Compile Data Set for Download or QSAR
Report error Found 40 Enz. Inhib. hit(s) with all data for entry = 6784
TargetCarboxylic ester hydrolase(Horse)
The M. S. University of Baroda

LigandPNGBDBM8961(CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...)
Affinity DataIC50: 8.60nMpH: 8.0 T: 2°CAssay Description:Suitable agents like donepezil hydrochloride and tacrine hydrochloride hydrate were used as standards for this study. Buffer solution (50 mM Tris-HCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2015
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAcetylcholinesterase(Human)
The M. S. University of Baroda

LigandPNGBDBM8960(2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2...)
Affinity DataIC50: 23nMpH: 8.0 T: 2°CAssay Description:Suitable agents like donepezil hydrochloride and tacrine hydrochloride hydrate were used as standards for this study. Buffer solution (50 mM Tris-HCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2015
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAcetylcholinesterase(Human)
The M. S. University of Baroda

LigandPNGBDBM8961(CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...)
Affinity DataIC50: 56nMpH: 8.0 T: 2°CAssay Description:Suitable agents like donepezil hydrochloride and tacrine hydrochloride hydrate were used as standards for this study. Buffer solution (50 mM Tris-HCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2015
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarboxylic ester hydrolase(Horse)
The M. S. University of Baroda

LigandPNGBDBM8960(2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2...)
Affinity DataIC50: 1.87E+3nMpH: 8.0 T: 2°CAssay Description:Suitable agents like donepezil hydrochloride and tacrine hydrochloride hydrate were used as standards for this study. Buffer solution (50 mM Tris-HCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2015
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
The M. S. University of Baroda

LigandPNGBDBM152545(10-(2,3-Dimethoxybenzyl)benzo[g]pteridine-2,4(3H,1...)
Affinity DataIC50: 4.72E+3nMpH: 8.0 T: 2°CAssay Description:Suitable agents like donepezil hydrochloride and tacrine hydrochloride hydrate were used as standards for this study. Buffer solution (50 mM Tris-HCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2015
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
The M. S. University of Baroda

LigandPNGBDBM152549(10-(3,4-Dimethoxyphenethyl)benzo[g]pteridine-2,4(3...)
Affinity DataIC50: 5.22E+3nMpH: 8.0 T: 2°CAssay Description:Suitable agents like donepezil hydrochloride and tacrine hydrochloride hydrate were used as standards for this study. Buffer solution (50 mM Tris-HCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2015
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
The M. S. University of Baroda

LigandPNGBDBM152549(10-(3,4-Dimethoxyphenethyl)benzo[g]pteridine-2,4(3...)
Affinity DataIC50: 5.29E+3nMpH: 8.0 T: 2°CAssay Description:Suitable agents like donepezil hydrochloride and tacrine hydrochloride hydrate were used as standards for this study. Buffer solution (50 mM Tris-HCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2015
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
The M. S. University of Baroda

LigandPNGBDBM152545(10-(2,3-Dimethoxybenzyl)benzo[g]pteridine-2,4(3H,1...)
Affinity DataIC50: 6.98E+3nMpH: 8.0 T: 2°CAssay Description:Suitable agents like donepezil hydrochloride and tacrine hydrochloride hydrate were used as standards for this study. Buffer solution (50 mM Tris-HCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2015
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
The M. S. University of Baroda

LigandPNGBDBM152548(10-(4-Chlorophenethyl)benzo[g]pteridine-2,4(3H,10H...)
Affinity DataIC50: 7.13E+3nMpH: 8.0 T: 2°CAssay Description:Suitable agents like donepezil hydrochloride and tacrine hydrochloride hydrate were used as standards for this study. Buffer solution (50 mM Tris-HCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2015
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
The M. S. University of Baroda

LigandPNGBDBM152539(10-(2-Fluorobenzyl)benzo[g]pteridine-2,4(3H,10H)-d...)
Affinity DataIC50: 7.28E+3nMpH: 8.0 T: 2°CAssay Description:Suitable agents like donepezil hydrochloride and tacrine hydrochloride hydrate were used as standards for this study. Buffer solution (50 mM Tris-HCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2015
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
The M. S. University of Baroda

