BDBM764986 4-((1-(4-(6-(trifluoromethyl) pyridin-2-yl)piperazine-1-car bonyl)cyclopentyl)amino)benz onitrile::US12391660, Compound 11

SMILES N#Cc4ccc(NC3(C(=O)N2CCN(c1cccc(C(F)(F)F)n1)CC2)CCCC3)cc4

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 764986   

TargetTransient receptor potential cation channel subfamily A member 1(Human)
Hangzhou Westan Pharmaceutical Technology

US Patent
LigandPNGBDBM764986(4-((1-(4-(6-(trifluoromethyl) pyridin-2-yl)piperaz...)
Affinity DataIC50: 19nMAssay Description:Table 3.1: The cell analysis plate was placed in an FLIPR instrument (Molecular Probes), and the compound in the compound plate was added to the corr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetTransient receptor potential cation channel subfamily A member 1(Human)
Hangzhou Westan Pharmaceutical Technology

US Patent
LigandPNGBDBM764986(4-((1-(4-(6-(trifluoromethyl) pyridin-2-yl)piperaz...)
Affinity DataIC50: 35nMAssay Description:Table 3.2: The cells were transferred to the perfusion tank and perfused with extracellular fluid. The intracellular fluid was: 130 mM K-aspartate; 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent