Compile Data Set for Download or QSAR
Report error Found 83 of affinity data for UniProtKB/TrEMBL: Q99489
TargetD-aspartate oxidase(Human)
Pfizer

LigandChemical structure of BindingDB Monomer ID 31148BDBM31148(3-hydroxyquinolin-2(1H)-one, 2 | US9701638, 1)
Affinity DataIC50: 855nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-aspartate oxidase(Human)
Pfizer

LigandChemical structure of BindingDB Monomer ID 50427221BDBM50427221(5-Aminonicotinic Acid | CHEMBL1491941)
Affinity DataKi:  3.80E+3nMAssay Description:Binding affinity to human recombinant DDOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2016
Entry Details Article
PubMed
TargetD-aspartate oxidase(Human)
Pfizer

LigandChemical structure of BindingDB Monomer ID 31149BDBM31149(3-hydroxyquinolin-2(1H)-one, 3)
Affinity DataIC50: 4.62E+3nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-aspartate oxidase(Human)
Pfizer

LigandChemical structure of BindingDB Monomer ID 31147BDBM31147(4H-furo[3,2-b]pyrrole-5-carboxylic acid | CHEMBL49...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human DDOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD-aspartate oxidase(Human)
Pfizer

LigandChemical structure of BindingDB Monomer ID 23174BDBM23174(CHEMBL445990 | 6-chloro-1,2-benzoxazol-3-ol | 6-ch...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human DDOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD-aspartate oxidase(Human)
Pfizer

LigandChemical structure of BindingDB Monomer ID 50260722BDBM50260722(4-(4-chlorophenethyl)-1H-pyrrole-2-carboxylic acid...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human DDOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD-aspartate oxidase(Human)
Pfizer

LigandChemical structure of BindingDB Monomer ID 50260721BDBM50260721(4,5-dichlorofuran-2-carboxylic acid | CHEMBL511101)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human DDOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD-aspartate oxidase(Human)
Pfizer

LigandChemical structure of BindingDB Monomer ID 50004955BDBM50004955(Indol-2-carboxylic acid | CHEMBL278390 | Indole-2-...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human DDOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD-aspartate oxidase(Human)
Pfizer

LigandChemical structure of BindingDB Monomer ID 31164BDBM31164(naphthyridinone analog.,18)
Affinity DataIC50: 7.64E+3nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-aspartate oxidase(Human)
Pfizer

LigandChemical structure of BindingDB Monomer ID 31151BDBM31151(3-hydroxyquinolin-2(1H)-one, 5)
Affinity DataIC50: 8.88E+3nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-aspartate oxidase(Human)
Pfizer

LigandChemical structure of BindingDB Monomer ID 31173BDBM31173(naphthyridinone analog., 27)
Affinity DataIC50: 1.45E+4nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-aspartate oxidase(Human)
Pfizer

LigandChemical structure of BindingDB Monomer ID 50121995BDBM50121995(CHEMBL3617316)
Affinity DataKi:  1.51E+4nMAssay Description:Binding affinity to human recombinant DDOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2016
Entry Details Article
PubMed
TargetD-aspartate oxidase(Human)
Pfizer

LigandChemical structure of BindingDB Monomer ID 31147BDBM31147(4H-furo[3,2-b]pyrrole-5-carboxylic acid | CHEMBL49...)
Affinity DataIC50: 1.95E+4nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-aspartate oxidase(Human)
Pfizer

LigandChemical structure of BindingDB Monomer ID 31158BDBM31158(3-hydroxyquinolin-2(1H)-one, 12)
Affinity DataIC50: 2.15E+4nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-aspartate oxidase(Human)
Pfizer

LigandChemical structure of BindingDB Monomer ID 50427221BDBM50427221(5-Aminonicotinic Acid | CHEMBL1491941)
Affinity DataIC50: 2.19E+4nMAssay Description:Inhibition of human recombinant DDO expressed in Escherichia coli BL21(DE3) using D-Asp and D-Ala assessed as 2-oxo acid production after 10 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2016
Entry Details Article
PubMed
TargetD-aspartate oxidase(Human)
Pfizer

LigandChemical structure of BindingDB Monomer ID 31150BDBM31150(3-hydroxyquinolin-2(1H)-one, 4)
Affinity DataIC50: 2.24E+4nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-aspartate oxidase(Human)
Pfizer

LigandChemical structure of BindingDB Monomer ID 31157BDBM31157(3-hydroxyquinolin-2(1H)-one, 11)
Affinity DataIC50: 3.16E+4nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-aspartate oxidase(Human)
Pfizer

LigandChemical structure of BindingDB Monomer ID 31169BDBM31169(3-hydroxyquinolin-2(1H)-one, 23 | US9701638, 14)
Affinity DataIC50: 3.23E+4nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-aspartate oxidase(Human)
Pfizer

LigandChemical structure of BindingDB Monomer ID 31165BDBM31165(naphthyridinone analog.,19)
Affinity DataIC50: 3.60E+4nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-aspartate oxidase(Human)
Pfizer

