BDBM50193796 3,3-dimethyl-1-[5-(1H-tetrazol-5-yl)-adamantan-2-yl]-4-(5-trifluoromethyl-pyridin-2-yloxymethyl)-pyrrolidin-2-one::CHEMBL218570

SMILES CC1(C)C(COc2ccc(cn2)C(F)(F)F)CN([C@H]2C3CC4CC2C[C@](C4)(C3)c2nnn[nH]2)C1=O

InChI Key

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50193796   

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193796(3,3-dimethyl-1-[5-(1H-tetrazol-5-yl)-adamantan-2-y...)
Affinity DataIC50: 230nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193796(3,3-dimethyl-1-[5-(1H-tetrazol-5-yl)-adamantan-2-y...)
Affinity DataIC50: 310nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193796(3,3-dimethyl-1-[5-(1H-tetrazol-5-yl)-adamantan-2-y...)
Affinity DataIC50: 430nMAssay Description:Inhibition of mouse 11beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193796(3,3-dimethyl-1-[5-(1H-tetrazol-5-yl)-adamantan-2-y...)
Affinity DataIC50: 630nMAssay Description:Inhibition of human 11beta-HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Mouse)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50193796(3,3-dimethyl-1-[5-(1H-tetrazol-5-yl)-adamantan-2-y...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of mouse 11beta-HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed