Compile Data Set for Download or QSAR
Report error Found 45 Enz. Inhib. hit(s) with all data for entry = 50006004
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mouse)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043670BDBM50043670(2-{(S)-1-[3-Fluoro-5-(naphthalen-2-ylmethoxy)-phen...)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of 5-lipoxygenase from mouse macrophageMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mouse)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043682BDBM50043682((R)-2-[3-Fluoro-5-(naphthalen-2-ylmethoxy)-phenyl]...)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of 5-lipoxygenase from mouse macrophageMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mouse)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043669BDBM50043669(6-[3-Fluoro-5-((S)-1-methoxy-1-thiazol-2-yl-propyl...)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of 5-lipoxygenase from mouse macrophageMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mouse)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043677BDBM50043677((S)-2-[3-Fluoro-5-(naphthalen-2-ylmethoxy)-phenyl]...)
Affinity DataIC50: 5nMAssay Description:Inhibition of 5-lipoxygenase from mouse macrophageMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mouse)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043666BDBM50043666((R)-2-[3-Fluoro-5-(1-methyl-2-oxo-1,2-dihydro-quin...)
Affinity DataIC50: 9.60nMAssay Description:Inhibition of 5-lipoxygenase from mouse macrophageMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mouse)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043678BDBM50043678((S)-2-[3-Fluoro-5-(1-methyl-2-oxo-1,2-dihydro-quin...)
Affinity DataIC50: 12nMAssay Description:Inhibition of 5-lipoxygenase from mouse macrophageMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50000829BDBM50000829(6-[3-Fluoro-5-(tetrahydro-pyran-4-yl)-phenoxymethy...)
Affinity DataIC50: 27nMAssay Description:Inhibition of 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mouse)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043676BDBM50043676(6-[3-Fluoro-5-((S)-1-methoxy-1-methoxymethyl-propy...)
Affinity DataIC50: 45nMAssay Description:Inhibition of 5-lipoxygenase from mouse macrophageMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mouse)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043671BDBM50043671(6-[3-Fluoro-5-((R)-1-methoxy-1-methoxymethyl-propy...)
Affinity DataIC50: 48nMAssay Description:Inhibition of 5-lipoxygenase from mouse macrophageMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50407160BDBM50407160(CHEMBL2092747)
Affinity DataIC50: 60nMAssay Description:Inhibition of 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043681BDBM50043681(4-[3-(1-Methyl-2-oxo-1,2-dihydro-quinolin-6-ylmeth...)
Affinity DataIC50: 70nMAssay Description:Inhibition of 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043676BDBM50043676(6-[3-Fluoro-5-((S)-1-methoxy-1-methoxymethyl-propy...)
Affinity DataIC50: 70nMAssay Description:Inhibitory concentration against 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043665BDBM50043665(6-[3-(4-Acetyl-tetrahydro-pyran-4-yl)-phenoxymethy...)
Affinity DataIC50: 100nMAssay Description:Inhibition of 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043666BDBM50043666((R)-2-[3-Fluoro-5-(1-methyl-2-oxo-1,2-dihydro-quin...)
Affinity DataIC50: 110nMAssay Description:Inhibitory concentration against 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043668BDBM50043668(6-[3-(4-Ethyl-tetrahydro-pyran-4-yl)-phenoxymethyl...)
Affinity DataIC50: 150nMAssay Description:Inhibition of 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043683BDBM50043683(6-[3-(4-Methoxymethyl-tetrahydro-pyran-4-yl)-pheno...)
Affinity DataIC50: 170nMAssay Description:Inhibition of 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mouse)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043672BDBM50043672(6-[3-Fluoro-5-((R)-1-methoxy-1-thiazol-2-yl-propyl...)
Affinity DataIC50: 201nMAssay Description:Inhibition of 5-lipoxygenase from mouse macrophageMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043682BDBM50043682((R)-2-[3-Fluoro-5-(naphthalen-2-ylmethoxy)-phenyl]...)
Affinity DataIC50: 220nMAssay Description:Inhibitory concentration against 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043677BDBM50043677((S)-2-[3-Fluoro-5-(naphthalen-2-ylmethoxy)-phenyl]...)
Affinity DataIC50: 330nMAssay Description:Inhibitory concentration against 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043678BDBM50043678((S)-2-[3-Fluoro-5-(1-methyl-2-oxo-1,2-dihydro-quin...)
