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TargetGlutamate receptor ionotropic, NMDA 1/2A(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50425996(CHEMBL2314718)
Affinity DataIC50: 5nMAssay Description:Inhibition of rat GluN1/2A receptor expressed in Xenopus laevis oocyte assessed as glutamate and glycine-induced current at holding potentials from -...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50426000(CHEMBL2311573)
Affinity DataIC50: 5nMAssay Description:Inhibition of rat GluN1/2A receptor expressed in Xenopus laevis oocyte assessed as glutamate and glycine-induced current at holding potentials from -...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50111396([[(S)-1-(4-Bromo-phenyl)-ethylamino]-(2,3-dioxo-1,...)
Affinity DataKi:  5.40nMAssay Description:Inhibitory constant against (S)-glutamate and glycine evoked currents mediated by N-methyl-D-aspartate glutamate receptor NR1a/NR2A expressed in Xeno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50426009(CHEMBL2314938)
Affinity DataIC50: 8nMAssay Description:Inhibition of rat GluN1/2A receptor expressed in Xenopus laevis oocyte assessed as glutamate and glycine-induced current at holding potentials from -...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50316373(Argiotoxin-636 | CHEMBL1098240)
Affinity DataIC50: 10nMAssay Description:Inhibition of rat GluN1/2A receptor expressed in Xenopus laevis oocyte assessed as glutamate and glycine-induced current at holding potentials from -...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50018845(CHEMBL3286869)
Affinity DataIC50: 12nMAssay Description:Inhibition of rat recombinant GluN1/2A expressed in Xenopus oocytes assessed as inhibition of glutamate/glycine-evoked channel current at holding pot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50426010(CHEMBL2314939)
Affinity DataIC50: 14nMAssay Description:Inhibition of rat GluN1/2A receptor expressed in Xenopus laevis oocyte assessed as glutamate and glycine-induced current at holding potentials from -...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50426008(CHEMBL2314937)
Affinity DataIC50: 17nMAssay Description:Inhibition of rat GluN1/2A receptor expressed in Xenopus laevis oocyte assessed as glutamate and glycine-induced current at holding potentials from -...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50426007(CHEMBL2314935)
Affinity DataIC50: 21nMAssay Description:Inhibition of rat GluN1/2A receptor expressed in Xenopus laevis oocyte assessed as glutamate and glycine-induced current at holding potentials from -...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2A(Rat)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50171881((E)-(R)-2-Amino-4-methyl-5-phosphono-pent-3-enoic ...)
Affinity DataIC50: 35nMAssay Description:Inhibition of [3H]CPP binding to rat N-methyl-D-aspartic acid receptor 2AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50050704((R)-4-(3-phosphonopropyl)piperazine-2-carboxylic a...)
Affinity DataKi:  41nMAssay Description:Inhibitory constant against (S)-glutamate and glycine evoked currents mediated by N-methyl-D-aspartate glutamate receptor NR1a/NR2A expressed in Xeno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlutamate receptor ionotropic, NMDA 1/2A(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50583031(CHEMBL5081078)
Affinity DataEC50:  53nMAssay Description:Agonist activity at rat GluN1/GluN2A NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2A(Rat)
University of Copenhagen

LigandPNGBDBM213889(5,7-Dichlorokynurenic acid (5,7-DCKA))
Affinity DataKi:  65nM ΔG°:  -41.0kJ/mole IC50: 92nMpH: 7.4 T: 2°CAssay Description:Two-electrode voltage clamp (TEVC) recordings were performed on Xenopus oocytes at room temperature 3-6 days postinjection using an OC-725C TEVC ampl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2017
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50425997(CHEMBL2314719)
Affinity DataIC50: 72nMAssay Description:Inhibition of rat GluN1/2A receptor expressed in Xenopus laevis oocyte assessed as glutamate and glycine-induced current at holding potentials from -...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50316373(Argiotoxin-636 | CHEMBL1098240)
Affinity DataIC50: 74nMAssay Description:Inhibition of rat GluN1/2A expressed in xenopus laevis oocytes assessed as inhibition of glycine-evoked current at membrane potential of -60 mV by vo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50426002(CHEMBL2314929)
Affinity DataIC50: 81nMAssay Description:Inhibition of rat GluN1/2A receptor expressed in Xenopus laevis oocyte assessed as glutamate and glycine-induced current at holding potentials from -...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50583019(CHEMBL5081008)
Affinity DataEC50:  93nMAssay Description:Agonist activity at rat GluN1/GluN2A NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2A(Rat)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50004927(Selfotel | 4-Phosphonomethyl-piperidine-2-carboxyl...)
Affinity DataIC50: 95nMAssay Description:Inhibition of [3H]CPP binding to rat N-methyl-D-aspartic acid receptor 2AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2A(Rat)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50132483(Pentyl-(1-phenethyloxy-4,5-dihydro-1H-imidazol-2-y...)
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against N-methyl-D-aspartate glutamate receptor 2A in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50425999(CHEMBL2314928)
Affinity DataIC50: 103nMAssay Description:Inhibition of rat GluN1/2A receptor expressed in Xenopus laevis oocyte assessed as glutamate and glycine-induced current at holding potentials from -...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2A(Rat)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50010893(CHEMBL431029 | (R)-2-Amino-4-oxo-5-phosphono-penta...)
Affinity DataIC50: 110nMAssay Description:Inhibition of [3H]CPP binding to rat N-methyl-D-aspartic acid receptor 2AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50426003(CHEMBL2314931)
Affinity DataIC50: 122nMAssay Description:Inhibition of rat GluN1/2A receptor expressed in Xenopus laevis oocyte assessed as glutamate and glycine-induced current at holding potentials from -...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50583020(CHEMBL5087374)
Affinity DataEC50:  130nMAssay Description:Agonist activity at rat GluN1/GluN2A NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2A(Rat)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50399431(CHEMBL2178919)
Affinity DataIC50: 150nMAssay Description:Antagonist activity at rat glutamate N1/2A receptor expressed in Xenopus oocytes at membrane potential -60 mV by two-electrode voltage-clamp electrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50426001(CHEMBL2314930)
Affinity DataIC50: 165nMAssay Description:Inhibition of rat GluN1/2A receptor expressed in Xenopus laevis oocyte assessed as glutamate and glycine-induced current at holding potentials from -...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50236939(CHEMBL2333945)
Affinity DataIC50: 170nMAssay Description:Negative allosteric modulation of recombinant rat GluN1/GluN2A expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlutamate receptor ionotropic, NMDA 2A(Rat)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50316373(Argiotoxin-636 | CHEMBL1098240)
Affinity DataIC50: 177nMAssay Description:Antagonist activity at rat glutamate N1/2A receptor expressed in Xenopus oocytes at membrane potential -60 mV by two-electrode voltage-clamp electrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50044140(2-(2-Chloro-phenyl)-2-methylamino-cyclohexanone(Ke...)
Affinity DataKi:  180nMAssay Description:Displacement of [3H]-MK801 from rat brain GluN1/GluN2A expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50583021(CHEMBL5091289)
Affinity DataEC50:  180nMAssay Description:Agonist activity at rat GluN1/GluN2A NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50236940(CHEMBL4068372)
Affinity DataIC50: 204nMAssay Description:Antagonist activity at rat GluN1A/GluN2A receptor expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induced channel cur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2019
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2A(Rat)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50132481((1-Benzyloxy-4,5-dihydro-1H-imidazol-2-yl)-pentyl-...)
Affinity DataIC50: 210nMAssay Description:Inhibitory activity against N-methyl-D-aspartate glutamate receptor 2A in ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50419775(CHEMBL1950808)
Affinity DataKi:  210nMAssay Description:Antagonist activity at rat recombinant GluN1/GluN2A receptor expressed in Xenopus laevis oocytes assessed as inhibition of glutamate-induced response...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlutamate receptor ionotropic, NMDA 1/2A(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50583022(CHEMBL5085583)
Affinity DataEC50:  220nMAssay Description:Agonist activity at rat GluN1/GluN2A NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2A(Rat)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50171881((E)-(R)-2-Amino-4-methyl-5-phosphono-pent-3-enoic ...)
Affinity DataIC50: 220nMAssay Description:Inhibition of [3H]Glu binding to rat N-methyl-D-aspartic acid receptor 2AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2A(Rat)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50171882((E)-(R)-2-Amino-4-phosphonomethyl-hept-3-enoic aci...)
