BDBM50017696 (2-dimethylamino-2-methyl)ethyl-N-dibenzoparathiazine::10-(2-Dimethylaminopropyl)phenothiazine::10-[2-(dimethylamino)propyl]phenothiazine::CHEMBL643::N,N,alpha-trimethyl-10H-phenothiazine-10-ethanamine::N,N-dimethyl-1-(10H-phenothiazin-10-yl)propan-2-amine::PROMETHAZINE::med.21724, Compound 16::proazamine
SMILES CC(CN1c2ccccc2Sc2ccccc12)N(C)C
InChI Key InChIKey=PWWVAXIEGOYWEE-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 33 hits for monomerid = 50017696
TargetHistamine H4 receptor(Homo sapiens (Human))
The Centre For Addiction And Mental Health
Curated by PDSP Ki Database
The Centre For Addiction And Mental Health
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
College Of France
Curated by PDSP Ki Database
College Of France
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
College Of France
Curated by PDSP Ki Database
College Of France
Curated by PDSP Ki Database
Affinity DataKi: 2.16E+5nMAssay Description:Inhibitory activity against recombinant Trypanosoma cruzi (T. cruzi) Trypanothione reductase (linear competitive type)More data for this Ligand-Target Pair
Affinity DataIC50: 5.86E+3nMAssay Description:This is a review article.More data for this Ligand-Target Pair
Affinity DataIC50: 2.14E+4nMAssay Description:This is a review article.More data for this Ligand-Target Pair
Affinity DataEC50: 1.18E+4nMAssay Description:This is a review article.More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
University Of Bonn
University Of Bonn
Affinity DataEC50: 7.54E+3nMAssay Description:This is a review article.More data for this Ligand-Target Pair
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP2 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.35E+5nMAssay Description:Inhibition of human BSEP expressed in fall armyworm sf9 cell plasma membrane vesicles assessed as reduction in vesicle-associated [3H]-taurocholate t...More data for this Ligand-Target Pair
TargetPleiotropic ABC efflux transporter of multiple drugs(Saccharomyces cerevisiae S288c)
Wroclaw Medical University
Curated by ChEMBL
Wroclaw Medical University
Curated by ChEMBL
Affinity DataIC50: 1.77E+4nMAssay Description:Inhibition of Pdr5p-mediated rhodamine 6G transport in Saccharomyces cerevisiae MKPDR5h plasma membrane by spectrofluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.51E+4nMAssay Description:Inhibition of 4-(4-(dimethylamino)styryl)-N-methylpyridinium uptake at human OCT1 expressed in HEK293 cells by confocal microscopyMore data for this Ligand-Target Pair
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Binding affinity to dopamine D2 receptor (unknown origin) by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.40nMAssay Description:Binding affinity to histamine H1 receptor (unknown origin) by radioligand binding assayMore data for this Ligand-Target Pair
TargetMajor prion protein(Homo sapiens (Human))
Institut F£R Molekularbiologie Und Biophysik
Curated by ChEMBL
Institut F£R Molekularbiologie Und Biophysik
Curated by ChEMBL
Affinity DataEC50: 8.00E+3nMAssay Description:Half maximal inhibition of Prion protein PrPsc formation was assayed in ScN2a cellsMore data for this Ligand-Target Pair
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of endogenous human CaV2.2 in human SH-SY5Y cells in presence of nifedipine by Calcium 4 dye based calcium influx fluorescence-imaging ass...More data for this Ligand-Target Pair
Affinity DataKd: 5.00E+4nMAssay Description:Binding affinity to bovine brain CaM by FTPFACE analysisMore data for this Ligand-Target Pair
TargetChloroquine resistance transporter(Plasmodium falciparum)
Australian National University
Curated by ChEMBL
Australian National University
Curated by ChEMBL
Affinity DataIC50: 8.50E+4nMAssay Description:Inhibition of chloroquine-resistant Plasmodium falciparum Dd2 CRT expressed in Xenopus laevis oocytes plasma membrane assessed as reduction of [3H]-c...More data for this Ligand-Target Pair
Affinity DataIC50: 6.00E+4nMAssay Description:Binding affinity to CaM (unknown origin) by equilibrium dialysis methodMore data for this Ligand-Target Pair