BDBM50289001 2-(2-Iodo-phenyl)-6,7-dimethoxy-benzo[d][1,3]oxazin-4-one::CHEMBL349763::US9695194, 18
SMILES COc1cc2nc(oc(=O)c2cc1OC)-c1ccccc1I
InChI Key InChIKey=HKRJBRGRGFMQJI-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50289001
Affinity DataKi: 100nM ΔG°: -9.93kcal/molepH: 7.2 T: 37°CAssay Description:Materials: Recombinant human KLK7, Substrate S-2586 (Chromogenics, cat. no. 820894) KLK7 activity was determined at 37° C. in 10 mM Na phosphate ...More data for this Ligand-Target Pair
Affinity DataKi: 1.90E+3nM ΔG°: -8.11kcal/molepH: 7.2 T: 37°CAssay Description:Materials: Cathepsin G, 100 mU (VWR, Calbiochem, cat. no. 219373), Substrate Cathepsin G substrate (VWR, Calbiochem, cat. no. 219407). Cathepsin acti...More data for this Ligand-Target Pair
Affinity DataKi: 2.10E+3nM ΔG°: -8.05kcal/molepH: 8.0 T: 37°CAssay Description:Materials: Recombinant human KLK14, Substrate S-2302 (Chromogenics, cat. no. 820340). KLK14 activity was determined at 37° C. in 0.1 mM Tris, pH ...More data for this Ligand-Target Pair
Affinity DataKi: 4.50E+3nM ΔG°: -7.58kcal/molepH: 8.0 T: 37°CAssay Description:Materials: Recombinant human KLK5, Substrate S-2288 (Chromogenics, cat. no. 820852) KLK5 activity was determined at 37° C. in 0.1 M Tris, pH 8.0,...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nM ΔG°: >-7.09kcal/molepH: 7.2 T: 37°CAssay Description:Materials: Chymotrypsin, bovine, 25 ug (Roche, sequence grade), Substrate S-2586 (Chromogenics, cat. no. 82 08 94). Chymotrypsin activity was determi...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nM ΔG°: >-7.09kcal/molepH: 8.3 T: 37°CAssay Description:Materials: Thrombin (Chromogenics, cat. no. 820712), Substrate S-2288 (Chromogenics, cat. no. 82 08 52). Thrombin activity was determined at 37° ...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nM ΔG°: >-7.09kcal/molepH: 7.2 T: 37°CAssay Description:Materials: Trypsin, 100 ug (Roche, sequence grade, Mw 23500), Substrate S-2288 (Chromogenics, cat. no. 820852). Trypsin activity was determined at 3...More data for this Ligand-Target Pair
Affinity DataIC50: >6.25E+4nMAssay Description:Inhibitory activity against C1r serine proteaseMore data for this Ligand-Target Pair
Affinity DataIC50: >6.25E+4nMAssay Description:Inhibition of C1r serine proteaseMore data for this Ligand-Target Pair