PMID

Data

Article Title

Organization

5-Lipoxygenase inhibitors suppress RANKL-induced osteoclast formation via NFATc1 expression.

Sookmyung Women'S University

5-lipoxygenase: properties, pharmacology, and the quinolinyl(bridged)aryl class of inhibitors.

Wyeth-Ayerst Research

Simple aromatic compounds containing propenone moiety show considerable dual COX/5-LOX inhibitory activities.

Yeungnam University

Bioassay-guided identification of an anti-inflammatory prenylated acylphloroglucinol from Melicope ptelefolia and molecular insights into its interaction with 5-lipoxygenase.

Universiti Putra Malaysia

Synthesis and evaluation of benzoxazole derivatives as 5-lipoxygenase inhibitors.

Ewha Womans University

Conformational analysis of 5-lipoxygenase inhibitors: role of the substituents in chiral recognition and on the active conformations of the (methoxyalkyl)thiazole and methoxytetrahydropyran series.

Astrazeneca

(Methoxyalkyl)thiazoles: a new series of potent, selective, and orally active 5-lipoxygenase inhibitors displaying high enantioselectivity.

Ici Pharmaceuticals Group