpyridin-2-yl...)
Affinity DataIC50: 20nMAssay Description:The total volume of the ATG7 enzymatic assay is 50 μL and contains 50 mM HEPES Hemisodium (pH 7.5), 0.05% BSA, 0.01% Tween-20, 25 mM NaCl, 5 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2021
Entry Details
US Patent

TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 475992BDBM475992([(2R,3S,4R,5R)-5-{4-amino-3-[(cyclopropylmethyl)su...)
Affinity DataIC50: 20nMAssay Description:The total volume of the ATG7 enzymatic assay is 50 μL and contains 50 mM HEPES Hemisodium (pH 7.5), 0.05% BSA, 0.01% Tween-20, 25 mM NaCl, 5 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2021
Entry Details
US Patent

TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 476056BDBM476056({(2R,3R,4S,5R)-5-[4-amino-3-(pyridin-2-ylsulfanyl)...)
Affinity DataIC50: 20nMAssay Description:The total volume of the ATG7 enzymatic assay is 50 μL and contains 50 mM HEPES Hemisodium (pH 7.5), 0.05% BSA, 0.01% Tween-20, 25 mM NaCl, 5 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2021
Entry Details
US Patent

TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 476022BDBM476022([(2R,3S,4R,5R)-5-(4-amino-3-iodo-1H-pyrazolo[3,4-d...)
Affinity DataIC50: 20nMAssay Description:The total volume of the ATG7 enzymatic assay is 50 μL and contains 50 mM HEPES Hemisodium (pH 7.5), 0.05% BSA, 0.01% Tween-20, 25 mM NaCl, 5 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2021
Entry Details
US Patent

TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 475988BDBM475988([(2R,3S,4R,5R)-5-{4-amino-3-[(2-hydroxyethyl)sulfa...)
Affinity DataIC50: 20nMAssay Description:The total volume of the ATG7 enzymatic assay is 50 μL and contains 50 mM HEPES Hemisodium (pH 7.5), 0.05% BSA, 0.01% Tween-20, 25 mM NaCl, 5 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2021
Entry Details
US Patent

TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 475993BDBM475993({(2R,3S,4R,5R)-5-[4-amino-3-(ethylsulfanyl)-1H-pyr...)
Affinity DataIC50: 22nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 475994BDBM475994({(2R,3S,4R,5R)-5-[4-amino-3-(benzylsulfanyl)-1H-py...)
Affinity DataIC50: 23nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 476126BDBM476126({(2R,3S,5R)-5-[4-amino-3-(isopropylsulfanyl)-1H-py...)
Affinity DataIC50: 27nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 476025BDBM476025({(2R,3S,4R,5R)-5-[4-amino-3-(phenylsulfanyl)-1H-py...)
Affinity DataIC50: 29nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 475969BDBM475969({(2R,3S,4R,5R)-5-[4-amino-3-(difluoromethoxy)-1H-p...)
Affinity DataIC50: 29nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 476049BDBM476049([(2R,3R,4S,5R)-5-{4-amino-3-[(3-chlorophenyl)sulfa...)
Affinity DataIC50: 31nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 475983BDBM475983([(2R,3S,4R,5R)-5-{4-amino-3-[(4-methylbenzyl)sulfa...)
Affinity DataIC50: 35nMAssay Description:The total volume of the ATG7 enzymatic assay is 50 μL and contains 50 mM HEPES Hemisodium (pH 7.5), 0.05% BSA, 0.01% Tween-20, 25 mM NaCl, 5 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2021
Entry Details
US Patent

TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 475981BDBM475981([(2R,3S,4R,5R)-5-{4-amino-3-[(2-methylbenzyl)sulfa...)
Affinity DataIC50: 35nMAssay Description:The total volume of the ATG7 enzymatic assay is 50 μL and contains 50 mM HEPES Hemisodium (pH 7.5), 0.05% BSA, 0.01% Tween-20, 25 mM NaCl, 5 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2021
Entry Details
US Patent

TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 475980BDBM475980([(2R,3S,4R,5R)-5-{4-amino-3-[(4-methoxybenzyl)sulf...)
Affinity DataIC50: 35nMAssay Description:The total volume of the ATG7 enzymatic assay is 50 μL and contains 50 mM HEPES Hemisodium (pH 7.5), 0.05% BSA, 0.01% Tween-20, 25 mM NaCl, 5 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2021
Entry Details
US Patent

TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 475977BDBM475977([(2R,3S,4R,5R)-5-{4-amino-3-[(2-methoxyethyl)sulfa...)
Affinity DataIC50: 35nMAssay Description:The total volume of the ATG7 enzymatic assay is 50 μL and contains 50 mM HEPES Hemisodium (pH 7.5), 0.05% BSA, 0.01% Tween-20, 25 mM NaCl, 5 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2021
Entry Details
US Patent

TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 475975BDBM475975([(2R,3S,4R,5R)-5-(4-amino-3-{[4-(trifluoromethyl)b...)
Affinity DataIC50: 35nMAssay Description:The total volume of the ATG7 enzymatic assay is 50 μL and contains 50 mM HEPES Hemisodium (pH 7.5), 0.05% BSA, 0.01% Tween-20, 25 mM NaCl, 5 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2021
Entry Details
US Patent

TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 475974BDBM475974([(2R,3S,4R,5R)-5-(4-amino-3-{[4-(trifluoromethoxy)...)
Affinity DataIC50: 35nMAssay Description:The total volume of the ATG7 enzymatic assay is 50 μL and contains 50 mM HEPES Hemisodium (pH 7.5), 0.05% BSA, 0.01% Tween-20, 25 mM NaCl, 5 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2021
Entry Details
US Patent

TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 476102BDBM476102([(2R,3R,4S,5R)-5-(4-amino-3-{[(1R)-1-cyclopropylet...)
Affinity DataIC50: 35nMAssay Description:The total volume of the ATG7 enzymatic assay is 50 μL and contains 50 mM HEPES Hemisodium (pH 7.5), 0.05% BSA, 0.01% Tween-20, 25 mM NaCl, 5 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2021
Entry Details
US Patent

TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 475973BDBM475973([(2R,3S,4R,5R)-5-{4-amino-3-[(3-methylbenzyl)sulfa...)
Affinity DataIC50: 35nMAssay Description:The total volume of the ATG7 enzymatic assay is 50 μL and contains 50 mM HEPES Hemisodium (pH 7.5), 0.05% BSA, 0.01% Tween-20, 25 mM NaCl, 5 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2021
Entry Details
US Patent

TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 476100BDBM476100({(2R,3R,4S,5R)-5-[4-amino-3-(benzylsulfanyl)-1H-py...)
Affinity DataIC50: 35nMAssay Description:The total volume of the ATG7 enzymatic assay is 50 μL and contains 50 mM HEPES Hemisodium (pH 7.5), 0.05% BSA, 0.01% Tween-20, 25 mM NaCl, 5 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2021
Entry Details
US Patent

TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 475969BDBM475969({(2R,3S,4R,5R)-5-[4-amino-3-(difluoromethoxy)-1H-p...)
Affinity DataIC50: 35nMAssay Description:The total volume of the ATG7 enzymatic assay is 50 μL and contains 50 mM HEPES Hemisodium (pH 7.5), 0.05% BSA, 0.01% Tween-20, 25 mM NaCl, 5 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2021
Entry Details
US Patent

TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 476086BDBM476086([(2R,3R,4S,5R)-5-{4-amino-3-[(3-methylphenyl)sulfa...)
Affinity DataIC50: 35nMAssay Description:Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 476126BDBM476126({(2R,3S,5R)-5-[4-amino-3-(isopropylsulfanyl)-1H-py...)
Affinity DataIC50: 35nMAssay Description:The total volume of the ATG7 enzymatic assay is 50 μL and contains 50 mM HEPES Hemisodium (pH 7.5), 0.05% BSA, 0.01% Tween-20, 25 mM NaCl, 5 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2021
Entry Details
US Patent

TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 475996BDBM475996([(2R,3S,4R,5R)-5-(4-amino-3-{[(1R,2R)-2-hydroxycyc...)
Affinity DataIC50: 35nMAssay Description:The total volume of the ATG7 enzymatic assay is 50 μL and contains 50 mM HEPES Hemisodium (pH 7.5), 0.05% BSA, 0.01% Tween-20, 25 mM NaCl, 5 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2021
Entry Details
US Patent

TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 475995BDBM475995({(2R,3S,4R,5R)-5-[4-amino-3-(tert-butylsulfanyl)-1...)
Affinity DataIC50: 35nMAssay Description:The total volume of the ATG7 enzymatic assay is 50 μL and contains 50 mM HEPES Hemisodium (pH 7.5), 0.05% BSA, 0.01% Tween-20, 25 mM NaCl, 5 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2021
Entry Details
US Patent

TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 476123BDBM476123([(2R,3S,5R)-5-{4-amino-3-[(2-fluoro-4-methoxypheny...)
Affinity DataIC50: 35nMAssay Description:The total volume of the ATG7 enzymatic assay is 50 μL and contains 50 mM HEPES Hemisodium (pH 7.5), 0.05% BSA, 0.01% Tween-20, 25 mM NaCl, 5 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2021
Entry Details
US Patent

TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 475994BDBM475994({(2R,3S,4R,5R)-5-[4-amino-3-(benzylsulfanyl)-1H-py...)
Affinity DataIC50: 35nMAssay Description:The total volume of the ATG7 enzymatic assay is 50 μL and contains 50 mM HEPES Hemisodium (pH 7.5), 0.05% BSA, 0.01% Tween-20, 25 mM NaCl, 5 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2021
Entry Details
US Patent

TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 476122BDBM476122({(2R,3S,5R)-5-[4-amino-3-(tert-butylsulfanyl)-1H-p...)
Affinity DataIC50: 35nMAssay Description:The total volume of the ATG7 enzymatic assay is 50 μL and contains 50 mM HEPES Hemisodium (pH 7.5), 0.05% BSA, 0.01% Tween-20, 25 mM NaCl, 5 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2021
Entry Details
US Patent

TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 475993BDBM475993({(2R,3S,4R,5R)-5-[4-amino-3-(ethylsulfanyl)-1H-pyr...)
Affinity DataIC50: 35nMAssay Description:The total volume of the ATG7 enzymatic assay is 50 μL and contains 50 mM HEPES Hemisodium (pH 7.5), 0.05% BSA, 0.01% Tween-20, 25 mM NaCl, 5 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2021
Entry Details
US Patent

TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 476119BDBM476119({(2R,3S,5R)-5-[4-amino-3-(1,3-thiazol-2-ylsulfanyl...)
Affinity DataIC50: 35nMAssay Description:The total volume of the ATG7 enzymatic assay is 50 μL and contains 50 mM HEPES Hemisodium (pH 7.5), 0.05% BSA, 0.01% Tween-20, 25 mM NaCl, 5 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2021
Entry Details
US Patent

TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
Takeda Pharmaceuticals International

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 476118BDBM476118([(2R,3S,5R)-5-{4-amino-3-[(2-fluoro-5-methoxypheny...)
Affinity DataIC50: 35nMAssay Description:The total volume of the ATG7 enzymatic assay is 50 μL and contains 50 mM HEPES Hemisodium (pH 7.5), 0.05% BSA, 0.01% Tween-20, 25 mM NaCl, 5 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2021
Entry Details
US Patent

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