BDBM14361 (R,S)-Rolipram::4-(3-cyclopentyloxy-4-methoxy-phenyl)pyrrolidin-2-one::4-[3-(cyclopentyloxy)-4-methoxyphenyl]pyrrolidin-2-one::Adeo::CHEMBL63::Rolipram
SMILES COc1ccc(cc1OC1CCCC1)C1CNC(=O)C1
InChI Key InChIKey=HJORMJIFDVBMOB-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 14361
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University
Curated by ChEMBL
South China Agricultural University
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human U-937 cells derived PDE4B using [3H] cAMP as substrate measured after 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
South China Agricultural University
Curated by ChEMBL
South China Agricultural University
Curated by ChEMBL
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of human U-937 cells derived PDE4D using [3H] cAMP as substrate measured after 30 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
South China Agricultural University
Curated by ChEMBL
South China Agricultural University
Curated by ChEMBL
Affinity DataIC50: 1.89E+4nMAssay Description:Inhibition of PDE4B in human PBMC assessed as reduction in LPS-induced TNFalpha release preincubated for 30 mins followed by LPS stimulation and meas...More data for this Ligand-Target Pair