Affinity DataEC50: 1.5nMAssay Description:Inhibition of DNA topoisomerase 1 in mouse P388/S cells assessed as formation of topoisomerase 1-DNA complex by proteinase K/SDS methodMore data for this Ligand-Target Pair
Affinity DataEC50: 23nMAssay Description:Inhibition of DNA topoisomerase 1 in mouse P388/S cells assessed as formation of topoisomerase 1-DNA complex by proteinase K/SDS methodMore data for this Ligand-Target Pair
Affinity DataEC50: 24nMAssay Description:Inhibition of DNA topoisomerase 1 in mouse P388/S cells assessed as formation of topoisomerase 1-DNA complex by proteinase K/SDS methodMore data for this Ligand-Target Pair
Affinity DataEC50: 73nMAssay Description:Inhibition of DNA topoisomerase 1 in mouse P388/S cells assessed as formation of topoisomerase 1-DNA complex by proteinase K/SDS methodMore data for this Ligand-Target Pair
Affinity DataEC50: 80nMAssay Description:Inhibition of DNA topoisomerase 1 in mouse P388/S cells assessed as formation of topoisomerase 1-DNA complex by proteinase K/SDS methodMore data for this Ligand-Target Pair
Affinity DataEC50: 90nMAssay Description:Inhibition of DNA topoisomerase 1 in mouse P388/S cells assessed as formation of topoisomerase 1-DNA complex by proteinase K/SDS methodMore data for this Ligand-Target Pair
Affinity DataEC50: 100nMAssay Description:Inhibition of DNA topoisomerase 1 in mouse P388/S cells assessed as formation of topoisomerase 1-DNA complex by proteinase K/SDS methodMore data for this Ligand-Target Pair
Affinity DataEC50: 120nMAssay Description:Inhibition of DNA topoisomerase 1 in mouse P388/S cells assessed as formation of topoisomerase 1-DNA complex by proteinase K/SDS methodMore data for this Ligand-Target Pair
Affinity DataEC50: 120nMAssay Description:Inhibition of DNA topoisomerase 1 in mouse P388/S cells assessed as formation of topoisomerase 1-DNA complex by proteinase K/SDS methodMore data for this Ligand-Target Pair
Affinity DataEC50: 130nMAssay Description:Inhibition of DNA topoisomerase 1 in mouse P388/S cells assessed as formation of topoisomerase 1-DNA complex by proteinase K/SDS methodMore data for this Ligand-Target Pair
Affinity DataEC50: 130nMAssay Description:Inhibition of DNA topoisomerase 1 in mouse P388/S cells assessed as formation of topoisomerase 1-DNA complex by proteinase K/SDS methodMore data for this Ligand-Target Pair
Affinity DataEC50: 160nMAssay Description:Inhibition of DNA topoisomerase 1 in mouse P388/S cells assessed as formation of topoisomerase 1-DNA complex by proteinase K/SDS methodMore data for this Ligand-Target Pair
Affinity DataEC50: 180nMAssay Description:Inhibition of DNA topoisomerase 1 in mouse P388/S cells assessed as formation of topoisomerase 1-DNA complex by proteinase K/SDS methodMore data for this Ligand-Target Pair
Affinity DataEC50: 210nMAssay Description:Inhibition of DNA topoisomerase 1 in mouse P388/S cells assessed as formation of topoisomerase 1-DNA complex by proteinase K/SDS methodMore data for this Ligand-Target Pair
Affinity DataEC50: 220nMAssay Description:Inhibition of DNA topoisomerase 1 in mouse P388/S cells assessed as formation of topoisomerase 1-DNA complex by proteinase K/SDS methodMore data for this Ligand-Target Pair
Affinity DataEC50: 400nMAssay Description:Inhibition of DNA topoisomerase 1 in mouse P388/S cells assessed as formation of topoisomerase 1-DNA complex by proteinase K/SDS methodMore data for this Ligand-Target Pair
Affinity DataEC50: 420nMAssay Description:Inhibition of DNA topoisomerase 1 in mouse P388/S cells assessed as formation of topoisomerase 1-DNA complex by proteinase K/SDS methodMore data for this Ligand-Target Pair
Affinity DataEC50: 470nMAssay Description:Inhibition of DNA topoisomerase 1 in mouse P388/S cells assessed as formation of topoisomerase 1-DNA complex by proteinase K/SDS methodMore data for this Ligand-Target Pair
Affinity DataEC50: 600nMAssay Description:Inhibition of DNA topoisomerase 1 in mouse P388/S cells assessed as formation of topoisomerase 1-DNA complex by proteinase K/SDS methodMore data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Inhibition of topoisomerase 1 extracted from mouse EAC cells assessed as inhibition of Escherichia coli pBR322 relaxationMore data for this Ligand-Target Pair
Affinity DataEC50: 800nMAssay Description:Inhibition of DNA topoisomerase 1 in mouse P388/S cells assessed as formation of topoisomerase 1-DNA complex by proteinase K/SDS methodMore data for this Ligand-Target Pair
Affinity DataEC50: 1.70E+3nMAssay Description:Inhibition of DNA topoisomerase 1 in mouse P388/S cells assessed as formation of topoisomerase 1-DNA complex by proteinase K/SDS methodMore data for this Ligand-Target Pair
