The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 2.8M data for 1.2M Compounds and 9.2K Targets. Of those, 1,346K data for 622K Compounds and 4.5K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

If BindingDB was of value to your research, please take a moment to donate to this nonprofit project. Your donation will let us provide you with more data and improved service.

Advanced Search

39 articles for thisTarget

The following articles (labelled with PubMed ID or TBD) are for your review

Article Title
Synthesis and serotonergic activity of benzofuran and dihydrogenzofuran analogues of 5-carboxamidotryptamine.EBI
Discovery of 1-[2-(2,4-dimethylphenylsulfanyl)phenyl]piperazine (Lu AA21004): a novel multimodal compound for the treatment of major depressive disorder.EBI
H. Lundbeck
Bivalent Ligands for the Serotonin 5-HT3 Receptor.EBI
Novel, potent, and selective quinoxaline-based 5-HT(3) receptor ligands. 1. Further structure-activity relationships and pharmacological characterization.EBI
European Research Centre For Drug Discovery And Development (Natsyndrugs)
Discovery of N-[(3R,5R)-1-azabicyclo[3.2.1]oct-3-yl]furo[2,3-c]pyridine-5-carboxamide as an agonist of the alpha7 nicotinic acetylcholine receptor: in vitro and in vivo activity.EBI
Activity of alpha7-selective agonists at nicotinic and serotonin 5HT3 receptors expressed in Xenopus oocytes.EBI
University Of Florida
New aza(nor)adamantanes are agonists at the newly identified serotonin 5-HT4 receptor and antagonists at the 5-HT3 receptorEBI
Optimization of 5-pyridazin-3-one phenoxypropylamines as potent, selective histamine H3 receptor antagonists with potent cognition enhancing activity.EBI
New serotonin 5-HT(1A) receptor agonists with neuroprotective effect against ischemic cell damage.EBI
Universidad Complutense De Madrid
Synthesis of heteroaromatic tropeines and heterogeneous binding to glycine receptors.EBI
Hungarian Academy Of Sciences
Synthesis and structure-activity relationships of a new model of arylpiperazines. 8. Computational simulation of ligand-receptor interaction of 5-HT(1A)R agonists with selectivity over alpha1-adrenoceptors.EBI
(S)-4-amino-5-chloro-3-iodo-2-methoxy-N-(1-azabicyclo[2.2.2]oct-3-yl)benzamide (TRIZAC), a high-affinity ligand for the 5-HT-3 receptorEBI
Specific targeting of peripheral serotonin 5-HT(3) receptors. Synthesis, biological investigation, and structure-activity relationships.EBI
European Research Centre For Drug Discovery And Development (Natsyndrugs)
Novel sigma receptor ligands: synthesis and biological profile.EBI
University Of Catania
Structure-Based Design and Optimization of FPPQ, a Dual-Acting 5-HTEBI
Jagiellonian University Medical College
New 1-aryl-3-(4-arylpiperazin-1-yl)propane derivatives, with dual action at 5-HT1A serotonin receptors and serotonin transporter, as a new class of antidepressants.EBI
Universidad De Navarra
Absolute Configuration and Pharmacology of the Poison Frog Alkaloid Phantasmidine.EBI
Indiana State University
Synthesis, biological evaluation and molecular docking of N-phenyl thiosemicarbazones as urease inhibitors.BDB
University Of Karachi
Discovery of isoalloxazine derivatives as a new class of potential anti-Alzheimer agents and their synthesis.BDB
The M. S. University Of Baroda