26 articles for thisTarget
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Article Title
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Potent and selective non-cysteine-containing inhibitors of protein farnesyltransferase.
Abbott Laboratories
Structure-activity relationships of cysteine-lacking pentapeptide derivatives that inhibit ras farnesyltransferase.
Warner-Lambert
Pseudopeptide inhibitors of Ras farnesyl-protein transferase.
Merck Research Laboratories
Synthesis and evaluation of a novel series of farnesyl protein transferase inhibitors as non-peptidic CAAX tetrapeptide analogues.
Centre De Recherche Pierre Fabre
Synthesis and evaluation of hydroxyproline-derived isoprenyltransferase inhibitors.
Eisai Research Institute
Inhibition of farnesyl protein transferase by new farnesyl phosphonate derivatives of phenylalanine
TBA
Design and synthesis of o-trifluoromethylbiphenyl substituted 2-amino-nicotinonitriles as inhibitors of farnesyltransferase.
Abbott Laboratories
Synthesis and activity of 1-aryl-1'-imidazolyl methyl ethers as non-thiol farnesyltransferase inhibitors.
Abbott Laboratories
Design, synthesis, and activity of 4-quinolone and pyridone compounds as nonthiol-containing farnesyltransferase inhibitors.
Abbott Laboratories
Improvement of biological activity and proteolytic stability of peptides by coupling with a cyclic peptide.
Kyowa Hakko Kogyo
Discovery and structure-activity relationships of novel piperidine inhibitors of farnesyltransferase.
Pharmaceutical Research Institute
Discovery of potent imidazole and cyanophenyl containing farnesyltransferase inhibitors with improved oral bioavailability.
Abbott Laboratories
From pure FPP to mixed FPP and CAAX competitive inhibitors of farnesyl protein transferase.
Centre De Recherche Pierre Fabre
Novel and selective imidazole-containing biphenyl inhibitors of protein farnesyltransferase.
Abbott Laboratories
Development of tripeptidyl farnesyltransferase inhibitors.
Department of Chemistry and School of Molecular Science(Bk21)
Potent inhibitors of farnesyltransferase and geranylgeranyltransferase-I.
Merck Research Laboratories
Imidazole-containing diarylether and diarylsulfone inhibitors of farnesyl-protein transferase.
Merck Research Laboratories
Second-generation peptidomimetic inhibitors of protein farnesyltransferase demonstrating improved cellular potency and significant in vivo efficacy.
Abbott Laboratories
Aryl tetrahydropyridine inhibitors of farnesyltransferase: glycine, phenylalanine and histidine derivatives.
Abbott Laboratories
Design, synthesis, and activity of achiral analogs of 2-quinolones and indoles as non-thiol farnesyltransferase inhibitors.
Abbott Laboratories