Compile Data Set for Download or QSAR
Report error Found 18 of affinity data for UniProtKB/TrEMBL: P0CS13
TargetThymidylate synthase(Cryptococcus neoformans)
Unimore

LigandChemical structure of BindingDB Monomer ID 18755BDBM18755(3,3-bis(4-hydroxyphenyl)-4-oxatricyclo[7.4.0.0^{2,...)
Affinity DataKi:  400nMAssay Description:TS was assayed spectrophotometrically in the reaction buffer solution containing (6R, 6S)-5, 10-CH2H4folate. The reaction was initiated by the additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2007
Entry Details Article
PubMed
TargetThymidylate synthase(Cryptococcus neoformans)
Unimore

LigandChemical structure of BindingDB Monomer ID 18756BDBM18756(5,5-bis(4-hydroxyphenyl)-4-oxatricyclo[7.4.0.0^{2,...)
Affinity DataKi:  600nMAssay Description:TS was assayed spectrophotometrically in the reaction buffer solution containing (6R, 6S)-5, 10-CH2H4folate. The reaction was initiated by the additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2007
Entry Details Article
PubMed
TargetThymidylate synthase(Cryptococcus neoformans)
Unimore

LigandChemical structure of BindingDB Monomer ID 18758BDBM18758(Phenolnaphthalein derivative, 4 | 3,3-bis(3-bromo-...)
Affinity DataKi:  2.70E+3nMAssay Description:TS was assayed spectrophotometrically in the reaction buffer solution containing (6R, 6S)-5, 10-CH2H4folate. The reaction was initiated by the additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2007
Entry Details Article
PubMed
TargetThymidylate synthase(Cryptococcus neoformans)
Unimore

LigandChemical structure of BindingDB Monomer ID 18765BDBM18765(4,4-bis(3,5-dichloro-4-hydroxyphenyl)-3-oxatricycl...)
Affinity DataKi:  3.30E+3nMAssay Description:TS was assayed spectrophotometrically in the reaction buffer solution containing (6R, 6S)-5, 10-CH2H4folate. The reaction was initiated by the additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2007
Entry Details Article
PubMed
TargetThymidylate synthase(Cryptococcus neoformans)
Unimore

LigandChemical structure of BindingDB Monomer ID 18761BDBM18761(5,5-bis(3-fluoro-4-hydroxyphenyl)-4-oxatricyclo[7....)
Affinity DataKi:  3.50E+3nMAssay Description:TS was assayed spectrophotometrically in the reaction buffer solution containing (6R, 6S)-5, 10-CH2H4folate. The reaction was initiated by the additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2007
Entry Details Article
PubMed
TargetThymidylate synthase(Cryptococcus neoformans)
Unimore

LigandChemical structure of BindingDB Monomer ID 18768BDBM18768(4,4-bis(3,5-dibromo-4-hydroxyphenyl)-3-oxatricyclo...)
Affinity DataKi:  4.00E+3nMAssay Description:TS was assayed spectrophotometrically in the reaction buffer solution containing (6R, 6S)-5, 10-CH2H4folate. The reaction was initiated by the additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2007
Entry Details Article
PubMed
TargetThymidylate synthase(Cryptococcus neoformans)
Unimore

LigandChemical structure of BindingDB Monomer ID 18753BDBM18753(4,4-bis(3-bromo-4-hydroxyphenyl)-10-chloro-3-oxatr...)
Affinity DataKi:  4.10E+3nM ΔG°:  -30.2kJ/molepH: 7.4 T: 2°CAssay Description:TS was assayed spectrophotometrically in the reaction buffer solution containing (6R, 6S)-5, 10-CH2H4folate. The reaction was initiated by the additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2007
Entry Details Article
PubMed
TargetThymidylate synthase(Cryptococcus neoformans)
Unimore

LigandChemical structure of BindingDB Monomer ID 18772BDBM18772(Phenolnaphthalein derivative, 2 | 4,4-bis(3-bromo-...)
Affinity DataKi:  4.10E+3nMAssay Description:TS was assayed spectrophotometrically in the reaction buffer solution containing (6R, 6S)-5, 10-CH2H4folate. The reaction was initiated by the additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2007
Entry Details Article
PubMed
TargetThymidylate synthase(Cryptococcus neoformans)
Unimore

LigandChemical structure of BindingDB Monomer ID 18757BDBM18757(3,3-bis(4-hydroxy-3-iodophenyl)-4-oxatricyclo[7.4....)
Affinity DataKi:  4.50E+3nMAssay Description:TS was assayed spectrophotometrically in the reaction buffer solution containing (6R, 6S)-5, 10-CH2H4folate. The reaction was initiated by the additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2007
Entry Details Article
PubMed
TargetThymidylate synthase(Cryptococcus neoformans)
Unimore

