BDBM50036127 CHEMBL11391::{2-Oxo-6-phenyl-1-[(3,3,3-trifluoro-1-isopropyl-2-oxo-propylcarbamoyl)-methyl]-1,2-dihydro-pyridin-3-yl}-carbamic acid benzyl ester
SMILES CC(C)C(NC(=O)Cn1c(ccc(NC(=O)OCc2ccccc2)c1=O)-c1ccccc1)C(=O)C(F)(F)F
InChI Key InChIKey=MQIPGYPHWSTWGE-UHFFFAOYSA-N
Data 12 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 50036127
Affinity DataKi: 4.5nMAssay Description:Inhibition of Human Neutrophil Elastase-catalyzed hydrolysis of the synthetic substrate MeO-Suc-Ala-Ala-Pro-Val-p- nitroanilide.More data for this Ligand-Target Pair
Affinity DataKi: 4.5nMAssay Description:Inhibition of Human Leukocyte Elastase (HLE)More data for this Ligand-Target Pair
Affinity DataKi: 4.5nMAssay Description:Tested for inhibitory activity against human leukocyte elastase(HLE) enzymeMore data for this Ligand-Target Pair
Affinity DataKi: 4.5nMAssay Description:Inhibition of Human Neutrophil Elastase-catalyzed hydrolysis of the synthetic substrate MeO-Suc-Ala-Ala-Pro-Val-p- nitroanilide.More data for this Ligand-Target Pair
Affinity DataKi: 4.5nMAssay Description:Binding affinity against human leukocyte elastase (HLE) enzymeMore data for this Ligand-Target Pair
Affinity DataKi: 4.5nMAssay Description:Inhibition of human HLEMore data for this Ligand-Target Pair
Affinity DataKi: 5.60nMAssay Description:In vitro inhibition of human leukocyte elastase mediated hydrolysis of the synthetic substrate MeO-Suc-Ala-Ala-Pro-Val-pNAMore data for this Ligand-Target Pair
Affinity DataKi: 55nMAssay Description:Tested for inhibitory activity against bovine pancreatic chymotrypsinogenMore data for this Ligand-Target Pair
Affinity DataKi: 55nMAssay Description:The compound was evaluated for the binding affinity against bovine pancreatic chymotrypsinogenMore data for this Ligand-Target Pair
Affinity DataKi: 4.60E+3nMAssay Description:Inhibitory activity against porcine pancreatic elastaseMore data for this Ligand-Target Pair
Affinity DataKi: 4.80E+3nMAssay Description:Inhibitory activity against bovine pancreatic trypsinMore data for this Ligand-Target Pair
Affinity DataKi: 7.00E+3nMAssay Description:Inhibitory activity against papainMore data for this Ligand-Target Pair