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Report error Found 2235 for UniProtKB: P19793
TargetRetinoic acid receptor RXR-alpha(Human)
Acucela

US Patent
LigandPNGBDBM323588(Retinoic Acid | all-trans-retinoic acid | at-RA | ...)
Affinity DataEC50:  316nMAssay Description:Retinoid nuclear receptor activity is associated with transduction of the non-visual physiologic, pharmacologic, and toxicologic retinoid signals tha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
US Patent

TargetRetinoic acid receptor RXR-alpha(Human)
Acucela

US Patent
LigandPNGBDBM31883(ALL-TRANS-RETINOIC ACID | SMR000058245 | cid_44479...)
Affinity DataKd:  13nMpH: 7.4 T: 2°CAssay Description:Binding assay using human retinoid X receptor alpha (RXR).More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2011
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
Acucela

US Patent
LigandPNGBDBM50032675(4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...)
Affinity DataKd:  36nMpH: 7.4 T: 2°CAssay Description:Binding assay using human retinoid X receptor alpha (RXR).More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetRetinoic acid receptor RXR-alpha(Human)
Acucela

US Patent
LigandPNGBDBM50032675(4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...)
Affinity DataKd:  7nMpH: 7.4 T: 2°CAssay Description:Binding assay using human retinoid X receptor alpha (RXR).More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetRetinoic acid receptor RXR-alpha(Human)
Acucela

US Patent
LigandPNGBDBM50032675(4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...)
Affinity DataKd:  26nMpH: 7.4 T: 2°CAssay Description:Binding assay using human retinoid X receptor alpha (RXR).More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetRetinoic acid receptor RXR-alpha(Human)
Acucela

US Patent
LigandPNGBDBM50032675(4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...)
Affinity DataKd:  42nMpH: 7.4 T: 2°CAssay Description:Binding assay using human retinoid X receptor alpha (RXR).More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetRetinoic acid receptor RXR-alpha(Human)
Acucela

US Patent
LigandPNGBDBM31883(ALL-TRANS-RETINOIC ACID | SMR000058245 | cid_44479...)
Affinity DataKd:  40nMpH: 7.4 T: 2°CAssay Description:Binding assay using human retinoid X receptor alpha (RXR).More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2011
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
Acucela

US Patent
LigandPNGBDBM31883(ALL-TRANS-RETINOIC ACID | SMR000058245 | cid_44479...)
Affinity DataKd:  30nMpH: 7.4 T: 2°CAssay Description:Binding assay using human retinoid X receptor alpha (RXR).More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2011
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
Acucela

US Patent
LigandPNGBDBM50032675(4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...)
Affinity DataKd:  51nMpH: 7.4 T: 2°CAssay Description:Binding assay using human retinoid X receptor alpha (RXR).More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDimer of Retinoic acid receptor RXR-alpha(Human)
University of Texas Southwestern Medical Center

LigandPNGBDBM50032675(4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...)
Affinity DataKd:  28nMpH: 7.4 T: 2°CAssay Description:Binding assay using human retinoid X receptor alpha (RXR).More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDimer of Retinoic acid receptor RXR-alpha(Human)
University of Texas Southwestern Medical Center

LigandPNGBDBM50032675(4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...)
Affinity DataKd:  18nMpH: 7.4 T: 2°CAssay Description:Binding assay using human retinoid X receptor alpha (RXR).More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50012902(CHEMBL3261318 | USRE46024, 1)
Affinity DataEC50:  7.75E+3nMpH: 7.0Assay Description:Thirty microliters of H6-TRβ (50 nM) in 50 mM Hepes, pH 7.0, 1 mM DTT, 0.05% NP40 and 0.2 mg/ml BSA (Binding Buffer) was mixed with an equal vol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details
US Patent

LigandPNGBDBM50012859(CHEMBL3261319 | USRE46024, 2)
Affinity DataEC50:  7.31E+3nMpH: 7.0Assay Description:Thirty microliters of H6-TRβ (50 nM) in 50 mM Hepes, pH 7.0, 1 mM DTT, 0.05% NP40 and 0.2 mg/ml BSA (Binding Buffer) was mixed with an equal vol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details
US Patent

LigandPNGBDBM50012912(CHEMBL3261321 | USRE46024, 3)
Affinity DataEC50:  519nMpH: 7.0Assay Description:Thirty microliters of H6-TRβ (50 nM) in 50 mM Hepes, pH 7.0, 1 mM DTT, 0.05% NP40 and 0.2 mg/ml BSA (Binding Buffer) was mixed with an equal vol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details
US Patent