LigandPNGBDBM152542(10-(4-Chlorobenzyl)benzo[g]pteridine-2,4(3H,10H)-d...)
Affinity DataIC50: 7.39E+3nMpH: 8.0 T: 2°CAssay Description:Suitable agents like donepezil hydrochloride and tacrine hydrochloride hydrate were used as standards for this study. Buffer solution (50 mM Tris-HCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2015
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
The M. S. University of Baroda

LigandPNGBDBM152538(10-(4-Methylbenzyl)benzo[g]pteridine-2,4(3H,10H)-d...)
Affinity DataIC50: 7.89E+3nMpH: 8.0 T: 2°CAssay Description:Suitable agents like donepezil hydrochloride and tacrine hydrochloride hydrate were used as standards for this study. Buffer solution (50 mM Tris-HCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2015
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
The M. S. University of Baroda

LigandPNGBDBM152540(10-(3-Fluorobenzyl)benzo[g]pteridine-2,4(3H,10H)-d...)
Affinity DataIC50: 8.26E+3nMpH: 8.0 T: 2°CAssay Description:Suitable agents like donepezil hydrochloride and tacrine hydrochloride hydrate were used as standards for this study. Buffer solution (50 mM Tris-HCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2015
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
The M. S. University of Baroda

LigandPNGBDBM152543(10-(2-Methoxybenzyl)benzo[g]pteridine-2,4(3H,10H)-...)
Affinity DataIC50: 8.39E+3nMpH: 8.0 T: 2°CAssay Description:Suitable agents like donepezil hydrochloride and tacrine hydrochloride hydrate were used as standards for this study. Buffer solution (50 mM Tris-HCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2015
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
The M. S. University of Baroda

LigandPNGBDBM152546(10-(3,4-Dimethoxybenzyl)benzo[g]pteridine-2,4(3H,1...)
Affinity DataIC50: 8.55E+3nMpH: 8.0 T: 2°CAssay Description:Suitable agents like donepezil hydrochloride and tacrine hydrochloride hydrate were used as standards for this study. Buffer solution (50 mM Tris-HCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2015
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
The M. S. University of Baroda

LigandPNGBDBM152533(10-Propylbenzo[g]pteridine-2,4(3H,10H)-dione (7a))
Affinity DataIC50: 9.32E+3nMpH: 8.0 T: 2°CAssay Description:Suitable agents like donepezil hydrochloride and tacrine hydrochloride hydrate were used as standards for this study. Buffer solution (50 mM Tris-HCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2015
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
The M. S. University of Baroda

LigandPNGBDBM152544(10-(4-Methoxybenzyl)benzo[g]pteridine-2,4(3H,10H)-...)
Affinity DataIC50: 9.34E+3nMpH: 8.0 T: 2°CAssay Description:Suitable agents like donepezil hydrochloride and tacrine hydrochloride hydrate were used as standards for this study. Buffer solution (50 mM Tris-HCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2015
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
The M. S. University of Baroda

LigandPNGBDBM152541(10-(3-Chlorobenzyl)benzo[g]pteridine-2,4(3H,10H)-d...)
Affinity DataIC50: 1.05E+4nMpH: 8.0 T: 2°CAssay Description:Suitable agents like donepezil hydrochloride and tacrine hydrochloride hydrate were used as standards for this study. Buffer solution (50 mM Tris-HCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2015
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
The M. S. University of Baroda

LigandPNGBDBM152535(10-Allylbenzo[g]pteridine-2,4(3H,10H)-dione (7c))
Affinity DataIC50: 1.12E+4nMpH: 8.0 T: 2°CAssay Description:Suitable agents like donepezil hydrochloride and tacrine hydrochloride hydrate were used as standards for this study. Buffer solution (50 mM Tris-HCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2015
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
The M. S. University of Baroda

LigandPNGBDBM152540(10-(3-Fluorobenzyl)benzo[g]pteridine-2,4(3H,10H)-d...)
Affinity DataIC50: 1.15E+4nMpH: 8.0 T: 2°CAssay Description:Suitable agents like donepezil hydrochloride and tacrine hydrochloride hydrate were used as standards for this study. Buffer solution (50 mM Tris-HCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2015
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
The M. S. University of Baroda