LigandChemical structure of BindingDB Monomer ID 31172BDBM31172(3-hydroxyquinolin-2(1H)-one, 26)
Affinity DataIC50: 4.32E+4nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-aspartate oxidase(Human)
Pfizer

LigandChemical structure of BindingDB Monomer ID 31153BDBM31153(3-hydroxyquinolin-2(1H)-one, 7)
Affinity DataIC50: 4.34E+4nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-aspartate oxidase(Human)
Pfizer

LigandChemical structure of BindingDB Monomer ID 31163BDBM31163(3-hydroxyquinolin-2(1H)-one, 17)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-aspartate oxidase(Human)
Pfizer

LigandChemical structure of BindingDB Monomer ID 31166BDBM31166(naphthyridinone analog.,20)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-aspartate oxidase(Human)
Pfizer

LigandChemical structure of BindingDB Monomer ID 31167BDBM31167(naphthyridinone analog.,21)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-aspartate oxidase(Human)
Pfizer

LigandChemical structure of BindingDB Monomer ID 31168BDBM31168(pyridopyrazinone, 22)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-aspartate oxidase(Human)
Pfizer

LigandChemical structure of BindingDB Monomer ID 31154BDBM31154(3-hydroxyquinolin-2(1H)-one, 8)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-aspartate oxidase(Human)
Pfizer

LigandChemical structure of BindingDB Monomer ID 31155BDBM31155(3-hydroxyquinolin-2(1H)-one, 9)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-aspartate oxidase(Human)
Pfizer

LigandChemical structure of BindingDB Monomer ID 31160BDBM31160(3-hydroxyquinolin-2(1H)-one, 14)
Affinity DataIC50: 5.46E+4nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-aspartate oxidase(Human)
Pfizer

LigandChemical structure of BindingDB Monomer ID 31161BDBM31161(3-hydroxyquinolin-2(1H)-one, 15)
Affinity DataIC50: 6.19E+4nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-aspartate oxidase(Human)
Pfizer

LigandChemical structure of BindingDB Monomer ID 31152BDBM31152(3-hydroxyquinolin-2(1H)-one, 6)
Affinity DataIC50: 6.40E+4nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-aspartate oxidase(Human)
Pfizer

LigandChemical structure of BindingDB Monomer ID 50121995BDBM50121995(CHEMBL3617316)
Affinity DataIC50: 8.71E+4nMAssay Description:Inhibition of human recombinant DDO expressed in Escherichia coli BL21(DE3) using D-Asp and D-Ala assessed as 2-oxo acid production after 10 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2016
Entry Details Article
PubMed
TargetD-aspartate oxidase(Human)
Pfizer

LigandChemical structure of BindingDB Monomer ID 31147BDBM31147(4H-furo[3,2-b]pyrrole-5-carboxylic acid | CHEMBL49...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant N-terminal His-tagged DDO expressed in Escherichia coli BL21(DE3) using D-aspartate as substrate by colorimetric assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetD-aspartate oxidase(Human)
Pfizer

LigandChemical structure of BindingDB Monomer ID 50121996BDBM50121996(CHEMBL3617326)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant DDO expressed in Escherichia coli BL21(DE3) using D-Asp and D-Ala assessed as 2-oxo acid production after 10 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2016
Entry Details Article
PubMed
TargetD-aspartate oxidase(Human)
Pfizer

LigandChemical structure of BindingDB Monomer ID 50121998BDBM50121998(CHEMBL3322866)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant DDO expressed in Escherichia coli BL21(DE3) using D-Asp and D-Ala assessed as 2-oxo acid production after 10 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2016
Entry Details Article
PubMed
TargetD-aspartate oxidase(Human)
Pfizer

LigandChemical structure of BindingDB Monomer ID 50121997BDBM50121997(CHEMBL3322863)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant DDO expressed in Escherichia coli BL21(DE3) using D-Asp and D-Ala assessed as 2-oxo acid production after 10 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2016
Entry Details Article
PubMed
TargetD-aspartate oxidase(Human)
Pfizer

LigandChemical structure of BindingDB Monomer ID 50122001BDBM50122001(CHEMBL3617320)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant DDO expressed in Escherichia coli BL21(DE3) using D-Asp and D-Ala assessed as 2-oxo acid production after 10 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2016
Entry Details Article
PubMed
TargetD-aspartate oxidase(Human)
Pfizer

LigandChemical structure of BindingDB Monomer ID 14673BDBM14673(propanedioic acid | Fragment 3 | Malonic Acid)
Affinity DataKi:  1.53E+5nMAssay Description:Binding affinity to human recombinant DDOMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2016
Entry Details Article
PubMed
TargetD-aspartate oxidase(Human)
Pfizer

LigandChemical structure of BindingDB Monomer ID 31156BDBM31156(3-hydroxyquinolin-2(1H)-one, 10)
Affinity DataIC50: 2.06E+5nMAssay Description:Inhibitory effect of compounds was determined in a cell free fluorescence assay. The H2O2 generated from the degradation of D-serine was linked to ox...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2009
Entry Details Article
PubMed
TargetD-aspartate oxidase(Human)
Pfizer