Affinity DataIC50: 230nMAssay Description:Inhibition of [3H]Glu binding to rat N-methyl-D-aspartic acid receptor 2AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50426005(CHEMBL2314933)
Affinity DataIC50: 231nMAssay Description:Inhibition of rat GluN1/2A receptor expressed in Xenopus laevis oocyte assessed as glutamate and glycine-induced current at holding potentials from -...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50425988(CHEMBL2314712)
Affinity DataIC50: 256nMAssay Description:Inhibition of rat GluN1/2A receptor expressed in Xenopus laevis oocyte assessed as glutamate and glycine-induced current at holding potentials from -...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50583023(CHEMBL5081203)
Affinity DataEC50:  260nMAssay Description:Agonist activity at rat GluN1/GluN2A NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50220152(2-(Amino-carboxy-methyl)-cyclopropanecarboxylic ac...)
Affinity DataEC50:  262nMAssay Description:Agonist activity at rat recombinant wild type GluN1/GluN2A receptor expressed in Xenopus laevis oocytes by two electrode voltage clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50432711(CHEMBL2348224)
Affinity DataEC50:  277nMAssay Description:Agonist activity at rat recombinant wild type GluN1/GluN2A receptor expressed in Xenopus laevis oocytes by two electrode voltage clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50004897(2-Amino-5-phosphono-pentanoic acid(R-AP5) | DL-2-a...)
Affinity DataKi:  280nMAssay Description:Inhibitory constant against (S)-glutamate and glycine evoked currents mediated by N-methyl-D-aspartate glutamate receptor NR1a/NR2A expressed in Xeno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlutamate receptor ionotropic, NMDA 2A(Rat)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50017229((S)-2-amino-5-phosphonopentanoic acid | (S)-2-Amin...)
Affinity DataIC50: 290nMAssay Description:Inhibition of [3H]CPP binding to rat N-methyl-D-aspartic acid receptor 2AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50164549((2R,3S)-1-(7-Bromo-phenanthrene-2-carbonyl)-pipera...)
Affinity DataKi:  320nMAssay Description:Antagonist activity at rat recombinant GluN1/GluN2A receptor expressed in Xenopus laevis oocytes assessed as inhibition of glutamate-induced response...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50164549((2R,3S)-1-(7-Bromo-phenanthrene-2-carbonyl)-pipera...)
Affinity DataKi:  320nMAssay Description:Inhibitory constant against (S)-glutamate and glycine evoked currents mediated by N-methyl-D-aspartate glutamate receptor NR1a/NR2A expressed in Xeno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50454188(CHEMBL4218368)
Affinity DataIC50: 379nMAssay Description:Antagonist activity at rat brain GluN1/GluN2A receptor expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induced channe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50018846(CHEMBL3286871)
Affinity DataIC50: 387nMAssay Description:Inhibition of rat recombinant GluN1/2A expressed in Xenopus oocytes assessed as inhibition of glutamate/glycine-evoked channel current at holding pot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM81977(CB3371309 | CAS_79055-68-8 | D-APV | D-AP5)
Affinity DataKi:  390nMAssay Description:Antagonist activity at recombinant rat GluN1a/GluN2A expressed in Xenopus laevis oocytes assessed as inhibition of glycine/glutamate-mediated current...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlutamate receptor ionotropic, NMDA 1/2A(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50017226(2-Amino-7-phosphono-heptanoic acid | CHEMBL302783 ...)
Affinity DataKi:  490nMAssay Description:Inhibitory constant against (S)-glutamate and glycine evoked currents mediated by N-methyl-D-aspartate glutamate receptor NR1a/NR2A expressed in Xeno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50236939(CHEMBL2333945)
Affinity DataIC50: 512nMAssay Description:Antagonist activity at rat GluN1A/GluN2A receptor expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induced channel cur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlutamate receptor ionotropic, NMDA 1/2A(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50164540((2R,3S)-1-(Phenanthrene-2-carbonyl)-piperazine-2,3...)
Affinity DataKi:  550nMAssay Description:Inhibitory constant against (S)-glutamate and glycine evoked currents mediated by N-methyl-D-aspartate glutamate receptor NR1a/NR2A expressed in Xeno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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