LigandPNGBDBM152536(10-Benzylbenzo[g]pteridine-2,4(3H,10H)-dione (7d))
Affinity DataIC50: 1.15E+4nMpH: 8.0 T: 2°CAssay Description:Suitable agents like donepezil hydrochloride and tacrine hydrochloride hydrate were used as standards for this study. Buffer solution (50 mM Tris-HCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2015
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
The M. S. University of Baroda

LigandPNGBDBM152537(10-(3-Methylbenzyl)benzo[g]pteridine-2,4(3H,10H)-d...)
Affinity DataIC50: 1.16E+4nMpH: 8.0 T: 2°CAssay Description:Suitable agents like donepezil hydrochloride and tacrine hydrochloride hydrate were used as standards for this study. Buffer solution (50 mM Tris-HCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2015
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
The M. S. University of Baroda

LigandPNGBDBM152534(10-Butylbenzo[g]pteridine-2,4(3H,10H)-dione (7b))
Affinity DataIC50: 1.22E+4nMpH: 8.0 T: 2°CAssay Description:Suitable agents like donepezil hydrochloride and tacrine hydrochloride hydrate were used as standards for this study. Buffer solution (50 mM Tris-HCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2015
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
The M. S. University of Baroda

LigandPNGBDBM152543(10-(2-Methoxybenzyl)benzo[g]pteridine-2,4(3H,10H)-...)
Affinity DataIC50: 1.88E+4nMpH: 8.0 T: 2°CAssay Description:Suitable agents like donepezil hydrochloride and tacrine hydrochloride hydrate were used as standards for this study. Buffer solution (50 mM Tris-HCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2015
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
The M. S. University of Baroda

LigandPNGBDBM152539(10-(2-Fluorobenzyl)benzo[g]pteridine-2,4(3H,10H)-d...)
Affinity DataIC50: 2.16E+4nMpH: 8.0 T: 2°CAssay Description:Suitable agents like donepezil hydrochloride and tacrine hydrochloride hydrate were used as standards for this study. Buffer solution (50 mM Tris-HCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2015
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
The M. S. University of Baroda

LigandPNGBDBM152547(10-Phenethylbenzo[g]pteridine-2,4(3H,10H)-dione (7...)
Affinity DataIC50: 2.34E+4nMpH: 8.0 T: 2°CAssay Description:Suitable agents like donepezil hydrochloride and tacrine hydrochloride hydrate were used as standards for this study. Buffer solution (50 mM Tris-HCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2015
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
The M. S. University of Baroda

LigandPNGBDBM152535(10-Allylbenzo[g]pteridine-2,4(3H,10H)-dione (7c))
Affinity DataIC50: 2.72E+4nMpH: 8.0 T: 2°CAssay Description:Suitable agents like donepezil hydrochloride and tacrine hydrochloride hydrate were used as standards for this study. Buffer solution (50 mM Tris-HCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2015
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
The M. S. University of Baroda

LigandPNGBDBM152538(10-(4-Methylbenzyl)benzo[g]pteridine-2,4(3H,10H)-d...)
Affinity DataIC50: 2.94E+4nMpH: 8.0 T: 2°CAssay Description:Suitable agents like donepezil hydrochloride and tacrine hydrochloride hydrate were used as standards for this study. Buffer solution (50 mM Tris-HCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2015
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
The M. S. University of Baroda

LigandPNGBDBM152548(10-(4-Chlorophenethyl)benzo[g]pteridine-2,4(3H,10H...)
Affinity DataIC50: 2.95E+4nMpH: 8.0 T: 2°CAssay Description:Suitable agents like donepezil hydrochloride and tacrine hydrochloride hydrate were used as standards for this study. Buffer solution (50 mM Tris-HCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2015
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
The M. S. University of Baroda

LigandPNGBDBM152542(10-(4-Chlorobenzyl)benzo[g]pteridine-2,4(3H,10H)-d...)
Affinity DataIC50: 3.00E+4nMpH: 8.0 T: 2°CAssay Description:Suitable agents like donepezil hydrochloride and tacrine hydrochloride hydrate were used as standards for this study. Buffer solution (50 mM Tris-HCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2015
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
The M. S. University of Baroda

