BDBM792926 US12552795, Compound 3::US20260138986, Compound 3
SMILES C[C@@H](O)Cn1cc(-c2cc3c(N4CCN(c5ncc([C@@](C)(N)c6ccc(F)cc6)cn5)CC4)ncnn3c2)cn1
InChI Key InChIKey=OPOILSUUPUWPEK-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 14 hits for monomerid = 792926
Affinity DataKd: <0.300nMAssay Description:The primary screen was performed by transient transactivation assays. These cell-based assays were carried out using Cos-7 cells transfected with a c...More data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:All test articles were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of all test compounds was c...More data for this Ligand-Target Pair
Affinity DataKd: <0.300nMAssay Description:The primary screen was performed by transient transactivation assays. These cell-based assays were carried out using Cos-7 cells transfected with a c...More data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:All test articles were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of all test compounds was c...More data for this Ligand-Target Pair
Affinity DataKd: <10nMAssay Description:Kd Determinations. For most assays, including wt KIT kinase, kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 st...More data for this Ligand-Target Pair
Affinity DataKd: <10nMAssay Description:The primary screen was performed by transient transactivation assays. These cell-based assays were carried out using Cos-7 cells transfected with a c...More data for this Ligand-Target Pair
Affinity DataIC50: 3.99E+3nMAssay Description:In vitro studies in human liver microsomes were run according the standard method. In summary, seven different concentration of the test article or a...More data for this Ligand-Target Pair
Affinity DataIC50: 3.99E+3nMAssay Description:The primary screen was performed by transient transactivation assays. These cell-based assays were carried out using Cos-7 cells transfected with a c...More data for this Ligand-Target Pair
Affinity DataIC50: 6.55E+3nMAssay Description:In vitro studies in human liver microsomes were run according the standard method. In summary, seven different concentration of the test article or a...More data for this Ligand-Target Pair
Affinity DataIC50: 6.55E+3nMAssay Description:The primary screen was performed by transient transactivation assays. These cell-based assays were carried out using Cos-7 cells transfected with a c...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro studies in human liver microsomes were run according the standard method. In summary, seven different concentration of the test article or a...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:The primary screen was performed by transient transactivation assays. These cell-based assays were carried out using Cos-7 cells transfected with a c...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro studies in human liver microsomes were run according the standard method. In summary, seven different concentration of the test article or a...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:The primary screen was performed by transient transactivation assays. These cell-based assays were carried out using Cos-7 cells transfected with a c...More data for this Ligand-Target Pair