13 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
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Piperidinyl thiazole isoxazolines: A new series of highly potent, slowly reversible FAAH inhibitors with analgesic properties.
E.I. Du Pont De Nemours
Use of ab initio calculations to predict the biological potency of carboxylesterase inhibitors.
University of California
Influence of sulfur oxidation state and steric bulk upon trifluoromethyl ketone (TFK) binding kinetics to carboxylesterases and fatty acid amide hydrolase (FAAH).
University of California
Synthesis and testing of trifluoromethyl-containing phosphonate-peptide conjugates as inhibitors of serine hydrolases.
Moscow State University
Synthesis of organophosphates with fluorine-containing leaving groups as serine esterase inhibitors with potential for Alzheimer disease therapeutics.
Institute of Physiologically Active Compounds Russian Academy of Sciences
Cathepsin A is the major hydrolase catalyzing the intracellular hydrolysis of the antiretroviral nucleotide phosphonoamidate prodrugs GS-7340 and GS-9131.
Gilead Sciences
Novel potent bifunctional carboxylesterase inhibitors based on a polyfluoroalkyl-2-imino-1,3-dione scaffold.
Institute of Physiologically Active Compounds Russian Academy of Sciences
Synthesis of 2-arylhydrazinylidene-3-oxo-4,4,4-trifluorobutanoic acids as new selective carboxylesterase inhibitors and radical scavengers.
Ural Branch of Russian Academy of Sciences
Synthesis, molecular docking and biological evaluation of N,N-disubstituted 2-aminothiazolines as a new class of butyrylcholinesterase and carboxylesterase inhibitors.
Institute of Physiologically Active Compounds Russian Academy of Sciences
Synthesis of new carboxylesterase inhibitors and evaluation of potency and water solubility.
University of California At Davis
Synthesis, molecular docking, and biological activity of 2-vinyl chromones: Toward selective butyrylcholinesterase inhibitors for potential Alzheimer's disease therapeutics.
Institute of Physiologically Active Compounds Russian Academy of Sciences
Synthesis, molecular docking, and biological activity of polyfluoroalkyl dihydroazolo[5,1-c][1,2,4]triazines as selective carboxylesterase inhibitors.
Urals Branch of Russian Academy of Sciences