Affinity DataIC50: 340nMAssay Description:Inhibitory concentration against 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50000857BDBM50000857(2-{1-Methoxy-1-[3-(naphthalen-2-ylmethoxy)-phenyl]...)
Affinity DataIC50: 400nMAssay Description:Inhibition of 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043669BDBM50043669(6-[3-Fluoro-5-((S)-1-methoxy-1-thiazol-2-yl-propyl...)
Affinity DataIC50: 410nMAssay Description:Inhibitory concentration against 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043664BDBM50043664(1-Methyl-6-[3-(4-methyl-tetrahydro-pyran-4-yl)-phe...)
Affinity DataIC50: 440nMAssay Description:Inhibition of 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043675BDBM50043675(5-[1-Methoxy-6-(naphthalen-2-ylmethoxy)-indan-1-yl...)
Affinity DataIC50: 500nMAssay Description:Inhibitory concentration against 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043667BDBM50043667(2-{(R)-1-Methoxy-1-[2-methyl-3-(naphthalen-2-ylmet...)
Affinity DataIC50: 510nMAssay Description:Inhibition of 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mouse)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043673BDBM50043673(2-{(R)-1-[3-Fluoro-5-(naphthalen-2-ylmethoxy)-phen...)
Affinity DataIC50: 513nMAssay Description:Inhibition of 5-lipoxygenase from mouse macrophageMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043671BDBM50043671(6-[3-Fluoro-5-((R)-1-methoxy-1-methoxymethyl-propy...)
Affinity DataIC50: 520nMAssay Description:Inhibitory concentration against 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007055BDBM50007055(CHEMBL20905 | 4-{1-Methoxy-1-[3-(naphthalen-2-ylme...)
Affinity DataIC50: 600nMAssay Description:Inhibition of 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007040BDBM50007040(CHEMBL20953 | 2-[1-Methoxy-6-(naphthalen-2-ylmetho...)
Affinity DataIC50: 700nMAssay Description:Inhibition of 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043670BDBM50043670(2-{(S)-1-[3-Fluoro-5-(naphthalen-2-ylmethoxy)-phen...)
Affinity DataIC50: 740nMAssay Description:Inhibition of 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043679BDBM50043679(6-[3-Fluoro-5-(4-hydroxy-tetrahydro-pyran-4-yl)-ph...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mouse)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043675BDBM50043675(5-[1-Methoxy-6-(naphthalen-2-ylmethoxy)-indan-1-yl...)
Affinity DataIC50: 1.25E+3nMAssay Description:Inhibition of 5-lipoxygenase from mouse macrophageMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Mouse)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007040BDBM50007040(CHEMBL20953 | 2-[1-Methoxy-6-(naphthalen-2-ylmetho...)
Affinity DataIC50: 1.25E+3nMAssay Description:Inhibitory concentration against 5-lipoxygenase from mouse macrophageMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50407159BDBM50407159(CHEMBL2092993)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043684BDBM50043684(6-[3-(4-Hydroxymethyl-tetrahydro-pyran-4-yl)-pheno...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043672BDBM50043672(6-[3-Fluoro-5-((R)-1-methoxy-1-thiazol-2-yl-propyl...)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibitory concentration against 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007054BDBM50007054(CHEMBL416735 | 5-{1-Methoxy-1-[3-(naphthalen-2-ylm...)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043680BDBM50043680(4-[3-(1-Methyl-2-oxo-1,2-dihydro-quinolin-6-ylmeth...)
Affinity DataIC50: 9.90E+3nMAssay Description:Inhibition of 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043673BDBM50043673(2-{(R)-1-[3-Fluoro-5-(naphthalen-2-ylmethoxy)-phen...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007046BDBM50007046(CHEMBL430908 | 2-(3-Methoxy-indan-5-yloxymethyl)-n...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043675BDBM50043675(5-[1-Methoxy-6-(naphthalen-2-ylmethoxy)-indan-1-yl...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibitory concentration against 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50000826BDBM50000826(CHEMBL21609 | 2-{1-Methoxy-1-[2-methyl-5-(naphthal...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007045BDBM50007045(CHEMBL277037 | 2-[1-Methoxy-4-(naphthalen-2-ylmeth...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007040BDBM50007040(CHEMBL20953 | 2-[1-Methoxy-6-(naphthalen-2-ylmetho...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007061BDBM50007061(CHEMBL433817 | 2-[6-(Naphthalen-2-ylmethoxy)-indan...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of 5-lipoxygenase from human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed