BDBM50252780 CHEMBL494470::N-Cyclopropyl-3-(1-(4-morpholinyl)-6-phthalazinyl)benzamide

SMILES O=C(NC1CC1)c1cccc(c1)-c1ccc2c(nncc2c1)N1CCOCC1

InChI Key InChIKey=KNLFQURAVAITLS-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50252780   

TargetMitogen-activated protein kinase 14(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50252780(N-Cyclopropyl-3-(1-(4-morpholinyl)-6-phthalazinyl)...)
Affinity DataIC50: 182nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50252780(N-Cyclopropyl-3-(1-(4-morpholinyl)-6-phthalazinyl)...)
Affinity DataIC50: 8.33E+3nMAssay Description:Inhibition of cKitMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50252780(N-Cyclopropyl-3-(1-(4-morpholinyl)-6-phthalazinyl)...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50252780(N-Cyclopropyl-3-(1-(4-morpholinyl)-6-phthalazinyl)...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50252780(N-Cyclopropyl-3-(1-(4-morpholinyl)-6-phthalazinyl)...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50252780(N-Cyclopropyl-3-(1-(4-morpholinyl)-6-phthalazinyl)...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50252780(N-Cyclopropyl-3-(1-(4-morpholinyl)-6-phthalazinyl)...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed