Compile Data Set for Download or QSAR
maximum 50k data
Found 51 Enz. Inhib. hit(s) with all data for entry = 50035008
LigandPNGBDBM50059858((S)-2-((3Z,6E)-(2S,5S,8R)-8-Amino-2-benzyl-5-isopr...)
Affinity DataIC50:  1nMAssay Description:In vitro inhibitory activity against Geranylgeranyl transferase in the geranylgeranylation of H-ras-CAIL proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Bos taurus (bovine))
Eisai Research Institute

Curated by ChEMBL
LigandPNGBDBM50079813(2-[1-[5-amino-6-sulfanyl-(5R)-hexanoyl]-4-phenoxy-...)
Affinity DataIC50:  2nMAssay Description:Inhibitory concentration was evaluated against Farnesyltransferase in the farnesylation of H-ras proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50079803((S)-2-{[(2S,4S)-1-((E)-(2S,5R)-5-Amino-2-isopropyl...)
Affinity DataIC50:  11nMAssay Description:In vitro inhibitory activity against Geranylgeranyl transferase in the geranylgeranylation of H-ras-CAIL proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Bos taurus (bovine))
Eisai Research Institute

Curated by ChEMBL
LigandPNGBDBM50079810(2-[1-[5-amino-2-isopropyl-6-sulfanyl-(2S,3E,5R)-3-...)
Affinity DataIC50:  17nMAssay Description:Inhibitory concentration was evaluated against Farnesyltransferase in the farnesylation of H-ras proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Bos taurus (bovine))
Eisai Research Institute

Curated by ChEMBL
LigandPNGBDBM50079803((S)-2-{[(2S,4S)-1-((E)-(2S,5R)-5-Amino-2-isopropyl...)
Affinity DataIC50:  18nMAssay Description:Inhibitory concentration was evaluated against Farnesyltransferase in the farnesylation of H-ras proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Bos taurus (bovine))
Eisai Research Institute

Curated by ChEMBL
LigandPNGBDBM50079786(2-[1-[5-amino-6-sulfanyl-(5R)-hexyl]-4-phenoxy-(2S...)
Affinity DataIC50:  20nMAssay Description:Inhibitory concentration was evaluated against Farnesyltransferase in the farnesylation of H-ras proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Bos taurus (bovine))
Eisai Research Institute

Curated by ChEMBL
LigandPNGBDBM50079793(2-[1-[5-amino-6-sulfanyl-(E,5R)-3-hexenyl]-4-pheno...)
Affinity DataIC50:  20nMAssay Description:Inhibitory concentration was evaluated against Farnesyltransferase in the farnesylation of H-ras proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Bos taurus (bovine))
Eisai Research Institute

Curated by ChEMBL
LigandPNGBDBM50059858((S)-2-((3Z,6E)-(2S,5S,8R)-8-Amino-2-benzyl-5-isopr...)
Affinity DataIC50:  26nMAssay Description:Inhibitory concentration was evaluated against Farnesyltransferase in the farnesylation of H-ras proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Bos taurus (bovine))
Eisai Research Institute

Curated by ChEMBL
LigandPNGBDBM50079804(2-[1-[4-amino-5-sulfanyl-(E,4R)-2-pentenyl]-4-(4-p...)
Affinity DataIC50:  35nMAssay Description:Inhibitory concentration was evaluated against Farnesyltransferase in the farnesylation of H-ras proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50079787(CHEMBL303859 | methyl 2-[1-[5-amino-2-isopropyl-6-...)
Affinity DataIC50:  40nMAssay Description:Inhibitory concentration against Farnesyltransferase for Farnesylation of H-ras protein InNIH 3T3 cells transformed with activated H-rasMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Bos taurus (bovine))
Eisai Research Institute

Curated by ChEMBL
LigandPNGBDBM50079809((S)-2-{[(2S,4S)-1-((E)-(R)-4-Amino-5-mercapto-pent...)
Affinity DataIC50:  47nMAssay Description:Inhibitory concentration was evaluated against Farnesyltransferase in the farnesylation of H-ras proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50403711(CHEMBL2092855)
Affinity DataIC50:  53nMAssay Description:In vitro inhibitory activity against Geranylgeranyl transferase in the geranylgeranylation of H-ras-CAIL proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Bos taurus (bovine))
Eisai Research Institute

Curated by ChEMBL
LigandPNGBDBM50403711(CHEMBL2092855)
Affinity DataIC50:  57nMAssay Description:In vitro inhibitory activity against Geranylgeranyl transferase in the geranylgeranylation of H-ras-CAIL proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Bos taurus (bovine))
Eisai Research Institute

Curated by ChEMBL
LigandPNGBDBM50079811(2-[1-[4-amino-5-sulfanyl-(E,4R)-2-pentenyl]-4-(4-i...)
Affinity DataIC50:  82nMAssay Description:Inhibitory concentration was evaluated against Farnesyltransferase in the farnesylation of H-ras proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Bos taurus (bovine))
Eisai Research Institute

Curated by ChEMBL
LigandPNGBDBM50079792(2-[1-[4-amino-5-sulfanyl-(E,4R)-2-pentenyl]-4-(4-b...)
Affinity DataIC50:  87nMAssay Description:Inhibitory concentration was evaluated against Farnesyltransferase in the farnesylation of H-ras proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50079809((S)-2-{[(2S,4S)-1-((E)-(R)-4-Amino-5-mercapto-pent...)
Affinity DataIC50:  89nMAssay Description:In vitro inhibitory activity against Geranylgeranyl transferase in the geranylgeranylation of H-ras-CAIL proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50079813(2-[1-[5-amino-6-sulfanyl-(5R)-hexanoyl]-4-phenoxy-...)
Affinity DataIC50:  100nMAssay Description:In vitro inhibitory activity against Geranylgeranyl transferase in the geranylgeranylation of H-ras-CAIL proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Bos taurus (bovine))
Eisai Research Institute

Curated by ChEMBL
LigandPNGBDBM50216999(CHEMBL3349357)
Affinity DataIC50:  100nMAssay Description:Inhibitory concentration was evaluated against Farnesyltransferase in the farnesylation of H-ras proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50079794(2-[1-[4-amino-5-sulfanyl-(E,4R)-2-pentenyl]-4-(4-t...)
Affinity DataIC50:  110nMAssay Description:In vitro inhibitory activity against Geranylgeranyl transferase in the geranylgeranylation of H-ras-CAIL proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Bos taurus (bovine))
Eisai Research Institute

Curated by ChEMBL
LigandPNGBDBM50079794(2-[1-[4-amino-5-sulfanyl-(E,4R)-2-pentenyl]-4-(4-t...)
Affinity DataIC50:  110nMAssay Description:Inhibitory concentration was evaluated against Farnesyltransferase in the farnesylation of H-ras proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50079810(2-[1-[5-amino-2-isopropyl-6-sulfanyl-(2S,3E,5R)-3-...)
Affinity DataIC50:  150nMAssay Description:In vitro inhibitory activity against Geranylgeranyl transferase in the geranylgeranylation of H-ras-CAIL proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50079806(2-[1-[4-amino-5-sulfanyl-(E,4R)-2-pentenyl]-4-(2-p...)
Affinity DataIC50:  170nMAssay Description:Inhibitory concentration against Farnesyltransferase for Farnesylation of H-ras protein InNIH 3T3 cells transformed with activated H-rasMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50079792(2-[1-[4-amino-5-sulfanyl-(E,4R)-2-pentenyl]-4-(4-b...)
Affinity DataIC50:  180nMAssay Description:In vitro inhibitory activity against Geranylgeranyl transferase in the geranylgeranylation of H-ras-CAIL proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50216999(CHEMBL3349357)
Affinity DataIC50:  200nMAssay Description:Inhibitory concentration was evaluated against Farnesyltransferase in the farnesylation of H-ras proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Bos taurus (bovine))
Eisai Research Institute

Curated by ChEMBL
LigandPNGBDBM50079806(2-[1-[4-amino-5-sulfanyl-(E,4R)-2-pentenyl]-4-(2-p...)
Affinity DataIC50:  210nMAssay Description:Inhibitory concentration was evaluated against Farnesyltransferase in the farnesylation of H-ras proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50079811(2-[1-[4-amino-5-sulfanyl-(E,4R)-2-pentenyl]-4-(4-i...)
Affinity DataIC50:  210nMAssay Description:In vitro inhibitory activity against Geranylgeranyl transferase in the geranylgeranylation of H-ras-CAIL proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50079804(2-[1-[4-amino-5-sulfanyl-(E,4R)-2-pentenyl]-4-(4-p...)
Affinity DataIC50:  250nMAssay Description:In vitro inhibitory activity against Geranylgeranyl transferase in the geranylgeranylation of H-ras-CAIL proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50079805(CHEMBL302834 | methyl 2-[1-[5-amino-6-sulfanyl-(5R...)
Affinity DataIC50:  350nMAssay Description:Inhibitory concentration against Farnesyltransferase for Farnesylation of H-ras protein InNIH 3T3 cells transformed with activated H-rasMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50059858((S)-2-((3Z,6E)-(2S,5S,8R)-8-Amino-2-benzyl-5-isopr...)
Affinity DataIC50:  370nMAssay Description:Inhibitory concentration against Farnesyltransferase for Farnesylation of H-ras protein InNIH 3T3 cells transformed with activated H-rasMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Bos taurus (bovine))
Eisai Research Institute

Curated by ChEMBL
LigandPNGBDBM50366603(CHEMBL1793799 | CHEMBL3349310)
Affinity DataIC50:  450nMAssay Description:Inhibitory concentration was evaluated against Farnesyltransferase in the farnesylation of H-ras proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50079785(CHEMBL433102 | methyl 2-[1-[5-amino-6-sulfanyl-(E,...)
Affinity DataIC50:  490nMAssay Description:Inhibitory concentration against Farnesyltransferase for Farnesylation of H-ras protein InNIH 3T3 cells transformed with activated H-rasMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50079793(2-[1-[5-amino-6-sulfanyl-(E,5R)-3-hexenyl]-4-pheno...)
Affinity DataIC50:  570nMAssay Description:In vitro inhibitory activity against Geranylgeranyl transferase in the geranylgeranylation of H-ras-CAIL proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50079790((S)-2-{[(2S,4S)-1-((E)-(2S,5R)-5-Amino-2-isopropyl...)
Affinity DataIC50:  840nMAssay Description:Inhibitory concentration against Farnesyltransferase for Farnesylation of H-ras protein InNIH 3T3 cells transformed with activated H-rasMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50079800(CHEMBL303363 | methyl 2-[1-[5-amino-6-sulfanyl-(5R...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibitory concentration against Farnesyltransferase for Farnesylation of H-ras protein InNIH 3T3 cells transformed with activated H-rasMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50079802(CHEMBL302025 | methyl 2-[1-[4-amino-5-sulfanyl-(E,...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibitory concentration against Farnesyltransferase for Farnesylation of H-ras protein InNIH 3T3 cells transformed with activated H-rasMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50079791(CHEMBL304823 | methyl 2-[1-[4-amino-5-sulfanyl-(E,...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibitory concentration against Farnesyltransferase for Farnesylation of H-ras protein InNIH 3T3 cells transformed with activated H-rasMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Bos taurus (bovine))
Eisai Research Institute

Curated by ChEMBL
LigandPNGBDBM50403713(CHEMBL2092731)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibitory concentration was evaluated against Farnesyltransferase in the farnesylation of H-ras proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50079786(2-[1-[5-amino-6-sulfanyl-(5R)-hexyl]-4-phenoxy-(2S...)
Affinity DataIC50:  3.30E+3nMAssay Description:In vitro inhibitory activity against Geranylgeranyl transferase in the geranylgeranylation of H-ras-CAIL proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50079797(CHEMBL66788 | methyl 2-[1-[4-amino-5-sulfanyl-(E,4...)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibitory concentration against Farnesyltransferase for Farnesylation of H-ras protein InNIH 3T3 cells transformed with activated H-rasMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Bos taurus (bovine))
Eisai Research Institute

Curated by ChEMBL
LigandPNGBDBM50079812((S)-2-{[(2S,4R)-1-((E)-(R)-4-Amino-5-mercapto-pent...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibitory concentration was evaluated against Farnesyltransferase in the farnesylation of H-ras proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50403712(CHEMBL2092732)
Affinity DataIC50:  5.30E+3nMAssay Description:Inhibitory concentration against Farnesyltransferase for Farnesylation of H-ras protein InNIH 3T3 cells transformed with activated H-rasMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50079812((S)-2-{[(2S,4R)-1-((E)-(R)-4-Amino-5-mercapto-pent...)
Affinity DataIC50:  8.00E+3nMAssay Description:In vitro inhibitory activity against Geranylgeranyl transferase in the geranylgeranylation of H-ras-CAIL proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50366604(CHEMBL1793800 | CHEMBL3349311)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory concentration against Farnesyltransferase for Farnesylation of H-ras protein InNIH 3T3 cells transformed with activated H-rasMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50216998(CHEMBL3349356)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory concentration against Farnesyltransferase for Farnesylation of H-ras protein InNIH 3T3 cells transformed with activated H-rasMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50403713(CHEMBL2092731)
Affinity DataIC50:  1.10E+4nMAssay Description:In vitro inhibitory activity against Geranylgeranyl transferase in the geranylgeranylation of H-ras-CAIL proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50216997(CHEMBL3349355)
Affinity DataIC50:  2.25E+4nMAssay Description:Inhibitory concentration against Farnesyltransferase for Farnesylation of H-ras protein InNIH 3T3 cells transformed with activated H-rasMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50216996(CHEMBL3350225)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibitory concentration against Farnesyltransferase for Farnesylation of H-ras protein InNIH 3T3 cells transformed with activated H-rasMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50403714(CHEMBL2092854 | CHEMBL3350681)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibitory concentration against Farnesyltransferase for Farnesylation of H-ras protein InNIH 3T3 cells transformed with activated H-rasMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50079807(CHEMBL294277 | methyl 2-[1-[4-amino-5-sulfanyl-(E,...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibitory concentration against Farnesyltransferase for Farnesylation of H-ras protein InNIH 3T3 cells transformed with activated H-rasMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50079789(CHEMBL304680 | methyl 2-[1-[4-amino-5-sulfanyl-(E,...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibitory concentration against Farnesyltransferase for Farnesylation of H-ras protein InNIH 3T3 cells transformed with activated H-rasMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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