LigandPNGBDBM50012901(CHEMBL3261320 | USRE46024, 4)
Affinity DataEC50:  2.33E+3nMpH: 7.0Assay Description:Thirty microliters of H6-TRβ (50 nM) in 50 mM Hepes, pH 7.0, 1 mM DTT, 0.05% NP40 and 0.2 mg/ml BSA (Binding Buffer) was mixed with an equal vol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details
US Patent

LigandPNGBDBM50012916(CHEMBL3261322 | USRE46024, 5)
Affinity DataEC50:  699nMpH: 7.0Assay Description:Thirty microliters of H6-TRβ (50 nM) in 50 mM Hepes, pH 7.0, 1 mM DTT, 0.05% NP40 and 0.2 mg/ml BSA (Binding Buffer) was mixed with an equal vol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details
US Patent

LigandPNGBDBM50012918(CHEMBL3261324 | USRE46024, 6)
Affinity DataEC50:  666nMpH: 7.0Assay Description:Thirty microliters of H6-TRβ (50 nM) in 50 mM Hepes, pH 7.0, 1 mM DTT, 0.05% NP40 and 0.2 mg/ml BSA (Binding Buffer) was mixed with an equal vol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details
US Patent

LigandPNGBDBM60964(USRE46024, 7)
Affinity DataEC50:  117nMpH: 7.0Assay Description:Thirty microliters of H6-TRβ (50 nM) in 50 mM Hepes, pH 7.0, 1 mM DTT, 0.05% NP40 and 0.2 mg/ml BSA (Binding Buffer) was mixed with an equal vol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details
US Patent

LigandPNGBDBM50012905(CHEMBL3261331 | USRE46024, 8 | US20240059676, Comp...)
Affinity DataEC50:  192nMpH: 7.0Assay Description:Thirty microliters of H6-TRβ (50 nM) in 50 mM Hepes, pH 7.0, 1 mM DTT, 0.05% NP40 and 0.2 mg/ml BSA (Binding Buffer) was mixed with an equal vol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details
US Patent

LigandPNGBDBM50012915(CHEMBL3261335 | USRE46024, 9)
Affinity DataEC50:  115nMpH: 7.0Assay Description:Thirty microliters of H6-TRβ (50 nM) in 50 mM Hepes, pH 7.0, 1 mM DTT, 0.05% NP40 and 0.2 mg/ml BSA (Binding Buffer) was mixed with an equal vol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details
US Patent

LigandPNGBDBM50012906(CHEMBL3261323 | USRE46024, 10)
Affinity DataEC50:  767nMpH: 7.0Assay Description:Thirty microliters of H6-TRβ (50 nM) in 50 mM Hepes, pH 7.0, 1 mM DTT, 0.05% NP40 and 0.2 mg/ml BSA (Binding Buffer) was mixed with an equal vol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details
US Patent

LigandPNGBDBM237173(USRE46024, 11)
Affinity DataEC50:  1.20E+3nMpH: 7.0Assay Description:Thirty microliters of H6-TRβ (50 nM) in 50 mM Hepes, pH 7.0, 1 mM DTT, 0.05% NP40 and 0.2 mg/ml BSA (Binding Buffer) was mixed with an equal vol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details
US Patent

LigandPNGBDBM50012911(CHEMBL3261332 | USRE46024, 12)
Affinity DataEC50:  133nMpH: 7.0Assay Description:Thirty microliters of H6-TRβ (50 nM) in 50 mM Hepes, pH 7.0, 1 mM DTT, 0.05% NP40 and 0.2 mg/ml BSA (Binding Buffer) was mixed with an equal vol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details
US Patent

LigandPNGBDBM50012907(CHEMBL3261336 | USRE46024, 13)
Affinity DataEC50:  92nMpH: 7.0Assay Description:Thirty microliters of H6-TRβ (50 nM) in 50 mM Hepes, pH 7.0, 1 mM DTT, 0.05% NP40 and 0.2 mg/ml BSA (Binding Buffer) was mixed with an equal vol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details
US Patent

LigandPNGBDBM50012910(CHEMBL3261326 | USRE46024, 14)
Affinity DataEC50:  2.99E+3nMpH: 7.0Assay Description:Thirty microliters of H6-TRβ (50 nM) in 50 mM Hepes, pH 7.0, 1 mM DTT, 0.05% NP40 and 0.2 mg/ml BSA (Binding Buffer) was mixed with an equal vol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details
US Patent

LigandPNGBDBM50012917(CHEMBL3261327 | USRE46024, 15)
Affinity DataEC50:  601nMpH: 7.0Assay Description:Thirty microliters of H6-TRβ (50 nM) in 50 mM Hepes, pH 7.0, 1 mM DTT, 0.05% NP40 and 0.2 mg/ml BSA (Binding Buffer) was mixed with an equal vol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details
US Patent

LigandPNGBDBM50012913(CHEMBL3261333 | USRE46024, 16)
Affinity DataEC50:  66nMpH: 7.0Assay Description:Thirty microliters of H6-TRβ (50 nM) in 50 mM Hepes, pH 7.0, 1 mM DTT, 0.05% NP40 and 0.2 mg/ml BSA (Binding Buffer) was mixed with an equal vol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details
US Patent

LigandPNGBDBM50012903(CHEMBL3261328 | USRE46024, 17)
Affinity DataEC50:  2.04E+3nMpH: 7.0Assay Description:Thirty microliters of H6-TRβ (50 nM) in 50 mM Hepes, pH 7.0, 1 mM DTT, 0.05% NP40 and 0.2 mg/ml BSA (Binding Buffer) was mixed with an equal vol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details
US Patent

LigandPNGBDBM237174(USRE46024, 18)
Affinity DataEC50:  9.18E+3nMpH: 7.0Assay Description:Thirty microliters of H6-TRβ (50 nM) in 50 mM Hepes, pH 7.0, 1 mM DTT, 0.05% NP40 and 0.2 mg/ml BSA (Binding Buffer) was mixed with an equal vol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details
US Patent

LigandPNGBDBM50012817(CHEMBL3261330 | USRE46024, 19)
Affinity DataEC50:  6.98E+3nMpH: 7.0Assay Description:Thirty microliters of H6-TRβ (50 nM) in 50 mM Hepes, pH 7.0, 1 mM DTT, 0.05% NP40 and 0.2 mg/ml BSA (Binding Buffer) was mixed with an equal vol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details
US Patent

LigandPNGBDBM237175(USRE46024, 20)
Affinity DataEC50:  7.04E+3nMpH: 7.0Assay Description:Thirty microliters of H6-TRβ (50 nM) in 50 mM Hepes, pH 7.0, 1 mM DTT, 0.05% NP40 and 0.2 mg/ml BSA (Binding Buffer) was mixed with an equal vol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details
US Patent

LigandPNGBDBM237176(USRE46024, 21)
Affinity DataEC50:  3.21E+3nMpH: 7.0Assay Description:Thirty microliters of H6-TRβ (50 nM) in 50 mM Hepes, pH 7.0, 1 mM DTT, 0.05% NP40 and 0.2 mg/ml BSA (Binding Buffer) was mixed with an equal vol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details
US Patent

LigandPNGBDBM50012908(CHEMBL3261334 | USRE46024, 22)
Affinity DataEC50:  136nMpH: 7.0Assay Description:Thirty microliters of H6-TRβ (50 nM) in 50 mM Hepes, pH 7.0, 1 mM DTT, 0.05% NP40 and 0.2 mg/ml BSA (Binding Buffer) was mixed with an equal vol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details
US Patent

TargetRetinoic acid receptor RXR-alpha(Human)
Acucela

US Patent
LigandPNGBDBM485847(US10946019, Example 1)
Affinity DataEC50: >5.00E+4nMAssay Description:The in vitro transactivation assay determined the capacity of the compounds of the invention to activate the Nurr1:RXR heterodimers. Naive SHSY-5Y ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
US Patent

TargetRetinoic acid receptor RXR-alpha(Human)
Acucela

US Patent
LigandPNGBDBM485848(US10946019, Example 3)
Affinity DataEC50:  900nMAssay Description:The in vitro transactivation assay determined the capacity of the compounds of the invention to activate the Nurr1:RXR heterodimers. Naive SHSY-5Y ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
US Patent

TargetRetinoic acid receptor RXR-alpha(Human)
Acucela

US Patent
LigandPNGBDBM485849(US10946019, Example 4)
Affinity DataEC50:  200nMAssay Description:The in vitro transactivation assay determined the capacity of the compounds of the invention to activate the Nurr1:RXR heterodimers. Naive SHSY-5Y ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
US Patent

TargetRetinoic acid receptor RXR-alpha(Human)
Acucela

US Patent
LigandPNGBDBM485851(US10946019, Example 5)
Affinity DataEC50:  300nMAssay Description:The in vitro transactivation assay determined the capacity of the compounds of the invention to activate the Nurr1:RXR heterodimers. Naive SHSY-5Y ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
US Patent

TargetRetinoic acid receptor RXR-alpha(Human)
Acucela

US Patent
LigandPNGBDBM485856(US10946019, Example 6)
Affinity DataEC50: >1.00E+5nMAssay Description:The in vitro transactivation assay determined the capacity of the compounds of the invention to activate the Nurr1:RXR heterodimers. Naive SHSY-5Y ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
US Patent

TargetRetinoic acid receptor RXR-alpha(Human)
Acucela

US Patent
LigandPNGBDBM485861(US10946019, Example 9)
Affinity DataEC50: >1.00E+5nMAssay Description:The in vitro transactivation assay determined the capacity of the compounds of the invention to activate the Nurr1:RXR heterodimers. Naive SHSY-5Y ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
US Patent

TargetRetinoic acid receptor RXR-alpha(Human)
Acucela

US Patent
LigandPNGBDBM485864(US10946019, Example 10)
Affinity DataEC50: >2.00E+4nMAssay Description:The in vitro transactivation assay determined the capacity of the compounds of the invention to activate the Nurr1:RXR heterodimers. Naive SHSY-5Y ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
US Patent

TargetRetinoic acid receptor RXR-alpha(Human)
Acucela

US Patent
LigandPNGBDBM50346092(4-(6-methyl-2-phenyl-5-propylpyrimidin-4-ylamino)b...)
Affinity DataEC50:  1.00E+3nMAssay Description:The in vitro transactivation assay determined the capacity of the compounds of the invention to activate the Nurr1:RXR heterodimers. Naive SHSY-5Y ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
US Patent

TargetRetinoic acid receptor RXR-alpha(Human)
Acucela

US Patent
LigandPNGBDBM50346093(4-(5-isopropyl-6-methyl-2-phenylpyrimidin-4-ylamin...)
Affinity DataEC50:  1.00E+3nMAssay Description:The in vitro transactivation assay determined the capacity of the compounds of the invention to activate the Nurr1:RXR heterodimers. Naive SHSY-5Y ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
US Patent

TargetRetinoic acid receptor RXR-alpha(Human)
Acucela

US Patent
LigandPNGBDBM50346091(4-(5-ethyl-6-methyl-2-phenylpyrimidin-4-ylamino)be...)
Affinity DataEC50:  5.00E+3nMAssay Description:The in vitro transactivation assay determined the capacity of the compounds of the invention to activate the Nurr1:RXR heterodimers. Naive SHSY-5Y ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
US Patent

TargetRetinoic acid receptor RXR-alpha(Human)
Acucela

US Patent
LigandPNGBDBM485868(US10946019, Example 14)
Affinity DataEC50:  2.00E+3nMAssay Description:The in vitro transactivation assay determined the capacity of the compounds of the invention to activate the Nurr1:RXR heterodimers. Naive SHSY-5Y ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
US Patent

TargetRetinoic acid receptor RXR-alpha(Human)
Acucela

US Patent
LigandPNGBDBM485869(US10946019, Example 15)
Affinity DataEC50: >1.00E+4nMAssay Description:The in vitro transactivation assay determined the capacity of the compounds of the invention to activate the Nurr1:RXR heterodimers. Naive SHSY-5Y ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
US Patent

TargetRetinoic acid receptor RXR-alpha(Human)
Acucela

US Patent
LigandPNGBDBM485870(US10946019, Example 16)
Affinity DataEC50:  2.00E+3nMAssay Description:The in vitro transactivation assay determined the capacity of the compounds of the invention to activate the Nurr1:RXR heterodimers. Naive SHSY-5Y ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
US Patent

TargetRetinoic acid receptor RXR-alpha(Human)
Acucela

US Patent
LigandPNGBDBM485871(US10946019, Example 19)
Affinity DataEC50:  1.00E+4nMAssay Description:The in vitro transactivation assay determined the capacity of the compounds of the invention to activate the Nurr1:RXR heterodimers. Naive SHSY-5Y ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
US Patent

TargetRetinoic acid receptor RXR-alpha(Human)
Acucela

US Patent
LigandPNGBDBM485872(US10946019, Example 20)
Affinity DataEC50: >1.00E+4nMAssay Description:The in vitro transactivation assay determined the capacity of the compounds of the invention to activate the Nurr1:RXR heterodimers. Naive SHSY-5Y ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
US Patent

TargetRetinoic acid receptor RXR-alpha(Human)
Acucela

US Patent
LigandPNGBDBM485874(US10946019, Example 23)
Affinity DataEC50:  7.00E+3nMAssay Description:The in vitro transactivation assay determined the capacity of the compounds of the invention to activate the Nurr1:RXR heterodimers. Naive SHSY-5Y ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
US Patent

TargetRetinoic acid receptor RXR-alpha(Human)
Acucela

US Patent
LigandPNGBDBM485875(US10946019, Example 24)
Affinity DataEC50: >1.00E+5nMAssay Description:The in vitro transactivation assay determined the capacity of the compounds of the invention to activate the Nurr1:RXR heterodimers. Naive SHSY-5Y ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2021
Entry Details
US Patent

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