Affinity DataEC50: 1.80E+3nMAssay Description:Inhibition of DNA topoisomerase 1 in mouse P388/S cells assessed as formation of topoisomerase 1-DNA complex by proteinase K/SDS methodMore data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:Average concentration to cause 50% inhibition of topo 1 using the cleavable complex assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Average concentration to cause 50% inhibition of topo 1 using the cleavable complex assayMore data for this Ligand-Target Pair
Affinity DataEC50: 6.00E+3nMAssay Description:Inhibition of DNA topoisomerase 1 in mouse P388/S cells assessed as formation of topoisomerase 1-DNA complex by proteinase K/SDS methodMore data for this Ligand-Target Pair
Affinity DataEC50: 6.50E+3nMAssay Description:Inhibition of DNA topoisomerase 1 in mouse P388/S cells assessed as formation of topoisomerase 1-DNA complex by proteinase K/SDS methodMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of DNA topoisomerase 1 in mouse P388/S cells assessed as formation of topoisomerase 1-DNA complex by proteinase K/SDS methodMore data for this Ligand-Target Pair
Affinity DataEC50: 1.00E+4nMAssay Description:Inhibition of DNA topoisomerase 1 in mouse P388/S cells assessed as formation of topoisomerase 1-DNA complex by proteinase K/SDS methodMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of DNA topoisomerase 1 in mouse P388/S cells assessed as formation of topoisomerase 1-DNA complex by proteinase K/SDS methodMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of DNA topoisomerase 1 in mouse P388/S cells assessed as formation of topoisomerase 1-DNA complex by proteinase K/SDS methodMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of DNA topoisomerase 1 in mouse P388/S cells assessed as formation of topoisomerase 1-DNA complex by proteinase K/SDS methodMore data for this Ligand-Target Pair
Affinity DataEC50: 1.00E+4nMAssay Description:Inhibition of DNA topoisomerase 1 in mouse P388/S cells assessed as formation of topoisomerase 1-DNA complex by proteinase K/SDS methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+4nMAssay Description:Average concentration to cause 50% inhibition of topo 1 using the cleavable complex assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition topoisomerase 1 in mouse NIH/3T3 cells assessed as conversion of supercoiled pBR322 DNA to relaxed formMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+4nMAssay Description:Average concentration to cause 50% inhibition of topo 1 using the cleavable complex assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Average concentration to cause 50% inhibition of topo 1 using the cleavable complex assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+4nMAssay Description:Average concentration to cause 50% inhibition of topo 1 using the cleavable complex assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+4nMAssay Description:Average concentration to cause 50% inhibition of topo 1 using the cleavable complex assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.10E+4nMAssay Description:Average concentration to cause 50% inhibition of topo 1 using the cleavable complex assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.70E+4nMAssay Description:Inhibition topoisomerase 1 in mouse NIH/3T3 cells assessed as conversion of supercoiled pBR322 DNA to relaxed formMore data for this Ligand-Target Pair
Affinity DataIC50: 6.30E+4nMAssay Description:In vitro inhibitory activity against topoisomerase I (Topo I) by using relaxation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.02E+5nMAssay Description:In vitro inhibitory activity against topoisomerase I (Topo I) by using relaxation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.33E+5nMAssay Description:Average concentration to cause 50% inhibition of topo 1 using the cleavable complex assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.72E+5nMAssay Description:In vitro inhibitory activity against topoisomerase I (Topo I) by using relaxation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition topoisomerase 1 in mouse NIH/3T3 cells assessed as conversion of supercoiled pBR322 DNA to relaxed formMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+5nMAssay Description:In vitro inhibitory activity against topoisomerase I (Topo I) by using relaxation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+5nMAssay Description:In vitro inhibitory activity against topoisomerase I (Topo I) by using relaxation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibition topoisomerase 1 in mouse NIH/3T3 cells assessed as conversion of supercoiled pBR322 DNA to relaxed formMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+6nMAssay Description:Average concentration to cause 50% inhibition of topo 1 using the cleavable complex assayMore data for this Ligand-Target Pair
