BDBM50312803 (3aS,8aR)-3a,8-dimethyl-1-phenethyl-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indol-5-yl 4-isopropylphenylcarbamate::3alpha,8-dimethyl-1-phenethyl-1,2,3,3alpha,8,8alpha-hexahydropyrrolo[2,3-b]indol-5-yl 4-isopropylphenylcarbamate::CHEMBL1080386

SMILES CC(C)c1ccc(NC(=O)Oc2ccc3N(C)[C@H]4N(CCc5ccccc5)CC[C@@]4(C)c3c2)cc1

InChI Key InChIKey=WKDFOVDLOVYRAJ-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50312803   

TargetAcetylcholinesterase(Human)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50312803(3alpha,8-dimethyl-1-phenethyl-1,2,3,3alpha,8,8alph...)
Affinity DataIC50: 6nMAssay Description:Inhibition of human plasma BChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50312803(3alpha,8-dimethyl-1-phenethyl-1,2,3,3alpha,8,8alph...)
Affinity DataIC50: 6nMAssay Description:Inhibition of human erythrocytes BChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetCholinesterase(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50312803(3alpha,8-dimethyl-1-phenethyl-1,2,3,3alpha,8,8alph...)
Affinity DataIC50: 6nMAssay Description:Inhibition of BChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetCholinesterase(Mouse)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50312803(3alpha,8-dimethyl-1-phenethyl-1,2,3,3alpha,8,8alph...)
Affinity DataIC50: 540nMAssay Description:Inhibition of mouse serum BChE after 1 hr by modified Ellman's colorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetCholinesterase(Mouse)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50312803(3alpha,8-dimethyl-1-phenethyl-1,2,3,3alpha,8,8alph...)
Affinity DataIC50: 540nMAssay Description:Inhibition of mouse serum BChE after 1 hr by modified Ellman's colorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50312803(3alpha,8-dimethyl-1-phenethyl-1,2,3,3alpha,8,8alph...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human plasma AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50312803(3alpha,8-dimethyl-1-phenethyl-1,2,3,3alpha,8,8alph...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50312803(3alpha,8-dimethyl-1-phenethyl-1,2,3,3alpha,8,8alph...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human erythrocytes AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Mouse)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50312803(3alpha,8-dimethyl-1-phenethyl-1,2,3,3alpha,8,8alph...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of mouse brain AChE after 1 hr by modified Ellman's colorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Mouse)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50312803(3alpha,8-dimethyl-1-phenethyl-1,2,3,3alpha,8,8alph...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of mouse brain AChE after 1 hr by modified Ellman's colorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed