BDBM14361 (R,S)-Rolipram::4-(3-cyclopentyloxy-4-methoxy-phenyl)pyrrolidin-2-one::4-[3-(cyclopentyloxy)-4-methoxyphenyl]pyrrolidin-2-one::Adeo::CHEMBL63::Rolipram
SMILES COc1ccc(cc1OC1CCCC1)C1CNC(=O)C1
InChI Key InChIKey=HJORMJIFDVBMOB-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 14361
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Zambon Group
Curated by ChEMBL
Zambon Group
Curated by ChEMBL
Affinity DataKi: 1.60nMAssay Description:Inhibition of human VCAM and Ramos cell VLA-4 interactionMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Zambon Group
Curated by ChEMBL
Zambon Group
Curated by ChEMBL
Affinity DataKi: 1.60nMAssay Description:Inhibition of rolipram binding to PDE4 from human neutrophilsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Zambon Group
Curated by ChEMBL
Zambon Group
Curated by ChEMBL
Affinity DataIC50: 1.68E+3nMAssay Description:Inhibition of human Phosphodiesterase 4More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Zambon Group
Curated by ChEMBL
Zambon Group
Curated by ChEMBL
Affinity DataIC50: 1.68E+3nMAssay Description:Inhibition of Phosphodiesterase 4 from human neutrophilsMore data for this Ligand-Target Pair