PMID

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Article Title

Organization

Recent Progress in Histone Demethylase Inhibitors.

University of Oxford

Docking and Linking of Fragments To Discover Jumonji Histone Demethylase Inhibitors.

University of Oxford

8-Substituted Pyrido[3,4-d]pyrimidin-4(3H)-one Derivatives As Potent, Cell Permeable, KDM4 (JMJD2) and KDM5 (JARID1) Histone Lysine Demethylase Inhibitors.

The Institute of Cancer Research

Identification of the KDM2/7 histone lysine demethylase subfamily inhibitor and its antiproliferative activity.

Kyoto Prefectural University of Medicine

Quantitative analysis of histone demethylase probes using fluorescence polarization.

University of Colorado

Plant growth regulator daminozide is a selective inhibitor of human KDM2/7 histone demethylases.

University of Oxford

Lysine demethylases inhibitors.

Kyoto Prefectural University of Medicine

Structure-Based Design of Selective Fat Mass and Obesity Associated Protein (FTO) Inhibitors.

University of Oxford

Recent Advances with KDM4 Inhibitors and Potential Applications.

St. Jude Children'S Research Hospital

Drug discovery of histone lysine demethylases (KDMs) inhibitors (progress from 2018 to present).

Hangzhou Normal University

Small-Molecule Inhibitors of the MLL1 CXXC Domain, an Epigenetic Reader of DNA Methylation.

University of Virginia

First-in-Class Inhibitors of the Ribosomal Oxygenase MINA53.

University of Oxford

Design and Synthesis of Styrenylcyclopropylamine LSD1 Inhibitors.

Constellation Pharmaceuticals

Identification of novel lysine demethylase 5-selective inhibitors by inhibitor-based fragment merging strategy.

Kyoto Prefectural University of Medicine

C8-substituted pyrido[3,4-d]pyrimidin-4(3H)-ones: Studies towards the identification of potent, cell penetrant Jumonji C domain containing histone lysine demethylase 4 subfamily (KDM4) inhibitors, compound profiling in cell-based target engagement assays.

Institute of Cancer Research

Optimisation of a triazolopyridine based histone demethylase inhibitor yields a potent and selective KDM2A (FBXL11) inhibitor.

University of Oxford

Pan-histone demethylase inhibitors simultaneously targeting Jumonji C and lysine-specific demethylases display high anticancer activities.

Sapienza University of Rome

Structure-based design and discovery of potent and selective KDM5 inhibitors.

Celgene

In search of new a-glucosidase inhibitors: Imidazolylpyrazole derivatives.

University of The Punjab

Inhibition of protein kinase CK2 by anthraquinone-related compounds. A structural insight.

University of Padova