PMID

Data

Article Title

Organization

Discovery of a novel series of selective HCN1 blockers.

Johnson & Johnson Pharmaceutical Research & Development

Design, synthesis, and preliminary biological evaluation of new isoform-selective f-current blockers.

Laboratory of Design, Synthesis, and Study of Biologically Active Heterocycles (Heterobiolab)

SAGE-718: A First-in-Class

Sage Therapeutics

EC18 as a Tool To Understand the Role of HCN4 Channels in Mediating Hyperpolarization-Activated Current in Tissues.

University of Florence

Chemical synthesis and biological activity of novel brominated 7-deazaadenosine-3',5'-cyclic monophosphate derivatives.

University Hospital Jena

Neuroactive Steroids. 2. 3?-Hydroxy-3?-methyl-21-(4-cyano-1H-pyrazol-1'-yl)-19-nor-5?-pregnan-20-one (SAGE-217): A Clinical Next Generation Neuroactive Steroid Positive Allosteric Modulator of the (?-Aminobutyric Acid)

Sage Therapeutics

Discovery of N-(5-Fluoropyridin-2-yl)-6-methyl-4-(pyrimidin-5-yloxy)picolinamide (VU0424238): A Novel Negative Allosteric Modulator of Metabotropic Glutamate Receptor Subtype 5 Selected for Clinical Evaluation.

Vanderbilt University Institute of Imaging Science