LigandPNGBDBM152536(10-Benzylbenzo[g]pteridine-2,4(3H,10H)-dione (7d))
Affinity DataIC50: 3.17E+4nMpH: 8.0 T: 2°CAssay Description:Suitable agents like donepezil hydrochloride and tacrine hydrochloride hydrate were used as standards for this study. Buffer solution (50 mM Tris-HCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2015
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
The M. S. University of Baroda

LigandPNGBDBM152546(10-(3,4-Dimethoxybenzyl)benzo[g]pteridine-2,4(3H,1...)
Affinity DataIC50: 3.26E+4nMpH: 8.0 T: 2°CAssay Description:Suitable agents like donepezil hydrochloride and tacrine hydrochloride hydrate were used as standards for this study. Buffer solution (50 mM Tris-HCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2015
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
The M. S. University of Baroda

LigandPNGBDBM152533(10-Propylbenzo[g]pteridine-2,4(3H,10H)-dione (7a))
Affinity DataIC50: 4.04E+4nMpH: 8.0 T: 2°CAssay Description:Suitable agents like donepezil hydrochloride and tacrine hydrochloride hydrate were used as standards for this study. Buffer solution (50 mM Tris-HCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2015
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
The M. S. University of Baroda

LigandPNGBDBM152537(10-(3-Methylbenzyl)benzo[g]pteridine-2,4(3H,10H)-d...)
Affinity DataIC50: 4.29E+4nMpH: 8.0 T: 2°CAssay Description:Suitable agents like donepezil hydrochloride and tacrine hydrochloride hydrate were used as standards for this study. Buffer solution (50 mM Tris-HCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2015
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
The M. S. University of Baroda

LigandPNGBDBM152534(10-Butylbenzo[g]pteridine-2,4(3H,10H)-dione (7b))
Affinity DataIC50: 4.37E+4nMpH: 8.0 T: 2°CAssay Description:Suitable agents like donepezil hydrochloride and tacrine hydrochloride hydrate were used as standards for this study. Buffer solution (50 mM Tris-HCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2015
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
The M. S. University of Baroda

LigandPNGBDBM152544(10-(4-Methoxybenzyl)benzo[g]pteridine-2,4(3H,10H)-...)
Affinity DataIC50: 4.72E+4nMpH: 8.0 T: 2°CAssay Description:Suitable agents like donepezil hydrochloride and tacrine hydrochloride hydrate were used as standards for this study. Buffer solution (50 mM Tris-HCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2015
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
The M. S. University of Baroda

LigandPNGBDBM152541(10-(3-Chlorobenzyl)benzo[g]pteridine-2,4(3H,10H)-d...)
Affinity DataIC50: 4.73E+4nMpH: 8.0 T: 2°CAssay Description:Suitable agents like donepezil hydrochloride and tacrine hydrochloride hydrate were used as standards for this study. Buffer solution (50 mM Tris-HCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2015
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
The M. S. University of Baroda

LigandPNGBDBM152547(10-Phenethylbenzo[g]pteridine-2,4(3H,10H)-dione (7...)
Affinity DataIC50: 5.28E+4nMpH: 8.0 T: 2°CAssay Description:Suitable agents like donepezil hydrochloride and tacrine hydrochloride hydrate were used as standards for this study. Buffer solution (50 mM Tris-HCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2015
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
The M. S. University of Baroda

LigandPNGBDBM152532(Benzo[g]pteridine-2,4(3H,10H)-dione (7))
Affinity DataIC50: 5.56E+4nMpH: 8.0 T: 2°CAssay Description:Suitable agents like donepezil hydrochloride and tacrine hydrochloride hydrate were used as standards for this study. Buffer solution (50 mM Tris-HCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2015
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
The M. S. University of Baroda

LigandPNGBDBM152532(Benzo[g]pteridine-2,4(3H,10H)-dione (7))
Affinity DataIC50: 6.45E+4nMpH: 8.0 T: 2°CAssay Description:Suitable agents like donepezil hydrochloride and tacrine hydrochloride hydrate were used as standards for this study. Buffer solution (50 mM Tris-HCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2015
Entry Details Article
PubMed