PMID

Data

Article Title

Organization

Systemic optimization and structural evaluation of quinoline derivatives as transthyretin amyloidogenesis inhibitors.

Chungnam National University

A novel bis-furan scaffold for transthyretin stabilization and amyloid inhibition.

Universidade De Coimbra

Enthalpic Forces Correlate with the Selectivity of Transthyretin-Stabilizing Ligands in Human Plasma.

Ume£

Inhibitory activities of propolis and its promising component, caffeic acid phenethyl ester, against amyloidogenesis of human transthyretin.

University of Toyama

Synthesis and evaluation of transthyretin amyloidosis inhibitors containing carborane pharmacophores.

University of California

Chemoselective small molecules that covalently modify one lysine in a non-enzyme protein in plasma.

The Scripps Research Institute

Identification of a novel ligand binding motif in the transthyretin channel.

Universidade Federal Do Rio De Janeiro

Isatin derivatives, a novel class of transthyretin fibrillogenesis inhibitors.

Universitat De Barcelona

Design of mechanism-based inhibitors of transthyretin amyloidosis: studies with biphenyl ethers and new structural templates.

Institute of Sciences

Enhancing the Safety and Efficacy of PSMA-Based Small-Molecule Drug Conjugates by Linker Stabilization and Conjugation to Transthyretin Binding Ligand.

University of The Pacific

Synthesis and biological evaluation of quinolone derivatives as transthyretin amyloidogenesis inhibitors and fluorescence sensors.

Chungnam National University

Development of a Highly Potent Transthyretin Amyloidogenesis Inhibitor: Design, Synthesis, and Evaluation.

Universitat Aut£Noma De Barcelona

Identification of Transthyretin Tetramer Kinetic Stabilizers That Are Capable of Inhibiting the Retinol-Dependent Retinol Binding Protein 4-Transthyretin Interaction: Potential Novel Therapeutics for Macular Degeneration, Transthyretin Amyloidosis, and Their Common Age-Related Comorbidities.

Albany College of Pharmacy and Health Sciences

Enhancing the Pharmacokinetic Profile of Interleukin 2 through Site-Specific Conjugation to a Selective Small-Molecule Transthyretin Ligand.

University of The Pacific

Repositioning of the Anthelmintic Drugs Bithionol and Triclabendazole as Transthyretin Amyloidogenesis Inhibitors.

University of Toyama

Inhibitory activities of anthraquinone and xanthone derivatives against transthyretin amyloidogenesis.

University of Toyama

Transthyretin Amyloidogenesis Inhibitors: From Discovery to Current Developments.

University of Toyama

Discovery of Bispecific Antagonists of Retinol Binding Protein 4 That Stabilize Transthyretin Tetramers: Scaffolding Hopping, Optimization, and Preclinical Pharmacological Evaluation as a Potential Therapy for Two Common Age-Related Comorbidities.

Albany College of Pharmacy and Health Sciences

Crown Ethers as Transthyretin Amyloidogenesis Inhibitors.

University of Toyama

Calorimetric Studies of Binary and Ternary Molecular Interactions between Transthyretin, A? Peptides, and Small-Molecule Chaperones toward an Alternative Strategy for Alzheimer's Disease Drug Discovery.

Institut De Qu??Mica Avan£Ada De Catalunya (I.Q.A.C.-C.S.I.C.)

Enthalpy-Driven Stabilization of Transthyretin by AG10 Mimics a Naturally Occurring Genetic Variant That Protects from Transthyretin Amyloidosis.

University of The Pacific

Insights on the Interaction between Transthyretin and A? in Solution. A Saturation Transfer Difference (STD) NMR Analysis of the Role of Iododiflunisal.

Cic Biogune

Stilbene Boronic Acids Form a Covalent Bond with Human Transthyretin and Inhibit Its Aggregation.

University of Wisconsin-Madison

Carbonic anhydrase inhibitory properties of novel sulfonamide derivatives of aminoindanes and aminotetralins.

Atatürk University

Peripheral-type benzodiazepine receptors in human cerebral cortex, kidney, and colon.

Technion-Israel Institute of Technology

Carbonic anhydrase inhibitors: stacking with Phe131 determines active site binding region of inhibitors as exemplified by the X-ray crystal structure of a membrane-impermeant antitumor sulfonamide complexed with isozyme II.

Istituto Di Biostrutture E Bioimmagini-Cnr