Compile Data Set for Download or QSAR
Report error Found 1388 of affinity data for UniProtKB/TrEMBL: P49146
TargetNeuropeptide Y receptor type 2(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50208988(HUMAN NEUROPEPTIDE Y)
Affinity DataIC50: 0.0280nMAssay Description:Displacement of [125I]peptide YY from Y2 receptor in human KAN-TS cells measured after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2018
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM85681(PYY 3-36)
Affinity DataKi:  0.0300nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2012
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50015490(NPY, human, rat | CHEMBL438945 | NPY | H-YPSKPDNPG...)
Affinity DataKi:  0.0400nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2012
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50240829(CHEMBL3559801)
Affinity DataEC50:  0.0631nMAssay Description:Positive allosteric modulation of human C-terminal eYFP-fused human NY2 receptor expressed in African green monkey COS7 cells co-expressing delta6Gal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50269165(CHEMBL4090092)
Affinity DataEC50:  0.0680nMAssay Description:Agonist activity at human Y2 receptor expressed in CHO cell membranes after 120 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2020
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50091652(PYY | CHEMBL269503 | PYY, rat | Peptide YY(PYY)(YP...)
Affinity DataIC50: 0.0700nMAssay Description:Affinity against Neuropeptide Y receptor Y2 in SK-N-BE2 cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50015490(NPY, human, rat | CHEMBL438945 | NPY | H-YPSKPDNPG...)
Affinity DataKi:  0.0760nMAssay Description:Binding affinity to human neuropeptide Y receptor type 2 by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50015490(NPY, human, rat | CHEMBL438945 | NPY | H-YPSKPDNPG...)
Affinity DataIC50: 0.0900nMAssay Description:Binding affinity to human neuropeptide Y2 receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50451003(CHEMBL4207076)
Affinity DataEC50:  0.110nMAssay Description:Agonist activity at human neuropeptide Y2 receptor expressed in CHO cell membranes assessed as stimulation of [35S]GTPgammaS binding incubated for 12...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50451012(CHEMBL4208191)
Affinity DataEC50:  0.110nMAssay Description:Agonist activity at human neuropeptide Y2 receptor expressed in CHO cell membranes assessed as stimulation of [35S]GTPgammaS binding incubated for 12...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50435127(CHEMBL2392022)
Affinity DataKi:  0.120nMAssay Description:Displacement of [125I]Peptide YY from neuropeptide Y receptor type 2 in human KAN-TS cells after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50546630(CHEMBL4746101)
Affinity DataEC50:  0.130nMAssay Description:Agonist activity at human NPY2R expressed in CHO cells assessed as inhibition of forskolin-induced intracellular cAMP accumulation incubated for 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50451008(CHEMBL4211953)
Affinity DataEC50:  0.130nMAssay Description:Agonist activity at human neuropeptide Y2 receptor expressed in CHO cell membranes assessed as stimulation of [35S]GTPgammaS binding incubated for 12...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50451027(CHEMBL4211310)
Affinity DataEC50:  0.130nMAssay Description:Agonist activity at human neuropeptide Y2 receptor expressed in CHO cell membranes assessed as stimulation of [35S]GTPgammaS binding incubated for 12...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50450994(CHEMBL4206938)
Affinity DataEC50:  0.130nMAssay Description:Agonist activity at human neuropeptide Y2 receptor expressed in CHO cell membranes assessed as stimulation of [35S]GTPgammaS binding incubated for 12...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50451011(CHEMBL4216889)
Affinity DataEC50:  0.140nMAssay Description:Agonist activity at human neuropeptide Y2 receptor expressed in CHO cell membranes assessed as stimulation of [35S]GTPgammaS binding incubated for 12...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50450993(CHEMBL4210786)
Affinity DataEC50:  0.150nMAssay Description:Agonist activity at human neuropeptide Y2 receptor expressed in CHO cell membranes assessed as stimulation of [35S]GTPgammaS binding incubated for 12...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50450997(CHEMBL4202723)
Affinity DataEC50:  0.160nMAssay Description:Agonist activity at human neuropeptide Y2 receptor expressed in CHO cell membranes assessed as stimulation of [35S]GTPgammaS binding incubated for 12...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50451011(CHEMBL4216889)
Affinity DataIC50: 0.160nMAssay Description:Displacement of [125I]-PYY from human neuropeptide Y2 receptor expressed in CHO cell membranes incubated for 60 mins by TopCount based methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50269168(CHEMBL4069205)
Affinity DataEC50:  0.160nMAssay Description:Agonist activity at human Y2 receptor expressed in CHO cell membranes after 120 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2020
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM82279(CAS_118997-30-1 | PYY, human)
Affinity DataKi:  0.170nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2011
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50451026(CHEMBL4208856)
Affinity DataEC50:  0.170nMAssay Description:Agonist activity at human neuropeptide Y2 receptor expressed in CHO cell membranes assessed as stimulation of [35S]GTPgammaS binding incubated for 12...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50451029(CHEMBL4206417)
Affinity DataEC50:  0.170nMAssay Description:Agonist activity at human neuropeptide Y2 receptor expressed in CHO cell membranes assessed as stimulation of [35S]GTPgammaS binding incubated for 12...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50451030(CHEMBL4216864)
Affinity DataEC50:  0.170nMAssay Description:Agonist activity at human neuropeptide Y2 receptor expressed in CHO cell membranes assessed as stimulation of [35S]GTPgammaS binding incubated for 12...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50450998(CHEMBL4207590)
Affinity DataEC50:  0.180nMAssay Description:Agonist activity at human neuropeptide Y2 receptor expressed in CHO cell membranes assessed as stimulation of [35S]GTPgammaS binding incubated for 12...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50546647(CHEMBL4793898)
Affinity DataEC50:  0.180nMAssay Description:Agonist activity at human NPY2R expressed in CHO cells assessed as inhibition of forskolin-induced intracellular cAMP accumulation incubated for 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50546630(CHEMBL4746101)
Affinity DataEC50:  0.180nMAssay Description:Agonist activity at human NPY2R expressed in CHO cells assessed as inhibition of forskolin-induced intracellular cAMP accumulation incubated for 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50451025(CHEMBL4204797)
Affinity DataEC50:  0.180nMAssay Description:Agonist activity at human neuropeptide Y2 receptor expressed in CHO cell membranes assessed as stimulation of [35S]GTPgammaS binding incubated for 12...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50460001(CHEMBL4226347)
Affinity DataIC50: 0.190nMAssay Description:Displacement of [125I]-PYY from human neuropeptide Y2 receptor expressed in CHO cell membranes incubated for 60 mins by TopCount micro scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50015490(NPY, human, rat | CHEMBL438945 | NPY | H-YPSKPDNPG...)
Affinity DataIC50: 0.190nMAssay Description:Binding affinity to human neuropeptide Y receptor type 2 by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50269185(CHEMBL4069788)
Affinity DataEC50:  0.190nMAssay Description:Agonist activity at human Y2 receptor expressed in CHO cell membranes after 120 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2020
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50460003(CHEMBL4224835)
Affinity DataIC50: 0.190nMAssay Description:Displacement of [125I]-PYY from human neuropeptide Y2 receptor expressed in CHO cell membranes incubated for 60 mins by TopCount micro scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50231578(CHEMBL3349022)
Affinity DataKi:  0.200nMAssay Description:Affinity against Neuropeptide Y2 receptor on SK-N-BE2 human neuroblastoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50231578(CHEMBL3349022)
Affinity DataKi:  0.200nMAssay Description:Affinity against Neuropeptide Y2 receptor on SK-N-BE2 human neuroblastoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50450996(CHEMBL4212927)
Affinity DataEC50:  0.200nMAssay Description:Agonist activity at human neuropeptide Y2 receptor expressed in CHO cell membranes assessed as stimulation of [35S]GTPgammaS binding incubated for 12...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50269184(CHEMBL4064778)
Affinity DataEC50:  0.200nMAssay Description:Agonist activity at human neuropeptide Y2 receptor expressed in CHO cell membranes assessed as stimulation of [35S]GTPgammaS binding incubated for 12...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50254345(CHEMBL4075597)
Affinity DataEC50:  0.200nMAssay Description:Agonist activity at human Y2R expressed in CHO cell membranes assessed as [35S]GTPgammaS binding after 120 mins by liquid scintillation methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2019
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50269184(CHEMBL4064778)
Affinity DataEC50:  0.200nMAssay Description:Agonist activity at human Y2 receptor expressed in CHO cell membranes after 120 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2020
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50269163(CHEMBL4094429)
Affinity DataEC50:  0.200nMAssay Description:Agonist activity at human Y2 receptor expressed in CHO cell membranes after 120 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2020
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50231578(CHEMBL3349022)
Affinity DataKi:  0.200nMAssay Description:Affinity against Neuropeptide Y2 receptor on SK-N-BE2 human neuroblastoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50269166(CHEMBL4063306)
Affinity DataEC50:  0.200nMAssay Description:Agonist activity at human Y2 receptor expressed in CHO cell membranes after 120 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2020
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50231578(CHEMBL3349022)
Affinity DataKi:  0.200nMAssay Description:Affinity against Neuropeptide Y2 receptor on SK-N-BE2 human neuroblastoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50197025(PYY(3-36) | CHEMBL439904)
Affinity DataEC50:  0.200nMAssay Description:Agonist activity at human NPY2R expressed in HEK293 cells co-transfected with CRE-luciferase incubated for 24 hrs in presence of 10% FBS by One-Glo l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50435127(CHEMBL2392022)
Affinity DataIC50: 0.210nMAssay Description:Displacement of [125I]Peptide YY from neuropeptide Y receptor type 2 in human KAN-TS cells after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50450995(CHEMBL4208023)
Affinity DataEC50:  0.210nMAssay Description:Agonist activity at human neuropeptide Y2 receptor expressed in CHO cell membranes assessed as stimulation of [35S]GTPgammaS binding incubated for 12...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50269142(CHEMBL4065281)
Affinity DataEC50:  0.210nMAssay Description:Agonist activity at human Y2 receptor expressed in CHO cell membranes after 120 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2020
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50451010(CHEMBL4205712)
Affinity DataEC50:  0.210nMAssay Description:Agonist activity at human neuropeptide Y2 receptor expressed in CHO cell membranes assessed as stimulation of [35S]GTPgammaS binding incubated for 12...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50099198(Tyr-Pro-Ser-Lys-Pro-Asp-Asn-Pro-Gly-Glu-Asp-Ala-Pr...)
Affinity DataKi:  0.230nMAssay Description:Affinity for cloned Y2 receptor using [125I]PYY as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50466553(CHEMBL4279794)
Affinity DataKi:  0.25nMAssay Description:Displacement of [125I]-PYY(1 to 36 residues) from human Y2R expressed in CHO cell membranes after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 2(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50466532(CHEMBL4281479)
Affinity DataKi:  0.25nMAssay Description:Displacement of [125I]-PYY(1 to 36 residues) from human Y2R expressed in CHO cell membranes after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
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