LigandChemical structure of BindingDB Monomer ID 18766BDBM18766(4-(3-bromo-4-hydroxyphenyl)-4-(4-hydroxyphenyl)-3-...)
Affinity DataKi:  5.20E+3nMAssay Description:TS was assayed spectrophotometrically in the reaction buffer solution containing (6R, 6S)-5, 10-CH2H4folate. The reaction was initiated by the additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2007
Entry Details Article
PubMed
TargetThymidylate synthase(Cryptococcus neoformans)
Unimore

LigandChemical structure of BindingDB Monomer ID 18769BDBM18769(Phenolnaphthalein derivative, 1 | CHEMBL303171 | 4...)
Affinity DataKi:  6.40E+3nMAssay Description:TS was assayed spectrophotometrically in the reaction buffer solution containing (6R, 6S)-5, 10-CH2H4folate. The reaction was initiated by the additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2007
Entry Details Article
PubMed
TargetThymidylate synthase(Cryptococcus neoformans)
Unimore

LigandChemical structure of BindingDB Monomer ID 18770BDBM18770(Phenolnaphthalein derivative, 3 | 8-chloro-4,4-bis...)
Affinity DataKi:  6.50E+3nMAssay Description:TS was assayed spectrophotometrically in the reaction buffer solution containing (6R, 6S)-5, 10-CH2H4folate. The reaction was initiated by the additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2007
Entry Details Article
PubMed
TargetThymidylate synthase(Cryptococcus neoformans)
Unimore

LigandChemical structure of BindingDB Monomer ID 18760BDBM18760(5,5-bis(3-chloro-4-hydroxyphenyl)-4-oxatricyclo[7....)
Affinity DataKi:  8.10E+3nMAssay Description:TS was assayed spectrophotometrically in the reaction buffer solution containing (6R, 6S)-5, 10-CH2H4folate. The reaction was initiated by the additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2007
Entry Details Article
PubMed
TargetThymidylate synthase(Cryptococcus neoformans)
Unimore

LigandChemical structure of BindingDB Monomer ID 18764BDBM18764(8-chloro-4,4-bis(3-chloro-4-hydroxyphenyl)-3-oxatr...)
Affinity DataKi:  9.60E+3nMAssay Description:TS was assayed spectrophotometrically in the reaction buffer solution containing (6R, 6S)-5, 10-CH2H4folate. The reaction was initiated by the additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2007
Entry Details Article
PubMed
TargetThymidylate synthase(Cryptococcus neoformans)
Unimore

LigandChemical structure of BindingDB Monomer ID 18767BDBM18767(4,4-bis(3-bromo-4-hydroxyphenyl)-3-oxatricyclo[7.3...)
Affinity DataKi:  1.30E+4nMAssay Description:TS was assayed spectrophotometrically in the reaction buffer solution containing (6R, 6S)-5, 10-CH2H4folate. The reaction was initiated by the additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2007
Entry Details Article
PubMed
TargetThymidylate synthase(Cryptococcus neoformans)
Unimore

LigandChemical structure of BindingDB Monomer ID 18759BDBM18759(Phenolnaphthalein derivative, 5 | 3,3-bis(3,5-dibr...)
Affinity DataKi:  1.30E+4nMAssay Description:TS was assayed spectrophotometrically in the reaction buffer solution containing (6R, 6S)-5, 10-CH2H4folate. The reaction was initiated by the additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2007
Entry Details Article
PubMed
TargetThymidylate synthase(Cryptococcus neoformans)
Unimore

LigandChemical structure of BindingDB Monomer ID 18762BDBM18762(4,4-bis(4-hydroxy-3-iodophenyl)-3-oxatricyclo[7.3....)
Affinity DataKi:  1.60E+4nMAssay Description:TS was assayed spectrophotometrically in the reaction buffer solution containing (6R, 6S)-5, 10-CH2H4folate. The reaction was initiated by the additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2007
Entry Details Article
PubMed
TargetThymidylate synthase(Cryptococcus neoformans)
Unimore

LigandChemical structure of BindingDB Monomer ID 18763BDBM18763(CHEMBL67116 | 4,4-bis(3-chloro-4-hydroxyphenyl)-3-...)
Affinity DataKi:  3.50E+4nMAssay Description:TS was assayed spectrophotometrically in the reaction buffer solution containing (6R, 6S)-5, 10-CH2H4folate. The reaction was initiated by the additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2007
Entry Details Article
PubMed