LigandChemical structure of BindingDB Monomer ID 14673BDBM14673(propanedioic acid | Fragment 3 | Malonic Acid)
Affinity DataIC50: 8.79E+5nMAssay Description:Inhibition of human recombinant DDO expressed in Escherichia coli BL21(DE3) using D-Asp and D-Ala assessed as 2-oxo acid production after 10 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2016
Entry Details Article
PubMed
TargetD-aspartate oxidase(Human)
Pfizer

LigandChemical structure of BindingDB Monomer ID 50122008BDBM50122008(CHEMBL3617314)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human recombinant DDO expressed in Escherichia coli BL21(DE3) using D-Asp and D-Ala assessed as 2-oxo acid production after 10 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2016
Entry Details Article
PubMed
TargetD-aspartate oxidase(Human)
Pfizer

LigandChemical structure of BindingDB Monomer ID 50122018BDBM50122018(CHEMBL1529836)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human recombinant DDO expressed in Escherichia coli BL21(DE3) using D-Asp and D-Ala assessed as 2-oxo acid production after 10 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2016
Entry Details Article
PubMed
TargetD-aspartate oxidase(Human)
Pfizer

LigandChemical structure of BindingDB Monomer ID 50122000BDBM50122000(CHEBI:68572 | CHEMBL3322868)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human recombinant DDO expressed in Escherichia coli BL21(DE3) using D-Asp and D-Ala assessed as 2-oxo acid production after 10 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2016
Entry Details Article
PubMed
TargetD-aspartate oxidase(Human)
Pfizer

LigandChemical structure of BindingDB Monomer ID 50122003BDBM50122003(CHEMBL3617319)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human recombinant DDO expressed in Escherichia coli BL21(DE3) using D-Asp and D-Ala assessed as 2-oxo acid production after 10 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2016
Entry Details Article
PubMed
TargetD-aspartate oxidase(Human)
Pfizer

LigandChemical structure of BindingDB Monomer ID 14673BDBM14673(propanedioic acid | Fragment 3 | Malonic Acid)
Affinity DataIC50: 1.36E+6nMAssay Description:Inhibition of human recombinant N-terminal His-tagged DDO expressed in Escherichia coli BL21(DE3) using D-aspartate as substrate by colorimetric assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetD-aspartate oxidase(Human)
Pfizer

LigandChemical structure of BindingDB Monomer ID 50052793BDBM50052793(CHEBI:68583 | CHEMBL3322864)
Affinity DataIC50: 2.36E+6nMAssay Description:Inhibition of human recombinant DDO expressed in Escherichia coli BL21(DE3) using D-Asp and D-Ala assessed as 2-oxo acid production after 10 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2016
Entry Details Article
PubMed
TargetD-aspartate oxidase(Human)
Pfizer

LigandChemical structure of BindingDB Monomer ID 23515BDBM23515(pyridine-3-carboxylic acid | CHEMBL573 | [5, 6-3H]...)
Affinity DataIC50: 2.78E+6nMAssay Description:Inhibition of human recombinant DDO expressed in Escherichia coli BL21(DE3) using D-Asp and D-Ala assessed as 2-oxo acid production after 10 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2016
Entry Details Article
PubMed
TargetD-aspartate oxidase(Human)
Pfizer

LigandChemical structure of BindingDB Monomer ID 50391823BDBM50391823(CHEMBL2146902)
Affinity DataIC50: 3.35E+6nMAssay Description:Inhibition of human recombinant DDO expressed in Escherichia coli BL21(DE3) using D-Asp and D-Ala assessed as 2-oxo acid production after 10 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2016
Entry Details Article
PubMed
TargetD-aspartate oxidase(Human)
Pfizer

LigandChemical structure of BindingDB Monomer ID 50121999BDBM50121999(CHEMBL1588120)
Affinity DataIC50: 3.54E+6nMAssay Description:Inhibition of human recombinant DDO expressed in Escherichia coli BL21(DE3) using D-Asp and D-Ala assessed as 2-oxo acid production after 10 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2016
Entry Details Article
PubMed
TargetD-aspartate oxidase(Human)
Pfizer

LigandChemical structure of BindingDB Monomer ID 50427212BDBM50427212((2S,3R)-2,3-Dihydroxysuccinic Acid | Meso-Tartrate...)
Affinity DataIC50: 3.92E+6nMAssay Description:Inhibition of human recombinant N-terminal His-tagged DDO expressed in Escherichia coli BL21(DE3) using D-aspartate as substrate by colorimetric assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetD-aspartate oxidase(Human)
Pfizer

LigandChemical structure of BindingDB Monomer ID 50122007BDBM50122007(CHEMBL3617315)
Affinity DataIC50: 4.25E+6nMAssay Description:Inhibition of human recombinant DDO expressed in Escherichia coli BL21(DE3) using D-Asp and D-Ala assessed as 2-oxo acid production after 10 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2016
Entry Details Article
PubMed
Displayed 1 to 50 (of 83 total ) | Next | Last >>
Jump to: