Compile Data Set for Download or QSAR
Report error Found 19 of affinity data for UniProtKB/TrEMBL: Q9EQU3
TargetToll-like receptor 9(Mouse)
Princ

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50543465BDBM50543465(CHEMBL4636498)
Affinity DataEC50:  25nMAssay Description:Invivo antagonist activity at TLR9 in po dosed C57BL/6 mouse assessed as reduction of CpG-ODN-1585-induced IL-6 production pretreated for 30 mins fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetToll-like receptor 9(Mouse)
Princ

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50560353BDBM50560353(CHEMBL4792072)
Affinity DataIC50: 460nMAssay Description:Antagonist activity at TLR9 in mouse splenocytes assessed as inhibition of CpG1585-induced IL6 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetToll-like receptor 9(Mouse)
Princ

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50543465BDBM50543465(CHEMBL4636498)
Affinity DataIC50: 510nMAssay Description:Antagonist activity at TLR9 in mouse whole blood cells assessed as inhibition of ODN-2216 induced IL-6 production by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetToll-like receptor 9(Mouse)
Princ

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50560354BDBM50560354(CHEMBL4740820)
Affinity DataIC50: 800nMAssay Description:Antagonist activity at TLR9 in mouse splenocytes assessed as inhibition of CpG1585-induced IL6 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetToll-like receptor 9(Mouse)
Princ

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50560351BDBM50560351(CHEMBL4748638)
Affinity DataIC50: 840nMAssay Description:Antagonist activity at TLR9 in mouse splenocytes assessed as inhibition of CpG1585-induced IL6 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetToll-like receptor 9(Mouse)
Princ

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50627976BDBM50627976(CHEMBL5417170)
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at TLR9 in mouse Splenocyte assessed as reduction in IFN-alpha level measured after 20 hrs by Spectramax M5 methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetToll-like receptor 9(Mouse)
Princ

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50560349BDBM50560349(CHEMBL4782200)
Affinity DataIC50: 1.20E+3nMAssay Description:Antagonist activity at TLR9 in mouse splenocytes assessed as inhibition of CpG1585-induced IL6 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetToll-like receptor 9(Mouse)
Princ

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50543137BDBM50543137(CHEMBL4634860)
Affinity DataIC50: 1.20E+3nMAssay Description:Antagonist activity at TLR9 in mouse splenocytes assessed as inhibition of CpG1585-induced IL6 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetToll-like receptor 9(Mouse)
Princ

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50560348BDBM50560348(CHEMBL4796453)
Affinity DataIC50: 1.20E+3nMAssay Description:Antagonist activity at TLR9 in mouse splenocytes assessed as inhibition of CpG1585-induced IL6 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetToll-like receptor 9(Mouse)
Princ

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50560357BDBM50560357(CHEMBL4761527)
Affinity DataIC50: 1.20E+3nMAssay Description:Antagonist activity at TLR9 in mouse splenocytes assessed as inhibition of CpG1585-induced IL6 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetToll-like receptor 9(Mouse)
Princ

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50560356BDBM50560356(CHEMBL4755173)
Affinity DataIC50: 1.30E+3nMAssay Description:Antagonist activity at TLR9 in mouse splenocytes assessed as inhibition of CpG1585-induced IL6 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetToll-like receptor 9(Mouse)
Princ

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50560350BDBM50560350(CHEMBL4783510)
Affinity DataIC50: 1.90E+3nMAssay Description:Antagonist activity at TLR9 in mouse splenocytes assessed as inhibition of CpG1585-induced IL6 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetToll-like receptor 9(Mouse)
Princ

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50560346BDBM50560346(CHEMBL4743698)
Affinity DataIC50: 2.00E+3nMAssay Description:Antagonist activity at TLR9 in mouse splenocytes assessed as inhibition of CpG1585-induced IL6 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetToll-like receptor 9(Mouse)
Princ

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50560347BDBM50560347(CHEMBL4776103)
Affinity DataIC50: 2.00E+3nMAssay Description:Antagonist activity at TLR9 in mouse splenocytes assessed as inhibition of CpG1585-induced IL6 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetToll-like receptor 9(Mouse)
Princ

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50560352BDBM50560352(CHEMBL4745239)
Affinity DataIC50: 2.80E+3nMAssay Description:Antagonist activity at TLR9 in mouse splenocytes assessed as inhibition of CpG1585-induced IL6 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetToll-like receptor 9(Mouse)
Princ

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21958BDBM21958(2-(2,6-dimethylpyridin-4-yl)-3-isopropyl-5-(piperi...)
Affinity DataIC50: 5.00E+3nMAssay Description:Antagonist activity at ODN-2216 stimulated TLR9 in mouse whole blood assessed as inhibition of IL-6 production by ELISA analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetToll-like receptor 9(Mouse)
Princ

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50543142BDBM50543142(CHEMBL4641633)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at TLR9 in mouse whole blood inhibition of DOTAP-ODN2216-induced IFNalpha production preincubated for 30 mins followed by DOTAP-O...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetToll-like receptor 9(Mouse)
Princ

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50627976BDBM50627976(CHEMBL5417170)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at TLR9 in mouse Whole blood cell assessed as reduction in IFN-alpha level measured after 20 hrs by AlphaLISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetToll-like receptor 9(Mouse)
Princ

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50560355BDBM50560355(CHEMBL4740968)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at TLR9 in mouse splenocytes assessed as inhibition of CpG1585-induced IL6 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed