BDBM50252780 CHEMBL494470::N-Cyclopropyl-3-(1-(4-morpholinyl)-6-phthalazinyl)benzamide

SMILES O=C(NC1CC1)c1cccc(c1)-c1ccc2c(nncc2c1)N1CCOCC1

InChI Key InChIKey=KNLFQURAVAITLS-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50252780   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50252780(CHEMBL494470 | N-Cyclopropyl-3-(1-(4-morpholinyl)-...)
Affinity DataIC50:  182nMAssay Description:Inhibition of p38alpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50252780(CHEMBL494470 | N-Cyclopropyl-3-(1-(4-morpholinyl)-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of KDR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50252780(CHEMBL494470 | N-Cyclopropyl-3-(1-(4-morpholinyl)-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Lck (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50252780(CHEMBL494470 | N-Cyclopropyl-3-(1-(4-morpholinyl)-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of JNK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50252780(CHEMBL494470 | N-Cyclopropyl-3-(1-(4-morpholinyl)-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of JNK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50252780(CHEMBL494470 | N-Cyclopropyl-3-(1-(4-morpholinyl)-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of JNK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50252780(CHEMBL494470 | N-Cyclopropyl-3-(1-(4-morpholinyl)-...)
Affinity DataIC50: >8.33E+3nMAssay Description:Inhibition of cKit (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed