Affinity DataKi: 12nMAssay Description:Inhibition of Escherichia coli GUS pre-incubated for 5 to 30 mins before 4-methylumbelliferone beta-D-glucuronide substrate addition at pH 6.7More data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataEC50: 18nMAssay Description:Inhibition of Escherichia coli beta-glucuronidase using p-nitrophenyl-beta-D-glucuronide as substrateMore data for this Ligand-Target Pair
Affinity DataEC50: 28nMAssay Description:Inhibition of Escherichia coli beta-glucuronidase using p-nitrophenyl-beta-D-glucuronide as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of Escherichia coli beta-glucuronidaseMore data for this Ligand-Target Pair
Affinity DataKi: 34nMAssay Description:Inhibition of Escherichia coli GUS pre-incubated for 5 to 30 mins before 4-methylumbelliferone beta-D-glucuronide substrate addition at pH 5.5More data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of Escherichia coli beta-glucuronidaseMore data for this Ligand-Target Pair
Affinity DataKi: 74nMAssay Description:Inhibition of Escherichia coli GUS pre-incubated for 5 to 30 mins before 4-methylumbelliferone beta-D-glucuronide substrate addition at pH 6.7More data for this Ligand-Target Pair
Affinity DataIC50: 118nMAssay Description:Successful drug candidate compounds were subjected to numerous biochemical and cellular assays. Purified bacterial β-glucuronidases were challen...More data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Inhibition of Escherichia coli beta-glucuronidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 142nMAssay Description:Successful drug candidate compounds were subjected to numerous biochemical and cellular assays. Purified bacterial β-glucuronidases were challen...More data for this Ligand-Target Pair
Affinity DataKi: 160nMAssay Description:Reactions were conducted similarly to the kinetic assays but the reaction consisted of 10 µL assay buffer, 5 µL inhibitor solution, 5 µL of 10 nM enz...More data for this Ligand-Target Pair
Affinity DataKi: 182nMAssay Description:Inhibition of Escherichia coli GUS pre-incubated for 5 to 30 mins before 4-methylumbelliferone beta-D-glucuronide substrate addition at pH 5.5More data for this Ligand-Target Pair
Affinity DataKi: 210nMAssay Description:Reactions were conducted similarly to the kinetic assays but the reaction consisted of 10 µL assay buffer, 5 µL inhibitor solution, 5 µL of 10 nM enz...More data for this Ligand-Target Pair
Affinity DataKi: 220nMAssay Description:Reactions were conducted similarly to the kinetic assays but the reaction consisted of 10 µL assay buffer, 5 µL inhibitor solution, 5 µL of 10 nM enz...More data for this Ligand-Target Pair
Affinity DataKi: 232nMAssay Description:Inhibition of Escherichia coli GUS pre-incubated for 5 to 30 mins before 4-methylumbelliferone beta-D-glucuronide substrate addition at pH 5.5More data for this Ligand-Target Pair
Affinity DataIC50: 240nMAssay Description:Inhibition of Escherichia coli beta-glucuronidase assessed as reduction of p-nitrophenol release using beta-PNPG as substrate incubated for 30 mins b...More data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 347nMAssay Description:Successful drug candidate compounds were subjected to numerous biochemical and cellular assays. Purified bacterial β-glucuronidases were challen...More data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of Escherichia coli beta-glucuronidase assessed as reduction of p-nitrophenol release using beta-PNPG as substrate incubated for 30 mins b...More data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 400nMAssay Description:Inhibition of Escherichia coli beta-glucuronidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 468nMAssay Description:Successful drug candidate compounds were subjected to numerous biochemical and cellular assays. Purified bacterial β-glucuronidases were challen...More data for this Ligand-Target Pair
Affinity DataIC50: 580nMAssay Description:Inhibition of Escherichia coli beta-glucuronidase assessed as reduction of p-nitrophenol release using beta-PNPG as substrate incubated for 30 mins b...More data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataKi: 580nMAssay Description:Non-competitive inhibition of Escherichia coli beta-glucuronidase assessed as inhibition constant using beta-PNPG as substrate incubated for 30 mins ...More data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataKi: 610nMAssay Description:Reactions were conducted similarly to the kinetic assays but the reaction consisted of 10 µL assay buffer, 5 µL inhibitor solution, 5 µL of 10 nM enz...More data for this Ligand-Target Pair
Affinity DataIC50: 620nMAssay Description:Inhibition of Escherichia coli beta-glucuronidase using 4-methylumbelliferyl-beta-D-glucuronide hydrate as substrate preincubated for 5 mins followed...More data for this Ligand-Target Pair
Affinity DataIC50: 630nMAssay Description:Inhibition of Escherichia coli beta-glucuronidase assessed as reduction of p-nitrophenol release using beta-PNPG as substrate incubated for 30 mins b...More data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 640nMAssay Description:Inhibition of Escherichia coli beta-glucuronidase assessed as reduction of p-nitrophenol release using beta-PNPG as substrate incubated for 30 mins b...More data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataKi: 670nMAssay Description:Reactions were conducted similarly to the kinetic assays but the reaction consisted of 10 µL assay buffer, 5 µL inhibitor solution, 5 µL of 10 nM enz...More data for this Ligand-Target Pair
Affinity DataKi: 670nMAssay Description:Inhibition of Escherichia coli beta-glucuronidase assessed as inhibition constant using beta-PNPG as substrate incubated for 30 mins by Lineweaver-Bu...More data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataKi: 680nMAssay Description:Reactions were conducted similarly to the kinetic assays but the reaction consisted of 10 µL assay buffer, 5 µL inhibitor solution, 5 µL of 10 nM enz...More data for this Ligand-Target Pair
Affinity DataKi: 710nMAssay Description:Inhibition of Escherichia coli beta-glucuronidase assessed as inhibition constant using beta-PNPG as substrate incubated for 30 mins by Lineweaver-Bu...More data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 740nMAssay Description:Non-competitive inhibition of Escherichia coli beta-glucuronidase assessed as reduction of p-nitrophenol release using beta-PNPG as substrate incubat...More data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 759nMAssay Description:Successful drug candidate compounds were subjected to numerous biochemical and cellular assays. Purified bacterial β-glucuronidases were challen...More data for this Ligand-Target Pair
Affinity DataKi: 860nMAssay Description:Inhibition of Escherichia coli beta-glucuronidase assessed as inhibition constant using beta-PNPG as substrate incubated for 30 mins by Lineweaver-Bu...More data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 950nMAssay Description:Inhibition of Escherichia coli beta-glucuronidase using 4-methylumbelliferyl-beta-D-glucuronide hydrate as substrate preincubated for 5 mins followed...More data for this Ligand-Target Pair
Affinity DataKi: 960nMAssay Description:Reactions were conducted similarly to the kinetic assays but the reaction consisted of 10 µL assay buffer, 5 µL inhibitor solution, 5 µL of 10 nM enz...More data for this Ligand-Target Pair
Affinity DataIC50: 1.01E+3nMAssay Description:Inhibition of Escherichia coli beta-glucuronidase assessed as reduction of p-nitrophenol release using beta-PNPG as substrate incubated for 30 mins b...More data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataKi: 1.09E+3nMAssay Description:Inhibition of Escherichia coli beta-glucuronidase assessed as inhibition constant using beta-PNPG as substrate incubated for 30 mins by Lineweaver-Bu...More data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 1.11E+3nMAssay Description:Successful drug candidate compounds were subjected to numerous biochemical and cellular assays. Purified bacterial β-glucuronidases were challen...More data for this Ligand-Target Pair
Affinity DataKi: 1.16E+3nMAssay Description:Inhibition of Escherichia coli beta-glucuronidase assessed as inhibition constant using beta-PNPG as substrate incubated for 30 mins by Lineweaver-Bu...More data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 1.26E+3nMAssay Description:Non-competitive inhibition of Escherichia coli beta-glucuronidase assessed as reduction of p-nitrophenol release using beta-PNPG as substrate incubat...More data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataKi: 1.26E+3nMAssay Description:Non-competitive inhibition of Escherichia coli beta-glucuronidase assessed as inhibition constant using beta-PNPG as substrate incubated for 30 mins ...More data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataKi: 1.40E+3nMAssay Description:Reactions were conducted similarly to the kinetic assays but the reaction consisted of 10 µL assay buffer, 5 µL inhibitor solution, 5 µL of 10 nM enz...More data for this Ligand-Target Pair
Affinity DataIC50: 1.42E+3nMAssay Description:Inhibition of Escherichia coli beta-glucuronidase assessed as reduction of p-nitrophenol release using beta-PNPG as substrate incubated for 30 mins b...More data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataKi: 1.55E+3nMAssay Description:Inhibition of Escherichia coli beta-glucuronidase assessed as inhibition constant using beta-PNPG as substrate incubated for 30 mins by Lineweaver-Bu...More data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of Escherichia coli beta-glucuronidaseMore data for this Ligand-Target Pair
Affinity DataKi: 1.64E+3nMAssay Description:Inhibition of Escherichia coli beta-glucuronidase assessed as inhibition constant using beta-PNPG as substrate incubated for 30 mins by Lineweaver-Bu...More data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 1.66E+3nMAssay Description:Successful drug candidate compounds were subjected to numerous biochemical and cellular assays. Purified bacterial β-glucuronidases were challen...More data for this Ligand-Target Pair
Affinity DataKi: 1.90E+3nMAssay Description:Reactions were conducted similarly to the kinetic assays but the reaction consisted of 10 µL assay buffer, 5 µL inhibitor solution, 5 µL of 10 nM enz...More data for this Ligand-Target Pair
Affinity DataKi: 1.90E+3nMAssay Description:Reactions were conducted similarly to the kinetic assays but the reaction consisted of 10 µL assay buffer, 5 µL inhibitor solution, 5 µL of 10 nM enz...More data for this Ligand-Target Pair
Affinity DataIC50: 1.91E+3nMAssay Description:Inhibition of Escherichia coli beta-glucuronidase assessed as reduction of p-nitrophenol release using beta-PNPG as substrate incubated for 30 mins b...More data for this Ligand-Target Pair
Ligand InfoSimilars
